Spots Global Cancer Trial Database for Study of LGX818 and Cetuximab or LGX818, BYL719, and Cetuximab in BRAF Mutant Metastatic Colorectal Cancer
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We do not endorse or review these studies in any way.
Trial Identification
Brief Title: Study of LGX818 and Cetuximab or LGX818, BYL719, and Cetuximab in BRAF Mutant Metastatic Colorectal Cancer
Official Title: A Phase Ib/II Multi-center, Open-label, Dose Escalation Study of LGX818 and Cetuximab or LGX818, BYL719, and Cetuximab in Patients With BRAF Mutant Metastatic Colorectal Cancer
Study ID: NCT01719380
Conditions
Study Description
Brief Summary: This study will assess the safety and efficacy of LGX818 when combined with cetuximab or combined with cetuximab and BYL719 in patients with BRAF mutant metastatic colorectal cancer
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Keck Hospital of USC, Los Angeles, California, United States
LAC&USC Medical Center, Los Angeles, California, United States
USC/Norris Comprehensive Cancer Center, Los Angeles, California, United States
Ronald Reagan UCLA Medical Center, Los Angeles, California, United States
UCLA University of California Los Angeles, Los Angeles, California, United States
Westwood Bowyer Clinic, Peter Morton Medical Building, Los Angeles, California, United States
UCLA Hematology Oncology, Santa Monica, California, United States
UCLA Santa Monica Medical Center & Orthopaedic Hospital, Santa Monica, California, United States
Smilow Cancer Hospital at Yale-New Haven, New Haven, Connecticut, United States
Yale University, New Haven, Connecticut, United States
Smilow Cancer Hospital Care Center at North Haven, North Haven, Connecticut, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey, United States
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Tennessee Oncology, PLLC, Dickson, Tennessee, United States
Tennessee Oncology, PLLC, Franklin, Tennessee, United States
Tennessee Oncology, PLLC, Gallatin, Tennessee, United States
Tennessee Oncology, PLLC, Hermitage, Tennessee, United States
Tennessee Oncology, PLLC, Lebanon, Tennessee, United States
Tennessee Oncology, PLLC, Murfreesboro, Tennessee, United States
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
Tennessee Oncology, PLLC, Shelbyville, Tennessee, United States
Tennessee Oncology, PLLC, Smyrna, Tennessee, United States
University of Utah - Huntsman Cancer Institute - PPDS, Salt Lake City, Utah, United States
Huntsman Cancer Hospital, Salt Lake City, Utah, United States
Redwood Health Center - ARUP Lab Draw Location, Salt Lake City, Utah, United States
John A Moran Eye Center, Salt Lake City, Utah, United States
Royal Melbourne Hospital, Parkville, Victoria, Australia
UZ Gasthuisberg, Leuven, Vlaams Brabant, Belgium
Princess Margaret Cancer Centre, Toronto, Ontario, Canada
Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec, Canada
Centre Régional de Lutte Contre Le Cancer Val D'aurelle Paul Lamarque, Montpellier, , France
EDOG - Institut Claudius Regaud - PPDS, Toulouse, , France
University Hospital of Koln, Köln, Nordrhein-westfalen, Germany
Universitätsklinikum Essen, Essen, , Germany
Ospedaliero Universitaria di Modena Policlinico, Modena, , Italy
Pharmacy of National Cancer Center Hospital East, Kashiwa, Chiba, Japan
National Cancer Center Hospital, Chuo-ku, Tokyo, Japan
Samsung Medical Center - PPDS, Gangnam-Gu, Seoul Teugbyeolsi, Korea, Republic of
Asan Medical Center - PPDS, Songpa-Gu, Seoul Teugbyeolsi, Korea, Republic of
Het Nederlands Kanker Instituut Antoni Van Leeuwenhoek Ziekenhuis, Amsterdam, Noord-holland, Netherlands
Erasmus MC, Rotterdam, Zuid-holland, Netherlands
Universitair Medisch Centrum Utrecht, Utrecht, , Netherlands
Oslo Myeloma Center - PPDS, Oslo, , Norway
Instituto de Investigacion Oncologica Vall d'Hebron (VHIO) - EPON, Barcelona, , Spain
Hospital Universitario 12 de Octubre, Madrid, , Spain
Hospital Universitario Virgen del Rocio - PPDS, Sevilla, , Spain
Contact Details
Name: Pfizer CT.gov Call Center
Affiliation: Pfizer
Role: STUDY_DIRECTOR
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