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Spots Global Cancer Trial Database for EMD 525797 in Colorectal and Ovarian Cancer Patients With Liver Metastases

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Trial Identification

Brief Title: EMD 525797 in Colorectal and Ovarian Cancer Patients With Liver Metastases

Official Title: A Phase I, Open-label, Dose-escalation Study to Investigate the Safety, Tolerability, PD and PK of EMD 525797 Using DCE-MRI as a PK Measure of Response in Colorectal and Ovarian Cancer Patients With Liver Metastases After Failure of Standard Therapy

Study ID: NCT00848510

Interventions

EMD 525797

Study Description

Brief Summary: This study is intended to test an experimental drug called EMD 525797 (Abituzumab). This drug is not yet approved for sale and has only been tested in a small number of people to date (prior to this study starting another research study was carried out involving 37 healthy volunteers receiving the study drug). Until more is known about this study drug, it can only be used in research studies. This research study is planned to answer important questions about how the study drug is tolerated and how it may work in subjects with ovarian and colorectal cancer which has spread to the liver (i.e. metastatic cancer). The Sponsor (Merck KGaA) of this study is developing the study drug.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Christie Hospital, Manchester, , United Kingdom

Contact Details

Name: Medical Responsible

Affiliation: Merck KGaA, Darmstadt, Germany

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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