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Brief Title: The Swedish Study of Liver Transplantation for Non-resectable Colorectal Cancer Metastases
Official Title: A Randomized Controlled, Open-label, Multicentre Study Evaluating if Liver Transplantation With Liver Grafts From Extended Criteria Donors Not Utilised for Approved Indications Increases Overall Survival in Patients With Non-resectable Isolated Liver Metastases From Colorectal Metastases, in Comparison With Best Alternative Care
Study ID: NCT04161092
Brief Summary: To evaluate if the addition of liver transplantation primarily utilizing liver grafts from extended criteria donors not utilized for approved indications to conventional treatment of non-resectable/ non-abatable colorectal liver metastases (CLM) increases overall survival compared to best alternative care.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Transplant Institute, Sahlgrenska University Hospital, Gothenburg, , Sweden
Transplantation Unit, Karolinska University Hospital, Stockholm, , Sweden
Name: Per G Lindner, MD, PhD
Affiliation: Transplant Institute, Sahlgrenska University Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Carl Jorns, MD, PhD
Affiliation: Transplantation Unit, Karolinska University Hospital
Role: STUDY_DIRECTOR