Spots Global Cancer Trial Database for Acute Effect of modeRate-intensity aerOBIc Exercise on Colon Cancer Cell Growth

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Trial Identification

Brief Title: Acute Effect of modeRate-intensity aerOBIc Exercise on Colon Cancer Cell Growth

Official Title: Effect of a Single Bout of Moderate-intensity Aerobic Exercise on Colon Cancer Cell Growth in Vitro

Study ID: NCT04057274

Conditions

Colon Adenocarcinoma

Colon Cancer

Interventions

Exercise assessment

Study Description

Brief Summary: This study involves drawing blood samples from men before and after they perform 30-minutes of moderate-intensity aerobic exercise. The investigators will evaluate whether adding the exercise serum to colon cancer cells in a dish can reduce the growth of the cells compared to the resting serum. Note: serum is the liquid part of the blood that carries hormones and metabolites around the body.

Detailed Description: Regular exercise is associated with a reduced risk of developing colon cancer. However, the mechanisms underpinning the anti-cancer effect of exercise are not yet fully understood. A recent theory suggests that each time you exercise, the short-lasting spikes in circulating hormones can suppress the growth of cancer cells. Hence, every exercise bout could have a direct anti-cancer effect. This study will recruit men with an increased of colon cancer and explore whether incubating colon cancer cells with serum collected after a bout of moderate-intensity aerobic exercise influences cell viability in vitro.