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Spots Global Cancer Trial Database for The Implication of ctDNA in the Recurrence Surveillance of Stage II and III Colorectal Cancer

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Trial Identification

Brief Title: The Implication of ctDNA in the Recurrence Surveillance of Stage II and III Colorectal Cancer

Official Title: The Implication of Plasma Circulating Tumor DNA (ctDNA) in the Recurrence Surveillance of Stage II and III Colorectal Cancer: a Prospective Study

Study ID: NCT03416478

Interventions

ctDNA test

Study Description

Brief Summary: This study is to evaluate circulating tumor DNA (ctDNA) as a predictive and surveillant method for tumor recurrence in stage II and III colorectal cancer (CRC).

Detailed Description: This study will evaluate circulating tumor DNA (ctDNA) as a prognostic marker and as a monitor of a short-term disease recurrence in surgical resective stage II and stage III colorectal cancer (CRC). The investigators will recruit newly diagnosed CRC patients, systematically collect their blood samples at the following time point: before surgery, one week after surgery, every three months for the first year and every six months for the second year, which are coincidence with the recommended clinical follow-up. Patients' outcome and survival will be tracked. These study will permit assessment of ctDNA as a predictive and surveillant method for a short-term (two years) tumor recurrence in comparison with other parameters.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

the Sixth Affiliated Hospital, Sun Yet-sen University, Guangzhou, , China

Contact Details

Name: Xiaojian Wu, MD, PhD

Affiliation: Sixth Affiliated Hospital, Sun Yet-sen University

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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