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Brief Title: Ph II Trial of a Novel Anti-angiogenic Agent in Combination With Chemotherapy for the Second-line Treatment of Metastatic Colorectal Cancer
Official Title: A Randomized, Double-Blind, Phase II Trial of CT-322 (BMS-844203) Plus Irinotecan, 5-FU and Leucovorin (FOLFIRI) Versus Bevacizumab Plus FOLFIRI as Second-Line Treatment for Metastatic Colorectal Cancer
Study ID: NCT00851045
Brief Summary: The purpose of this study is to determine the efficacy of CT-322 comparative to bevacizumab, both in combination with irinotecan, 5-FU and leucovorin in the second-line treatment of subject with metastatic colorectal cancer
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Acrc/Arizona Clinical Research Center, Inc., Tucson, Arizona, United States
Compassionate Cancer Care Medical Group Inc, Fountain Valley, California, United States
Compassionate Cancer Care Medical Group, Inc, Riverside, California, United States
Sharp Memorial Hospital, San Diego, California, United States
Florida Cancer Specialists, Fort Myers, Florida, United States
Midwest Center For Hematology/Oncology, Joliet, Illinois, United States
Cancer Center Of Kansas, Wichita, Kansas, United States
Gurtler, Jayne, Metairie, Louisiana, United States
Guthrie Clinic, Ltd, Sayre, Pennsylvania, United States
Pharma Resource, East Providence, Rhode Island, United States
Sarah Cannon Research Institute, Nashville, Tennessee, United States
University Of Texas M.D. Anderson Cancer Center, Houston, Texas, United States
Local Institution, Bahia Blanca, Buenos Aires, Argentina
Local Institution, Capital Federal, Buenos Aires, Argentina
Local Institution, Terni, , Italy
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR