Spots Global Cancer Trial Database for Investigation of the Role of the Microbiome in the Pathogenesis of Colorectal Adenoma and Carcinoma
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Trial Identification
Brief Title: Investigation of the Role of the Microbiome in the Pathogenesis of Colorectal Adenoma and Carcinoma
Official Title: Investigation of the Role of the Microbiome in the Pathogenesis of Colorectal Adenoma and Carcinoma
Study ID: NCT02947607
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study is the investigation of new host-microbiome interactions promoting adenoma formation and adenocarcinoma progression. For that purpose, the investigators will collect saliva, stool and colon biopsy specimens from patients referred to colonoscopy or surgical resection of colorectal tumor. Besides, a questionnaire about diet, lifestyle and medical history will be collected. Sample analysis will involve simultaneous characterization of host and microbiota genomic and transcriptomic components.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Locations
Universitaire Ziekenhuizen Leuven, Leuven, Flemish Brabant, Belgium
Academisch Medisch Centrum, Amsterdam, , Netherlands
Contact Details
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