Spots Global Cancer Trial Database for ASPIRIN Trial Belgium
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Trial Identification
Brief Title: ASPIRIN Trial Belgium
Official Title: A Phase III Double-blind Placebo-controlled Randomised Trial of Aspirin on Recurrence and Survival in Colon Cancer Patients
Study ID: NCT03464305
Conditions
Study Description
Brief Summary: The purpose of this study is to determine whether acetylsalicylic acid is effective on the recurrence and survival of colon cancer patients.
Detailed Description: The purpose of this study is to determine the effect of 80mg acetylsalicylic acid (given orally once daily for 5 years) on 5 year overall survival (OS) for stage II and III colon cancer patients of 45 years of age and older. Preclinical, epidemiologic and clinical evidence suggest that acetylsalicylic acid use may reduce overall cancer risk and mortality in colon cancer patients. It is a phase III double blind placebo controlled, randomized trial of adjuvant low-dose acetylsalicylic acid in colon cancer patients. Patients will be stratified at randomization by centre, age (\<70 and ≥70 years) chemotherapy use (any versus none) and disease stage.
Eligibility
Minimum Age: 45 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
AZ Rivierenland campus Bornem (Sint Jozefkliniek), Bornem, Antwerpen, Belgium
AZ Klina, Brasschaat, Antwerpen, Belgium
AZ Monica, Deurne, Antwerpen, Belgium
UZ Antwerpen, Edegem, Antwerpen, Belgium
AZ Rivierenland campus Rumst (Heilige Familie), Rumst, Antwerpen, Belgium
VITAZ (AZ Nikolaas), Sint-Niklaas, Oost-Vlaanderen, Belgium
Ziekenhuis Netwerk Antwerpen (ZNA), Antwerpen, , Belgium
Gasthuiszusters Ziekenhuizen (GZA), Antwerpen, , Belgium
Clinique Saint-Luc, Bouge, , Belgium
AZ Sint-Lucas, Brugge, , Belgium
CHIREC, Brussels, , Belgium
Grand Hôpital de Charleroi, Charleroi, , Belgium
AZ Sint-Blasius, Dendermonde, , Belgium
AZ Alma, Eeklo, , Belgium
AZ Sint-Dimpna, Geel, , Belgium
AZ Maria Middelares, Gent, , Belgium
Jessa Ziekenhuis, Hasselt, , Belgium
AZ Groeninge, Kortrijk, , Belgium
RZ Heilig Hart, Leuven, , Belgium
CH de l'Ardenne, Libramont, , Belgium
CHR de la Citadelle, Liège, , Belgium
CHU Ambroise Paré, Mons, , Belgium
CH de Mouscron, Mouscron, , Belgium
CHU UCL Namur Site de Sainte-Elisabeth, Namur, , Belgium
Clinique Saint-Pierre, Ottignies-Louvain-la-Neuve, , Belgium
AZ Glorieux, Ronse, , Belgium
AZ Sint-Trudo, Sint-Truiden, , Belgium
CHR Verviers, Verviers, , Belgium
OLV van Lourdes Ziekenhuis, Waregem, , Belgium
Contact Details
Name: Marc Peeters, Prof dr
Affiliation: University Hospital, Antwerp
Role: PRINCIPAL_INVESTIGATOR
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