Spots Global Cancer Trial Database for Cryptosporidium Infection and Human Colorectal Cancer
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Trial Identification
Brief Title: Cryptosporidium Infection and Human Colorectal Cancer
Official Title: Role of the Protozoa Cryptosporidium in the Development of Colorectal Cancer in Humans
Study ID: NCT04332705
Interventions
Study Description
Brief Summary: It has been reported that Cryptosporidium parvum, a species of a protozoan frequently isolated from humans and animals, is able to induce digestive adenocarcinoma in a rodent model. Consistently, some epidemiological studies have reported an association with cryptosporidiosis in patients with colorectal adenocarcinoma. However, the correlation between cryptosporidiosis and human digestive cancer remains unclear at this time, and it is not known whether this intracellular parasite, considered an opportunistic agent, is able to induce gastrointestinal malignancies in humans. In order to add new arguments for a probable association between cryptosporidiosis and digestive human cancer, the main aim of this study is to determine prevalence and to identify species of Cryptosporidium among a French digestive cancer population.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Groupement des Hôpitaux de l'Institut Catholique de Lille, Lomme, Nord, France
Contact Details
Name: Bertrand Nunes, MD
Affiliation: GHICL
Role: STUDY_DIRECTOR
Name: Gabriela Certad, MD, PhD
Affiliation: GHICL
Role: PRINCIPAL_INVESTIGATOR
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