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Brief Title: S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer
Official Title: Randomized Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer
Study ID: NCT02164916
Brief Summary: This randomized phase II trial studies how well irinotecan hydrochloride and cetuximab with or without vemurafenib works in treating patients with colorectal cancer that has spread to nearby tissue or lymph nodes, that has spread to other places in the body, or cannot be removed by surgery. Irinotecan hydrochloride and vemurafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as cetuximab, may block the ability of tumor cells to grow and spread. It is not yet known whether irinotecan hydrochloride and cetuximab are more effective with or without vemurafenib in treating colorectal cancer.
Detailed Description: PRIMARY OBJECTIVES: I. To evaluate the progression-free survival (PFS) of v-raf murine sarcoma viral oncogene homolog B (BRAF) mutant metastatic colorectal cancer patients treated with irinotecan (irinotecan hydrochloride), cetuximab, and vemurafenib, compared to a control arm of irinotecan and cetuximab. SECONDARY OBJECTIVES: I. To evaluate the frequency and severity of toxicity associated with each of the treatment arms in this patient population. TERTIARY OBJECTIVES: I. To evaluate overall survival (OS) in treatment Arms 1 and 2. II. To evaluate the overall response rate (ORR), including confirmed and unconfirmed, complete and partial response, in treatment Arms 1 and 2 in the subset of patients with measurable disease. III. To estimate rates of OS, ORR, and PFS in patients who register to Arm 3 after disease progression on Arm 1. IV. To evaluate low-frequency Kirsten rat sarcoma viral oncogene homolog (KRAS) or neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) mutations as detected by high-depth sequencing as predictive biomarkers of efficacy. V. To evaluate phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (PIK3CA) pathway activation through PIK3CA mutations or phosphatase and tensin homolog (PTEN) protein loss as a predictive biomarker of innate resistance to this regimen. VI. To evaluate gene expression signatures from screened patients with v-raf murine sarcoma viral oncogene homolog B wild type (BRAFWT) and BRAFV600E tumors. VII. To provide validation of BRAF immunohistochemistry (IHC) using complementary sequencing methodology from screened patients with BRAFWT and BRAFV600E tumors. VIII. To confirm the estimated sensitivity of detectable BRAF V600E circulating cell-free deoxyribonucleic acid (DNA) as a non-invasive biomarker for BRAF V600E mutation as detected by IHC in the primary tumor. IX. To correlate radiographic tumor response with change in quantification of BRAFV600E alleles in circulating cell-free DNA. X. To monitor for known mechanism of acquired resistance to epidermal growth factor receptor (EGFR) inhibition in circulating cell-free DNA (KRAS, NRAS mutations). OUTLINE: Patients are randomized to 1 of 2 treatment arms. ARM I: Patients receive cetuximab intravenously (IV) and irinotecan hydrochloride IV on days 1 and 14. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients with disease progression may cross over to Arm II. ARM II: Patients receive cetuximab and irinotecan hydrochloride as in Arm I and vemurafenib orally (PO) twice daily (BID) on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. After completion of study treatment, patients are followed up every 2-6 months for 3 years.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Anchorage Radiation Therapy Center, Anchorage, Alaska, United States
Alaska Breast Care and Surgery LLC, Anchorage, Alaska, United States
Alaska Oncology and Hematology LLC, Anchorage, Alaska, United States
Alaska Regional Hospital, Anchorage, Alaska, United States
Alaska Women's Cancer Care, Anchorage, Alaska, United States
Anchorage Oncology Centre, Anchorage, Alaska, United States
Katmai Oncology Group, Anchorage, Alaska, United States
Providence Alaska Medical Center, Anchorage, Alaska, United States
Fairbanks Memorial Hospital, Fairbanks, Alaska, United States
University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona, United States
University of Arizona Cancer Center-North Campus, Tucson, Arizona, United States
The University of Arizona Medical Center-University Campus, Tucson, Arizona, United States
Mercy Cancer Center-Hot Springs, Hot Springs, Arkansas, United States
Fowler Family Center for Cancer Care, Jonesboro, Arkansas, United States
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
Veteran's Administration Medical Center, Little Rock, Arkansas, United States
Kaiser Permanente-Anaheim, Anaheim, California, United States
Kaiser Permanente-Deer Valley Medical Center, Antioch, California, United States
Sutter Auburn Faith Hospital, Auburn, California, United States
Sutter Cancer Centers Radiation Oncology Services-Auburn, Auburn, California, United States
Kaiser Permanente-Baldwin Park, Baldwin Park, California, United States
Kaiser Permanente-Bellflower, Bellflower, California, United States
Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California, United States
Mills - Peninsula Hospitals, Burlingame, California, United States
Sutter Cancer Centers Radiation Oncology Services-Cameron Park, Cameron Park, California, United States
Eden Hospital Medical Center, Castro Valley, California, United States
Sutter Davis Hospital, Davis, California, United States
City of Hope Comprehensive Cancer Center, Duarte, California, United States
Epic Care-Dublin, Dublin, California, United States
Bay Area Breast Surgeons Inc, Emeryville, California, United States
Epic Care Partners in Cancer Care, Emeryville, California, United States
Kaiser Permanente Hospital, Fontana, California, United States
Kaiser Permanente-Fremont, Fremont, California, United States
Kaiser Permanente, Fresno, California, United States
Marin Cancer Care Inc, Greenbrae, California, United States
Marin General Hospital, Greenbrae, California, United States
Kaiser Permanente - Harbor City, Harbor City, California, United States
Kaiser Permanente-Irvine, Irvine, California, United States
Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States
Los Angeles County-USC Medical Center, Los Angeles, California, United States
USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States
Kaiser Permanente-Cadillac, Los Angeles, California, United States
Contra Costa Regional Medical Center, Martinez, California, United States
Fremont - Rideout Cancer Center, Marysville, California, United States
Memorial Medical Center, Modesto, California, United States
Kaiser Permanente-Modesto, Modesto, California, United States
Palo Alto Medical Foundation-Camino Division, Mountain View, California, United States
Palo Alto Medical Foundation-Gynecologic Oncology, Mountain View, California, United States
Sutter Cancer Research Consortium, Novato, California, United States
Alta Bates Summit Medical Center - Summit Campus, Oakland, California, United States
Bay Area Tumor Institute, Oakland, California, United States
Hematology and Oncology Associates-Oakland, Oakland, California, United States
Kaiser Permanente Oakland-Broadway, Oakland, California, United States
Kaiser Permanente-Oakland, Oakland, California, United States
UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California, United States
Palo Alto Medical Foundation Health Care, Palo Alto, California, United States
Kaiser Permanente - Panorama City, Panorama City, California, United States
Keck Medical Center of USC Pasadena, Pasadena, California, United States
PCR Oncology, Pismo Beach, California, United States
Kaiser Permanente-Rancho Cordova Cancer Center, Rancho Cordova, California, United States
Kaiser Permanente-Redwood City, Redwood City, California, United States
Kaiser Permanente-Richmond, Richmond, California, United States
Kaiser Permanente-Riverside, Riverside, California, United States
Rohnert Park Cancer Center, Rohnert Park, California, United States
Kaiser Permanente-Roseville, Roseville, California, United States
Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California, United States
Sutter Roseville Medical Center, Roseville, California, United States
The Permanente Medical Group-Roseville Radiation Oncology, Roseville, California, United States
Sutter General Hospital, Sacramento, California, United States
University of California Davis Comprehensive Cancer Center, Sacramento, California, United States
Kaiser Permanente-South Sacramento, Sacramento, California, United States
South Sacramento Cancer Center, Sacramento, California, United States
Kaiser Permanente - Sacramento, Sacramento, California, United States
Salinas Valley Memorial, Salinas, California, United States
Kaiser Permanente-San Diego Mission, San Diego, California, United States
Kaiser Permanente-San Diego Zion, San Diego, California, United States
California Pacific Medical Center-Pacific Campus, San Francisco, California, United States
Kaiser Permanente-San Francisco, San Francisco, California, United States
UCSF Medical Center-Mount Zion, San Francisco, California, United States
UCSF Medical Center-Mission Bay, San Francisco, California, United States
Kaiser Permanente-Santa Teresa-San Jose, San Jose, California, United States
Kaiser Permanente San Leandro, San Leandro, California, United States
Kaiser Permanente-San Marcos, San Marcos, California, United States
Kaiser Permanente-San Rafael, San Rafael, California, United States
Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California, United States
Palo Alto Medical Foundation-Santa Cruz, Santa Cruz, California, United States
Kaiser Permanente-Santa Rosa, Santa Rosa, California, United States
Sutter Pacific Medical Foundation, Santa Rosa, California, United States
Kaiser Permanente Cancer Treatment Center, South San Francisco, California, United States
Kaiser Permanente-South San Francisco, South San Francisco, California, United States
Kaiser Permanente-Stockton, Stockton, California, United States
Palo Alto Medical Foundation-Sunnyvale, Sunnyvale, California, United States
Gene Upshaw Memorial Tahoe Forest Cancer Center, Truckee, California, United States
Sutter Cancer Centers Radiation Oncology Services-Vacaville, Vacaville, California, United States
Kaiser Permanente Medical Center-Vacaville, Vacaville, California, United States
Kaiser Permanente-Vallejo, Vallejo, California, United States
Sutter Solano Medical Center/Cancer Center, Vallejo, California, United States
Kaiser Permanente-Walnut Creek, Walnut Creek, California, United States
Kaiser Permanente, Woodland Hills, California, United States
Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado, United States
The Medical Center of Aurora, Aurora, Colorado, United States
University of Colorado Cancer Center - Anschutz Cancer Pavilion, Aurora, Colorado, United States
Boulder Community Hospital, Boulder, Colorado, United States
Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado, United States
Penrose-Saint Francis Healthcare, Colorado Springs, Colorado, United States
Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado, United States
Memorial Hospital Colorado Springs, Colorado Springs, Colorado, United States
Denver Health Medical Center, Denver, Colorado, United States
Porter Adventist Hospital, Denver, Colorado, United States
Colorado Blood Cancer Institute, Denver, Colorado, United States
Presbyterian - Saint Lukes Medical Center - Health One, Denver, Colorado, United States
Rocky Mountain Cancer Centers-Midtown, Denver, Colorado, United States
SCL Health Saint Joseph Hospital, Denver, Colorado, United States
Rocky Mountain Cancer Centers-Rose, Denver, Colorado, United States
Rose Medical Center, Denver, Colorado, United States
Colorado Cancer Research Program NCORP, Denver, Colorado, United States
Mercy Medical Center, Durango, Colorado, United States
Southwest Oncology PC, Durango, Colorado, United States
Comprehensive Cancer Care and Research Institute of Colorado LLC, Englewood, Colorado, United States
Swedish Medical Center, Englewood, Colorado, United States
Poudre Valley Hospital, Fort Collins, Colorado, United States
Mountain Blue Cancer Care Center, Golden, Colorado, United States
National Jewish Health-Western Hematology Oncology, Golden, Colorado, United States
North Colorado Medical Center, Greeley, Colorado, United States
Rocky Mountain Cancer Centers-Greenwood Village, Greenwood Village, Colorado, United States
Rocky Mountain Cancer Centers-Lakewood, Lakewood, Colorado, United States
Saint Anthony Hospital, Lakewood, Colorado, United States
Rocky Mountain Cancer Centers-Littleton, Littleton, Colorado, United States
Littleton Adventist Hospital, Littleton, Colorado, United States
Rocky Mountain Cancer Centers-Sky Ridge, Lone Tree, Colorado, United States
Sky Ridge Medical Center, Lone Tree, Colorado, United States
Longmont United Hospital, Longmont, Colorado, United States
Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado, United States
McKee Medical Center, Loveland, Colorado, United States
Parker Adventist Hospital, Parker, Colorado, United States
Rocky Mountain Cancer Centers-Parker, Parker, Colorado, United States
Saint Mary Corwin Medical Center, Pueblo, Colorado, United States
Rocky Mountain Cancer Centers - Pueblo, Pueblo, Colorado, United States
Rocky Mountain Cancer Centers-Thornton, Thornton, Colorado, United States
SCL Health Lutheran Medical Center, Wheat Ridge, Colorado, United States
Smilow Cancer Hospital-Derby Care Center, Derby, Connecticut, United States
Smilow Cancer Hospital Care Center-Fairfield, Fairfield, Connecticut, United States
Greenwich Hospital, Greenwich, Connecticut, United States
Medical Oncology and Hematology Group PC-Guilford, Guilford, Connecticut, United States
Smilow Cancer Hospital Care Center at Saint Francis, Hartford, Connecticut, United States
Middlesex Hospital, Middletown, Connecticut, United States
Yale University, New Haven, Connecticut, United States
Yale-New Haven Hospital North Haven Medical Center, North Haven, Connecticut, United States
Eastern Connecticut Hematology and Oncology Associates, Norwich, Connecticut, United States
Smilow Cancer Hospital-Orange Care Center, Orange, Connecticut, United States
Charlotte Hungerford Hospital Center for Cancer Care, Torrington, Connecticut, United States
Smilow Cancer Hospital Care Center-Trumbull, Trumbull, Connecticut, United States
Smilow Cancer Hospital-Waterbury Care Center, Waterbury, Connecticut, United States
Beebe Medical Center, Lewes, Delaware, United States
Christiana Gynecologic Oncology LLC, Newark, Delaware, United States
Delaware Clinical and Laboratory Physicians PA, Newark, Delaware, United States
Helen F Graham Cancer Center, Newark, Delaware, United States
Medical Oncology Hematology Consultants PA, Newark, Delaware, United States
Regional Hematology and Oncology PA, Newark, Delaware, United States
Christiana Care Health System-Christiana Hospital, Newark, Delaware, United States
Beebe Health Campus, Rehoboth Beach, Delaware, United States
Nanticoke Memorial Hospital, Seaford, Delaware, United States
Christiana Care Health System-Wilmington Hospital, Wilmington, Delaware, United States
Florida Hospital Cancer Institute Altamonte, Altamonte Springs, Florida, United States
University of Florida, Gainesville, Florida, United States
Florida Hospital Kissimmee, Kissimmee, Florida, United States
Mount Sinai Medical Center, Miami Beach, Florida, United States
Florida Hospital Orlando, Orlando, Florida, United States
Florida Urology Associates-Orlando, Orlando, Florida, United States
UF Cancer Center at Orlando Health, Orlando, Florida, United States
Florida Hospital East Orlando, Orlando, Florida, United States
Florida Hospital Cancer Institute Winter Park, Winter Park, Florida, United States
Northside Hospital, Atlanta, Georgia, United States
John B Amos Cancer Center, Columbus, Georgia, United States
Memorial University Medical Center, Savannah, Georgia, United States
Summit Cancer Care-Memorial, Savannah, Georgia, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah, Georgia, United States
Low Country Cancer Care Associates PC, Savannah, Georgia, United States
Hawaii Oncology Inc-Pali Momi, 'Aiea, Hawaii, United States
Pali Momi Medical Center, 'Aiea, Hawaii, United States
The Cancer Center of Hawaii-Leeward, 'Ewa Beach, Hawaii, United States
Hawaii Cancer Care Inc-POB II, Honolulu, Hawaii, United States
Queen's Medical Center, Honolulu, Hawaii, United States
Straub Clinic and Hospital, Honolulu, Hawaii, United States
University of Hawaii Cancer Center, Honolulu, Hawaii, United States
Hawaii Cancer Care Inc-Liliha, Honolulu, Hawaii, United States
Hawaii Oncology Inc-Kuakini, Honolulu, Hawaii, United States
Kuakini Medical Center, Honolulu, Hawaii, United States
The Cancer Center of Hawaii-Liliha, Honolulu, Hawaii, United States
Kaiser Permanente Moanalua Medical Center, Honolulu, Hawaii, United States
Kapiolani Medical Center for Women and Children, Honolulu, Hawaii, United States
Wilcox Memorial Hospital and Kauai Medical Clinic, Lihue, Hawaii, United States
Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho, United States
Saint Luke's Mountain States Tumor Institute, Boise, Idaho, United States
Saint Luke's Mountain States Tumor Institute - Fruitland, Fruitland, Idaho, United States
Saint Luke's Mountain States Tumor Institute - Meridian, Meridian, Idaho, United States
Saint Luke's Mountain States Tumor Institute - Nampa, Nampa, Idaho, United States
Saint Luke's Mountain States Tumor Institute-Twin Falls, Twin Falls, Idaho, United States
Rush - Copley Medical Center, Aurora, Illinois, United States
Saint Joseph Medical Center, Bloomington, Illinois, United States
Illinois CancerCare-Bloomington, Bloomington, Illinois, United States
Illinois CancerCare-Canton, Canton, Illinois, United States
Memorial Hospital of Carbondale, Carbondale, Illinois, United States
Illinois CancerCare-Carthage, Carthage, Illinois, United States
Centralia Oncology Clinic, Centralia, Illinois, United States
Northwestern University, Chicago, Illinois, United States
John H Stroger Jr Hospital of Cook County, Chicago, Illinois, United States
University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States
Carle on Vermilion, Danville, Illinois, United States
Cancer Care Center of Decatur, Decatur, Illinois, United States
Decatur Memorial Hospital, Decatur, Illinois, United States
Carle Physician Group-Effingham, Effingham, Illinois, United States
Crossroads Cancer Center, Effingham, Illinois, United States
Illinois CancerCare-Eureka, Eureka, Illinois, United States
NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois, United States
Illinois CancerCare-Galesburg, Galesburg, Illinois, United States
Western Illinois Cancer Treatment Center, Galesburg, Illinois, United States
NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois, United States
NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois, United States
Joliet Oncology-Hematology Associates Limited, Joliet, Illinois, United States
Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois, United States
Illinois CancerCare-Macomb, Macomb, Illinois, United States
Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois, United States
Loyola University Medical Center, Maywood, Illinois, United States
Good Samaritan Regional Health Center, Mount Vernon, Illinois, United States
Edward Hospital/Cancer Center, Naperville, Illinois, United States
UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois, United States
Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois, United States
Radiation Oncology of Northern Illinois, Ottawa, Illinois, United States
Illinois CancerCare-Pekin, Pekin, Illinois, United States
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center, Pekin, Illinois, United States
Methodist Medical Center of Illinois, Peoria, Illinois, United States
Illinois CancerCare-Peoria, Peoria, Illinois, United States
OSF Saint Francis Radiation Oncology at Peoria Cancer Center, Peoria, Illinois, United States
OSF Saint Francis Medical Center, Peoria, Illinois, United States
Illinois CancerCare-Peru, Peru, Illinois, United States
Valley Radiation Oncology, Peru, Illinois, United States
Edward Hospital/Cancer Center?Plainfield, Plainfield, Illinois, United States
Illinois CancerCare-Princeton, Princeton, Illinois, United States
North Shore Medical Center, Skokie, Illinois, United States
Central Illinois Hematology Oncology Center, Springfield, Illinois, United States
Southern Illinois University School of Medicine, Springfield, Illinois, United States
Springfield Clinic, Springfield, Illinois, United States
Memorial Medical Center, Springfield, Illinois, United States
Cancer Care Specialists of Illinois-Swansea, Swansea, Illinois, United States
Carle Cancer Center, Urbana, Illinois, United States
The Carle Foundation Hospital, Urbana, Illinois, United States
Rush-Copley Healthcare Center, Yorkville, Illinois, United States
Franciscan Saint Anthony Health-Michigan City, Michigan City, Indiana, United States
Woodland Cancer Care Center, Michigan City, Indiana, United States
Memorial Regional Cancer Center Day Road, Mishawaka, Indiana, United States
Reid Health, Richmond, Indiana, United States
Memorial Hospital of South Bend, South Bend, Indiana, United States
Northern Indiana Cancer Research Consortium, South Bend, Indiana, United States
Porter Memorial Hospital, Valparaiso, Indiana, United States
Mary Greeley Medical Center, Ames, Iowa, United States
McFarland Clinic PC-William R Bliss Cancer Center, Ames, Iowa, United States
McFarland Clinic PC-Boone, Boone, Iowa, United States
Medical Oncology and Hematology Associates-West Des Moines, Clive, Iowa, United States
Mercy Cancer Center-West Lakes, Clive, Iowa, United States
Alegent Health Mercy Hospital, Council Bluffs, Iowa, United States
Greater Regional Medical Center, Creston, Iowa, United States
Medical Oncology and Hematology Associates-Laurel, Des Moines, Iowa, United States
Mercy Medical Center - Des Moines, Des Moines, Iowa, United States
McFarland Clinic PC-Trinity Cancer Center, Fort Dodge, Iowa, United States
McFarland Clinic PC-Jefferson, Jefferson, Iowa, United States
McFarland Clinic PC-Marshalltown, Marshalltown, Iowa, United States
Mercy Medical Center - North Iowa, Mason City, Iowa, United States
Story County Medical Center-South Campus, Nevada, Iowa, United States
Siouxland Regional Cancer Center, Sioux City, Iowa, United States
Mercy Medical Center-West Lakes, West Des Moines, Iowa, United States
Cancer Center of Kansas - Chanute, Chanute, Kansas, United States
Cancer Center of Kansas - Dodge City, Dodge City, Kansas, United States
Cancer Center of Kansas - El Dorado, El Dorado, Kansas, United States
Newman Regional Health, Emporia, Kansas, United States
Cancer Center of Kansas - Fort Scott, Fort Scott, Kansas, United States
Saint Catherine Hospital, Garden City, Kansas, United States
Saint Rose Ambulatory and Surgery Center, Great Bend, Kansas, United States
Hays Medical Center, Hays, Kansas, United States
Cancer Center of Kansas-Independence, Independence, Kansas, United States
University of Kansas Cancer Center-West, Kansas City, Kansas, United States
University of Kansas Cancer Center, Kansas City, Kansas, United States
Cancer Center of Kansas-Kingman, Kingman, Kansas, United States
Lawrence Memorial Hospital, Lawrence, Kansas, United States
Cancer Center of Kansas-Liberal, Liberal, Kansas, United States
Cancer Center of Kansas - Newton, Newton, Kansas, United States
Olathe Medical Center, Olathe, Kansas, United States
University of Kansas Cancer Center-Overland Park, Overland Park, Kansas, United States
Cancer Center of Kansas - Parsons, Parsons, Kansas, United States
Via Christi Hospital-Pittsburg, Pittsburg, Kansas, United States
Cancer Center of Kansas - Pratt, Pratt, Kansas, United States
Cancer Center of Kansas - Salina, Salina, Kansas, United States
Salina Regional Health Center, Salina, Kansas, United States
Saint Francis Hospital and Medical Center - Topeka, Topeka, Kansas, United States
Cancer Center of Kansas - Wellington, Wellington, Kansas, United States
Associates In Womens Health, Wichita, Kansas, United States
Cancer Center of Kansas-Wichita Medical Arts Tower, Wichita, Kansas, United States
Cancer Center of Kansas - Wichita, Wichita, Kansas, United States
Via Christi Regional Medical Center, Wichita, Kansas, United States
Wichita NCI Community Oncology Research Program, Wichita, Kansas, United States
Cancer Center of Kansas - Winfield, Winfield, Kansas, United States
Flaget Memorial Hospital, Bardstown, Kentucky, United States
Commonwealth Cancer Center-Corbin, Corbin, Kentucky, United States
Oncology Hematology Care Inc-Crestview, Crestview Hills, Kentucky, United States
Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky, United States
Saint Joseph Hospital East, Lexington, Kentucky, United States
Jewish Hospital, Louisville, Kentucky, United States
Saints Mary and Elizabeth Hospital, Louisville, Kentucky, United States
Jewish Hospital Medical Center Northeast, Louisville, Kentucky, United States
Jewish Hospital Medical Center South, Shepherdsville, Kentucky, United States
Christus Saint Frances Cabrini Hospital, Alexandria, Louisiana, United States
LSU Health Baton Rouge-North Clinic, Baton Rouge, Louisiana, United States
Louisiana Hematology Oncology Associates LLC, Baton Rouge, Louisiana, United States
Medical Oncology LLC, Baton Rouge, Louisiana, United States
Mary Bird Cancer Center/Saint Tammany Parish, Covington, Louisiana, United States
Mary Bird Perkins Cancer Center/Terrebonne General Medical Center, Houma, Louisiana, United States
Ochsner Medical Center Jefferson, New Orleans, Louisiana, United States
Harold Alfond Center for Cancer Care, Augusta, Maine, United States
Eastern Maine Medical Center, Bangor, Maine, United States
Lafayette Family Cancer Center-EMMC, Brewer, Maine, United States
Sinai Hospital of Baltimore, Baltimore, Maryland, United States
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland, United States
Union Hospital of Cecil County, Elkton, Maryland, United States
Northwest Hospital Center, Randallstown, Maryland, United States
Peninsula Regional Medical Center, Salisbury, Maryland, United States
Beverly Hospital, Beverly, Massachusetts, United States
Lahey Hospital and Medical Center, Burlington, Massachusetts, United States
Addison Gilbert Hospital, Gloucester, Massachusetts, United States
Baystate Medical Center, Springfield, Massachusetts, United States
Hickman Cancer Center, Adrian, Michigan, United States
Saint Joseph Mercy Hospital, Ann Arbor, Michigan, United States
University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States
Bronson Battle Creek, Battle Creek, Michigan, United States
McLaren-Bay Region, Bay City, Michigan, United States
Henry Ford Cancer Institute¿Downriver, Brownstown, Michigan, United States
Great Lakes Cancer Institute, Clarkston, Michigan, United States
Henry Ford Macomb Hospital-Clinton Township, Clinton Township, Michigan, United States
Beaumont Hospital-Dearborn, Dearborn, Michigan, United States
Henry Ford Medical Center-Fairlane, Dearborn, Michigan, United States
Wayne State University/Karmanos Cancer Institute, Detroit, Michigan, United States
Henry Ford Hospital, Detroit, Michigan, United States
Saint John Hospital and Medical Center, Detroit, Michigan, United States
Green Bay Oncology - Escanaba, Escanaba, Michigan, United States
Weisberg Cancer Treatment Center, Farmington Hills, Michigan, United States
Hurley Medical Center, Flint, Michigan, United States
Genesys Hurley Cancer Institute, Flint, Michigan, United States
Singh and Arora Hematology Oncology PC, Flint, Michigan, United States
Mercy Health Saint Mary's, Grand Rapids, Michigan, United States
Spectrum Health at Butterworth Campus, Grand Rapids, Michigan, United States
Allegiance Health, Jackson, Michigan, United States
Borgess Medical Center, Kalamazoo, Michigan, United States
Bronson Methodist Hospital, Kalamazoo, Michigan, United States
West Michigan Cancer Center, Kalamazoo, Michigan, United States
McLaren-Greater Lansing, Lansing, Michigan, United States
Sparrow Hospital, Lansing, Michigan, United States
McLaren Cancer Institute-Lapeer Region, Lapeer, Michigan, United States
Saint Mary Mercy Hospital, Livonia, Michigan, United States
Monroe Cancer Center, Monroe, Michigan, United States
Toledo Clinic Cancer Centers-Monroe, Monroe, Michigan, United States
McLaren Cancer Institute-Macomb, Mount Clemens, Michigan, United States
McLaren Cancer Institute-Central Michigan, Mount Pleasant, Michigan, United States
Mercy Health Mercy Campus, Muskegon, Michigan, United States
Lakeland Community Hospital, Niles, Michigan, United States
Assarian Cancer Center, Novi, Michigan, United States
Henry Ford Medical Center-Columbus, Novi, Michigan, United States
McLaren Cancer Institute-Northern Michigan, Petoskey, Michigan, United States
Saint Joseph Mercy Oakland, Pontiac, Michigan, United States
Lake Huron Medical Center, Port Huron, Michigan, United States
Spectrum Health Reed City Hospital, Reed City, Michigan, United States
Saint Mary's of Michigan, Saginaw, Michigan, United States
Lakeland Hospital, Saint Joseph, Michigan, United States
Marie Yeager Cancer Center, Saint Joseph, Michigan, United States
Providence Hospital-Southfield Cancer Center, Southfield, Michigan, United States
Munson Medical Center, Traverse City, Michigan, United States
Saint John Macomb-Oakland Hospital, Warren, Michigan, United States
Henry Ford West Bloomfield Hospital, West Bloomfield, Michigan, United States
Sanford Clinic North-Bemidgi, Bemidji, Minnesota, United States
Essentia Health Saint Joseph's Medical Center, Brainerd, Minnesota, United States
Fairview Ridges Hospital, Burnsville, Minnesota, United States
Mercy Hospital, Coon Rapids, Minnesota, United States
Essentia Health Cancer Center, Duluth, Minnesota, United States
Essentia Health Saint Mary's Medical Center, Duluth, Minnesota, United States
Miller-Dwan Hospital, Duluth, Minnesota, United States
Saint Luke's Hospital of Duluth, Duluth, Minnesota, United States
Fairview-Southdale Hospital, Edina, Minnesota, United States
Lake Region Healthcare Corporation-Cancer Care, Fergus Falls, Minnesota, United States
Unity Hospital, Fridley, Minnesota, United States
Hutchinson Area Health Care, Hutchinson, Minnesota, United States
Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota, United States
Saint John's Hospital - Healtheast, Maplewood, Minnesota, United States
Abbott-Northwestern Hospital, Minneapolis, Minnesota, United States
Hennepin County Medical Center, Minneapolis, Minnesota, United States
Health Partners Inc, Minneapolis, Minnesota, United States
New Ulm Medical Center, New Ulm, Minnesota, United States
North Memorial Medical Health Center, Robbinsdale, Minnesota, United States
Mayo Clinic, Rochester, Minnesota, United States
Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud, Minnesota, United States
Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota, United States
Regions Hospital, Saint Paul, Minnesota, United States
United Hospital, Saint Paul, Minnesota, United States
Saint Francis Regional Medical Center, Shakopee, Minnesota, United States
Lakeview Hospital, Stillwater, Minnesota, United States
Ridgeview Medical Center, Waconia, Minnesota, United States
Rice Memorial Hospital, Willmar, Minnesota, United States
Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota, United States
Hattiesburg Clinic - Hematology/Oncology Clinic, Hattiesburg, Mississippi, United States
Forrest General Hospital / Cancer Center, Hattiesburg, Mississippi, United States
University of Mississippi Medical Center, Jackson, Mississippi, United States
Singing River Hospital, Pascagoula, Mississippi, United States
Central Care Cancer Center-Carrie J Babb Cancer Center, Bolivar, Missouri, United States
Parkland Health Center-Bonne Terre, Bonne Terre, Missouri, United States
CoxHealth Cancer Center, Branson, Missouri, United States
Saint Francis Medical Center, Cape Girardeau, Missouri, United States
Southeast Cancer Center, Cape Girardeau, Missouri, United States
Saint Luke's Hospital, Chesterfield, Missouri, United States
Barnes-Jewish West County Hospital, Creve Coeur, Missouri, United States
Capital Region Medical Center-Goldschmidt Cancer Center, Jefferson City, Missouri, United States
Freeman Health System, Joplin, Missouri, United States
Mercy Hospital-Joplin, Joplin, Missouri, United States
Truman Medical Center, Kansas City, Missouri, United States
The University of Kansas Cancer Center-South, Kansas City, Missouri, United States
The University of Kansas Cancer Center-North, Kansas City, Missouri, United States
The University of Kansas Cancer Center-Lee's Summit, Lee's Summit, Missouri, United States
Delbert Day Cancer Institute at PCRMC, Rolla, Missouri, United States
Saint John's Clinic-Rolla-Cancer and Hematology, Rolla, Missouri, United States
Saint Louis Cancer and Breast Institute-South City, Saint Louis, Missouri, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Missouri Baptist Medical Center, Saint Louis, Missouri, United States
Mercy Hospital Saint Louis, Saint Louis, Missouri, United States
Siteman Cancer Center - Saint Peters, Saint Peters, Missouri, United States
Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri, United States
Mercy Hospital Springfield, Springfield, Missouri, United States
CoxHealth South Hospital, Springfield, Missouri, United States
Missouri Baptist Sullivan Hospital, Sullivan, Missouri, United States
Missouri Baptist Outpatient Center-Sunset Hills, Sunset Hills, Missouri, United States
CHI Health Saint Francis, Grand Island, Nebraska, United States
Heartland Hematology and Oncology, Kearney, Nebraska, United States
CHI Health Good Samaritan, Kearney, Nebraska, United States
Nebraska Hematology and Oncology, Lincoln, Nebraska, United States
Nebraska Cancer Research Center, Lincoln, Nebraska, United States
Saint Elizabeth Regional Medical Center, Lincoln, Nebraska, United States
Southeast Nebraska Cancer Center, Lincoln, Nebraska, United States
Faith Regional Medical Offices West, Norfolk, Nebraska, United States
Great Plains Regional Medical Center, North Platte, Nebraska, United States
Missouri Valley Cancer Consortium, Omaha, Nebraska, United States
Alegent Health Immanuel Medical Center, Omaha, Nebraska, United States
Hemotology and Oncology Consultants PC, Omaha, Nebraska, United States
Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska, United States
Oncology Hematology West, Omaha, Nebraska, United States
Alegent Health Lakeside Hospital, Omaha, Nebraska, United States
Oncology Hematology West PC, Omaha, Nebraska, United States
Creighton University Medical Center, Omaha, Nebraska, United States
Midlands Community Hospital, Papillion, Nebraska, United States
Regional West Medical Center, Scottsbluff, Nebraska, United States
Cancer and Blood Specialists-Henderson, Henderson, Nevada, United States
Comprehensive Cancer Centers of Nevada - Henderson, Henderson, Nevada, United States
Las Vegas Cancer Center-Henderson, Henderson, Nevada, United States
21st Century Oncology - Henderson, Henderson, Nevada, United States
Comprehensive Cancer Centers of Nevada-Southeast Henderson, Henderson, Nevada, United States
Cancer and Blood Specialists-Shadow, Las Vegas, Nevada, United States
Radiation Oncology Centers of Nevada Central, Las Vegas, Nevada, United States
21st Century Oncology, Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway, Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-San Martin, Las Vegas, Nevada, United States
Radiation Oncology Centers of Nevada Southeast, Las Vegas, Nevada, United States
Cancer Therapy and Integrative Medicine, Las Vegas, Nevada, United States
Cancer and Blood Specialists-Tenaya, Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada - Northwest, Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-Tenaya, Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada-Summerlin, Las Vegas, Nevada, United States
Summerlin Hospital Medical Center, Las Vegas, Nevada, United States
Las Vegas Cancer Center-Medical Center, Las Vegas, Nevada, United States
21st Century Oncology - Fort Apache, Las Vegas, Nevada, United States
Cancer and Blood Specialists-Fort Apache, Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills, Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada - Central Valley, Las Vegas, Nevada, United States
21st Century Oncology - Vegas Tenaya, Las Vegas, Nevada, United States
Saint Mary's Regional Medical Center, Reno, Nevada, United States
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States
Norris Cotton Cancer Center-Manchester, Manchester, New Hampshire, United States
Norris Cotton Cancer Center-Nashua, Nashua, New Hampshire, United States
Englewood Hospital and Medical Center, Englewood, New Jersey, United States
Virtua Memorial, Mount Holly, New Jersey, United States
Newark Beth Israel Medical Center, Newark, New Jersey, United States
The Valley Hospital-Luckow Pavilion, Paramus, New Jersey, United States
Valley Hospital, Ridgewood, New Jersey, United States
Sparta Cancer Treatment Center, Sparta, New Jersey, United States
Inspira Medical Center Vineland, Vineland, New Jersey, United States
Virtua Voorhees, Voorhees, New Jersey, United States
Valley Health System-Hematology/Oncology, Westwood, New Jersey, United States
Inspira Medical Center Woodbury, Woodbury, New Jersey, United States
University of New Mexico Cancer Center, Albuquerque, New Mexico, United States
Memorial Medical Center - Las Cruces, Las Cruces, New Mexico, United States
Montefiore Medical Center-Einstein Campus, Bronx, New York, United States
Montefiore Medical Center-Weiler Hospital, Bronx, New York, United States
Montefiore Medical Center - Moses Campus, Bronx, New York, United States
Arnot Ogden Medical Center/Falck Cancer Center, Elmira, New York, United States
Glens Falls Hospital, Glens Falls, New York, United States
Weill Medical College of Cornell University, New York, New York, United States
State University of New York Upstate Medical University, Syracuse, New York, United States
Faxton-Saint Luke's Healthcare, Utica, New York, United States
Randolph Hospital, Asheboro, North Carolina, United States
Asheville Hematology-Oncology Associates, Asheville, North Carolina, United States
Cone Health Cancer Center at Alamance Regional, Burlington, North Carolina, United States
Sampson Radiation Oncology, Clinton, North Carolina, United States
Southeastern Medical Oncology Center-Clinton, Clinton, North Carolina, United States
Duke University Medical Center, Durham, North Carolina, United States
Southeastern Medical Oncology Center-Goldsboro, Goldsboro, North Carolina, United States
Wayne Memorial Hospital, Goldsboro, North Carolina, United States
Wayne Radiation Oncology, Goldsboro, North Carolina, United States
Cone Health Cancer Center, Greensboro, North Carolina, United States
Hendersonville Hematology and Oncology at Pardee, Hendersonville, North Carolina, United States
Margaret R Pardee Memorial Hospital, Hendersonville, North Carolina, United States
Park Ridge Hospital Breast Health Center, Hendersonville, North Carolina, United States
Maria Parham Hospital, Henderson, North Carolina, United States
Onslow Memorial Hospital, Jacksonville, North Carolina, United States
Southeastern Medical Oncology Center-Jacksonville, Jacksonville, North Carolina, United States
Kinston Medical Specialists PA, Kinston, North Carolina, United States
Scotland Memorial Hospital-Laurinburg Cancer Center, Laurinburg, North Carolina, United States
Cone Heath Cancer Center at Mebane, Mebane, North Carolina, United States
Annie Penn Memorial Hospital, Reidsville, North Carolina, United States
Johnston Memorial Hospital, Smithfield, North Carolina, United States
Southeastern Medical Oncology Center-Wilson, Wilson, North Carolina, United States
Sanford Bismarck Medical Center, Bismarck, North Dakota, United States
Essentia Health Cancer Center-South University Clinic, Fargo, North Dakota, United States
Roger Maris Cancer Center, Fargo, North Dakota, United States
Sanford Clinic North-Fargo, Fargo, North Dakota, United States
Sanford Medical Center-Fargo, Fargo, North Dakota, United States
Akron General Medical Center, Akron, Ohio, United States
Strecker Cancer Center-Belpre, Belpre, Ohio, United States
Mercy Medical Center, Canton, Ohio, United States
Dayton Physicians LLC-Miami Valley South, Centerville, Ohio, United States
Miami Valley Hospital South, Centerville, Ohio, United States
Geaugra Hospital, Chardon, Ohio, United States
Adena Regional Medical Center, Chillicothe, Ohio, United States
Oncology Hematology Care Inc-Eden Park, Cincinnati, Ohio, United States
Oncology Hematology Care Inc-Mercy West, Cincinnati, Ohio, United States
University of Cincinnati/Barrett Cancer Center, Cincinnati, Ohio, United States
Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio, United States
Oncology Hematology Care Inc - Anderson, Cincinnati, Ohio, United States
Oncology Hematology Care Inc-Kenwood, Cincinnati, Ohio, United States
Bethesda North Hospital, Cincinnati, Ohio, United States
Oncology Hematology Care Inc-Blue Ash, Cincinnati, Ohio, United States
TriHealth Cancer Institute-Westside, Cincinnati, Ohio, United States
TriHealth Cancer Institute-Anderson, Cincinnati, Ohio, United States
Case Western Reserve University, Cleveland, Ohio, United States
MetroHealth Medical Center, Cleveland, Ohio, United States
Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio, United States
Cleveland Clinic Foundation, Cleveland, Ohio, United States
Columbus Oncology and Hematology Associates Inc, Columbus, Ohio, United States
Riverside Methodist Hospital, Columbus, Ohio, United States
Grant Medical Center, Columbus, Ohio, United States
The Mark H Zangmeister Center, Columbus, Ohio, United States
Mount Carmel Health Center West, Columbus, Ohio, United States
Doctors Hospital, Columbus, Ohio, United States
Good Samaritan Hospital - Dayton, Dayton, Ohio, United States
Miami Valley Hospital, Dayton, Ohio, United States
Dayton Physicians LLC-Samaritan North, Dayton, Ohio, United States
Samaritan North Health Center, Dayton, Ohio, United States
Delaware Health Center-Grady Cancer Center, Delaware, Ohio, United States
Delaware Radiation Oncology, Delaware, Ohio, United States
Grady Memorial Hospital, Delaware, Ohio, United States
Mercy Cancer Center-Elyria, Elyria, Ohio, United States
Oncology Hematology Care Inc-Healthplex, Fairfield, Ohio, United States
Armes Family Cancer Center, Findlay, Ohio, United States
Blanchard Valley Hospital, Findlay, Ohio, United States
Orion Cancer Care, Findlay, Ohio, United States
Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio, United States
Dayton Physicians LLC-Atrium, Franklin, Ohio, United States
Dayton Physicians LLC-Wayne, Greenville, Ohio, United States
Wayne Hospital, Greenville, Ohio, United States
Cleveland Clinic Cancer Center Independence, Independence, Ohio, United States
Greater Dayton Cancer Center, Kettering, Ohio, United States
Kettering Medical Center, Kettering, Ohio, United States
Fairfield Medical Center, Lancaster, Ohio, United States
Saint Rita's Medical Center, Lima, Ohio, United States
Cleveland Clinic Cancer Center Mansfield, Mansfield, Ohio, United States
Marietta Memorial Hospital, Marietta, Ohio, United States
Toledo Clinic Cancer Centers-Maumee, Maumee, Ohio, United States
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center, Maumee, Ohio, United States
Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio, United States
Lake University Ireland Cancer Center, Mentor, Ohio, United States
Southwest General Health Center Ireland Cancer Center, Middleburg Heights, Ohio, United States
Dayton Physicians LLC-Signal Point, Middletown, Ohio, United States
Knox Community Hospital, Mount Vernon, Ohio, United States
Licking Memorial Hospital, Newark, Ohio, United States
Newark Radiation Oncology, Newark, Ohio, United States
Saint Charles Hospital, Oregon, Ohio, United States
University Hospitals Parma Medical Center, Parma, Ohio, United States
Southern Ohio Medical Center, Portsmouth, Ohio, United States
Ireland Cancer Center at Firelands Regional Medical Center, Sandusky, Ohio, United States
North Coast Cancer Care, Sandusky, Ohio, United States
Dayton Physicians LLC-Wilson, Sidney, Ohio, United States
Springfield Regional Cancer Center, Springfield, Ohio, United States
Springfield Regional Medical Center, Springfield, Ohio, United States
Cleveland Clinic Cancer Center Strongsville, Strongsville, Ohio, United States
Flower Hospital, Sylvania, Ohio, United States
Mercy Saint Anne Hospital, Toledo, Ohio, United States
Toledo Clinic Cancer Centers-Toledo, Toledo, Ohio, United States
Dayton Physicians LLC-Upper Valley, Troy, Ohio, United States
Upper Valley Medical Center, Troy, Ohio, United States
University Hospitals Sharon Health Center, Wadsworth, Ohio, United States
South Pointe Hospital, Warrensville Heights, Ohio, United States
University Pointe, West Chester, Ohio, United States
Saint Ann's Hospital, Westerville, Ohio, United States
UH-Seidman Cancer Center at Saint John Medical Center, Westlake, Ohio, United States
Cleveland Clinic Wooster Family Health and Surgery Center, Wooster, Ohio, United States
Wright-Patterson Medical Center, Wright-Patterson Air Force Base, Ohio, United States
Genesis Healthcare System Cancer Care Center, Zanesville, Ohio, United States
Cancer Centers of Southwest Oklahoma Research, Lawton, Oklahoma, United States
Saint Charles Health System, Bend, Oregon, United States
Clackamas Radiation Oncology Center, Clackamas, Oregon, United States
Providence Oncology and Hematology Care Southeast, Clackamas, Oregon, United States
Bay Area Hospital, Coos Bay, Oregon, United States
Providence Newberg Medical Center, Newberg, Oregon, United States
Providence Willamette Falls Medical Center, Oregon City, Oregon, United States
Providence Portland Medical Center, Portland, Oregon, United States
Providence Saint Vincent Medical Center, Portland, Oregon, United States
Kaiser Permanente Northwest, Portland, Oregon, United States
Christiana Care Health System-Concord Health Center, Chadds Ford, Pennsylvania, United States
Geisinger Medical Center, Danville, Pennsylvania, United States
Doylestown Hospital, Doylestown, Pennsylvania, United States
PinnacleHealth Cancer Center-Community Campus, Harrisburg, Pennsylvania, United States
Geisinger Medical Center-Cancer Center Hazleton, Hazleton, Pennsylvania, United States
Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, United States
Geisinger Medical Oncology-Lewisburg, Lewisburg, Pennsylvania, United States
Lewistown Hospital, Lewistown, Pennsylvania, United States
University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania, United States
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States
Phoenixville Hospital, Phoenixville, Pennsylvania, United States
Geisinger Medical Oncology-Pottsville, Pottsville, Pennsylvania, United States
Guthrie Medical Group PC-Robert Packer Hospital, Sayre, Pennsylvania, United States
Hematology and Oncology Associates of North East Pennsylvania, Scranton, Pennsylvania, United States
Geisinger Medical Group, State College, Pennsylvania, United States
Reading Hospital, West Reading, Pennsylvania, United States
Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania, United States
Susquehanna Cancer Center, Williamsport, Pennsylvania, United States
Roper Hospital, Charleston, South Carolina, United States
Charleston Hematology Oncology Associates-Roper, Charleston, South Carolina, United States
Lowcountry Hematology Oncology PA-North Charleston, Charleston, South Carolina, United States
Bon Secours Saint Francis Hospital, Charleston, South Carolina, United States
Charleston Hematology Oncology Associates PA-St. Francis, Charleston, South Carolina, United States
Lowcountry Hematology Oncology PA-West Ashley, Charleston, South Carolina, United States
Greenville Health System Cancer Institute-Easley, Easley, South Carolina, United States
Saint Francis Hospital, Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Andrews, Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Butternut, Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Faris, Greenville, South Carolina, United States
Greenville Memorial Hospital, Greenville, South Carolina, United States
Saint Francis Cancer Center, Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Eastside, Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Greer, Greer, South Carolina, United States
Lowcountry Hematology Oncology PA-Mount Pleasant, Mount Pleasant, South Carolina, United States
Greenville Health System Cancer Institute-Seneca, Seneca, South Carolina, United States
Greenville Health System Cancer Institute-Spartanburg, Spartanburg, South Carolina, United States
Sanford Cancer Center-Oncology Clinic, Sioux Falls, South Dakota, United States
Avera Cancer Institute, Sioux Falls, South Dakota, United States
Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota, United States
Memorial Hospital, Chattanooga, Tennessee, United States
Pulmonary Medicine Center of Chattanooga-Hixson, Hixson, Tennessee, United States
Thompson Cancer Survival Center, Knoxville, Tennessee, United States
Meharry Medical College, Nashville, Tennessee, United States
Memorial GYN Plus, Ooltewah, Tennessee, United States
M D Anderson Cancer Center, Houston, Texas, United States
Scott and White Healthcare Round Rock, Round Rock, Texas, United States
University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States
Scott and White Memorial Hospital, Temple, Texas, United States
Central Vermont Medical Center/National Life Cancer Treatment, Berlin, Vermont, United States
University of Vermont Medical Center, Burlington, Vermont, United States
University of Vermont College of Medicine, Burlington, Vermont, United States
Providence Regional Cancer System-Aberdeen, Aberdeen, Washington, United States
Cancer Care Center at Island Hospital, Anacortes, Washington, United States
MultiCare Auburn Medical Center, Auburn, Washington, United States
Virginia Mason Bainbridge Island Medical Center, Bainbridge Island, Washington, United States
Overlake Hospital Medical Center, Bellevue, Washington, United States
Swedish Cancer Institute-Eastside Oncology Hematology, Bellevue, Washington, United States
PeaceHealth Saint Joseph Medical Center, Bellingham, Washington, United States
Harrison HealthPartners Hematology and Oncology-Bremerton, Bremerton, Washington, United States
Harrison Medical Center, Bremerton, Washington, United States
Highline Medical Center-Main Campus, Burien, Washington, United States
Providence Regional Cancer System-Centralia, Centralia, Washington, United States
Swedish Medical Center-Edmonds, Edmonds, Washington, United States
Saint Elizabeth Hospital, Enumclaw, Washington, United States
Providence Regional Cancer Partnership, Everett, Washington, United States
Virginia Mason Federal Way Medical Center, Federal Way, Washington, United States
Saint Francis Hospital, Federal Way, Washington, United States
Tacoma/Valley Radiation Oncology Centers-Gig Harbor, Gig Harbor, Washington, United States
MultiCare Gig Harbor Medical Park, Gig Harbor, Washington, United States
Swedish Cancer Institute-Issaquah, Issaquah, Washington, United States
Kadlec Clinic Hematology and Oncology, Kennewick, Washington, United States
Northwest Cancer Clinic, Kennewick, Washington, United States
Seattle Cancer Care Alliance at EvergreenHealth, Kirkland, Washington, United States
Providence Regional Cancer System-Lacey, Lacey, Washington, United States
Saint Clare Hospital, Lakewood, Washington, United States
PeaceHealth Saint John Medical Center, Longview, Washington, United States
Virginia Mason Lynnwood Medical Center, Lynnwood, Washington, United States
Skagit Valley Hospital Regional Cancer Care Center, Mount Vernon, Washington, United States
Skagit Valley Hospital, Mount Vernon, Washington, United States
Olympic Medical Center, Port Angeles, Washington, United States
Jefferson Healthcare, Port Townsend, Washington, United States
Harrison HealthPartners Hematology and Oncology-Poulsbo, Poulsbo, Washington, United States
Peninsula Cancer Center, Poulsbo, Washington, United States
MultiCare Good Samaritan Hospital, Puyallup, Washington, United States
Tacoma/Valley Radiation Oncology Centers-Puyallup, Puyallup, Washington, United States
Virginia Mason Medical Center, Seattle, Washington, United States
Minor and James Medical PLLC, Seattle, Washington, United States
Pacific Gynecology Specialists, Seattle, Washington, United States
Swedish Medical Center-Ballard Campus, Seattle, Washington, United States
Fred Hutchinson Cancer Research Center, Seattle, Washington, United States
Seattle Cancer Care Alliance, Seattle, Washington, United States
Group Health Cooperative-Seattle, Seattle, Washington, United States
Swedish Medical Center-First Hill, Seattle, Washington, United States
University of Washington Medical Center, Seattle, Washington, United States
Olympic Medical Cancer Care Center, Sequim, Washington, United States
Providence Regional Cancer System-Shelton, Shelton, Washington, United States
Rockwood Clinic Cancer Treatment Center-Valley, Spokane Valley, Washington, United States
Cancer Care Northwest - Spokane South, Spokane, Washington, United States
Rockwood Cancer Treatment Center-DHEC-Downtown, Spokane, Washington, United States
Spokane Valley Cancer Center-Mayfair, Spokane, Washington, United States
Cancer Care Northwest-Valley, Spokane, Washington, United States
Cancer Care Northwest-North Spokane, Spokane, Washington, United States
Tacoma/Valley Radiation Oncology Centers-Jackson Hall, Tacoma, Washington, United States
Franciscan Research Center-Northwest Medical Plaza, Tacoma, Washington, United States
MultiCare Tacoma General Hospital, Tacoma, Washington, United States
Northwest Medical Specialties PLLC, Tacoma, Washington, United States
Northwest NCI Community Oncology Research Program, Tacoma, Washington, United States
Tacoma/Valley Radiation Oncology Centers-Saint Joe's, Tacoma, Washington, United States
PeaceHealth Southwest Medical Center, Vancouver, Washington, United States
Providence Saint Mary Regional Cancer Center, Walla Walla, Washington, United States
Wenatchee Valley Hospital and Clinics, Wenatchee, Washington, United States
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital, Yakima, Washington, United States
Providence Regional Cancer System-Yelm, Yelm, Washington, United States
West Virginia University Charleston, Charleston, West Virginia, United States
Langlade Hospital and Cancer Center, Antigo, Wisconsin, United States
Marshfield Clinic-Chippewa Center, Chippewa Falls, Wisconsin, United States
Marshfield Clinic Cancer Center at Sacred Heart, Eau Claire, Wisconsin, United States
Green Bay Oncology at Saint Vincent Hospital, Green Bay, Wisconsin, United States
Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin, United States
Green Bay Oncology Limited at Saint Mary's Hospital, Green Bay, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin, United States
Gundersen Lutheran Medical Center, La Crosse, Wisconsin, United States
Holy Family Memorial Hospital, Manitowoc, Wisconsin, United States
Marshfield Clinic, Marshfield, Wisconsin, United States
Wheaton Franciscan Healthcare - Saint Joseph, Milwaukee, Wisconsin, United States
Marshfield Clinic-Minocqua Center, Minocqua, Wisconsin, United States
ProHealth D N Greenwald Center, Mukwonago, Wisconsin, United States
Cancer Center of Western Wisconsin, New Richmond, Wisconsin, United States
ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin, United States
Green Bay Oncology - Oconto Falls, Oconto Falls, Wisconsin, United States
Marshfield Clinic-Rice Lake Center, Rice Lake, Wisconsin, United States
HSHS Saint Nicholas Hospital, Sheboygan, Wisconsin, United States
Marshfield Clinic Cancer Care at Saint Michael's Hospital, Stevens Point, Wisconsin, United States
Green Bay Oncology - Sturgeon Bay, Sturgeon Bay, Wisconsin, United States
ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin, United States
UW Cancer Center at ProHealth Care, Waukesha, Wisconsin, United States
Aspirus Regional Cancer Center, Wausau, Wisconsin, United States
Marshfield Clinic-Wausau Center, Wausau, Wisconsin, United States
Marshfield Clinic - Weston Center, Weston, Wisconsin, United States
Aspirus UW Cancer Center, Wisconsin Rapids, Wisconsin, United States
Marshfield Clinic - Wisconsin Rapids Center, Wisconsin Rapids, Wisconsin, United States
Cheyenne Regional Medical Center-West, Cheyenne, Wyoming, United States
Name: Edmund S Kopetz, M.D.
Affiliation: M.D. Anderson
Role: PRINCIPAL_INVESTIGATOR