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Brief Title: Study of XL092 + Atezolizumab vs Regorafenib in Subjects With Metastatic Colorectal Cancer
Official Title: A Randomized Open-Label Phase 3 Study of XL092 + Atezolizumab vs Regorafenib in Subjects With Metastatic Colorectal Cancer
Study ID: NCT05425940
Brief Summary: This is a multicenter, randomized, open-label, controlled Phase 3 trial of XL092 + atezolizumab vs regorafenib in subjects with microsatellite stable/microsatellite instability low (MSS/MSI-low) metastatic colorectal cancer (mCRC) who have progressed during, after or are intolerant to standard-of-care (SOC) therapy.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Exelixis Clinical Site #65, Jonesboro, Alabama, United States
Exelixis Clinical Site #30, Phoenix, Arizona, United States
Exelixis Clinical Site #70, Tucson, Arizona, United States
Exelixis Clinical Site #9, Duarte, California, United States
Exelixis Clinical Site #55, La Jolla, California, United States
Exelixis Clinical Site #77, Los Angeles, California, United States
Exelixis Clinical Site #105, Orange, California, United States
Exelixis Clinical Site #80, Santa Monica, California, United States
Exelixis Clinical Site #5, Santa Rosa, California, United States
Exelixis Clinical Site #82, Sylmar, California, United States
Exelixis Clinical Site #58, Torrance, California, United States
Exelixis Clinical Site #81, Whittier, California, United States
Exelixis Clinical Site #125, New Haven, Connecticut, United States
Exelixis Clinical Site #16, Miami Beach, Florida, United States
Exelixis Clinical Site #60, Orlando, Florida, United States
Exelixis Clinical Site #4, Marietta, Georgia, United States
Exelixis Clinical Site #3, Joliet, Illinois, United States
Exelixis Clinical Site #102, Indianapolis, Indiana, United States
Exelixis Clinical Site #10, Westwood, Kansas, United States
Exelixis Clinical Site #47, Lexington, Kentucky, United States
Exelixis Clinical Site #7, New Orleans, Louisiana, United States
Exelixis Clinical Site #22, Saint Louis, Missouri, United States
Exelixis Clinical Site #8, Billings, Montana, United States
Exelixis Clinical Site #1, Omaha, Nebraska, United States
Exelixis Clinical Site #15, Albuquerque, New Mexico, United States
Exelixis Clinical Site #17, Bronx, New York, United States
Exelixis Clinical Site #11, New York, New York, United States
Exelixis Clinical Site #59, New York, New York, United States
Exelixis Clinical Site #74, Charlotte, North Carolina, United States
Exelixis Clinical Site #6, Cincinnati, Ohio, United States
Exelixis Clinical Site #12, Oklahoma City, Oklahoma, United States
Exelixis Clinical Site #75, Portland, Oregon, United States
Exelixis Clinical Site #106, Philadelphia, Pennsylvania, United States
Exelixis Clinical Site #18, Pittsburgh, Pennsylvania, United States
Exelixis Clinical Site #103, Pittsburgh, Pennsylvania, United States
Exelixis Clinical Site #24, Greenville, South Carolina, United States
Exelixis Clinical Site #56, Chattanooga, Tennessee, United States
Exelixis Clinical Site #76, Nashville, Tennessee, United States
Exelixis Clinical Site #133, Nashville, Tennessee, United States
Exelixis Clinical Site #450, Fairfax, Virginia, United States
Exelixis Clinical Site #14, Roanoke, Virginia, United States
Exelixis Clinical Site #13, Seattle, Washington, United States
Exelixis Clinical Site #32, Seattle, Washington, United States
Exelixis Clinical Site #89, Seattle, Washington, United States
Exelixis Clinical Site #2, Spokane, Washington, United States
Exelixis Clinical Site #83, Albury, , Australia
Exelixis Clinical Site #53, Bankstown, , Australia
Exelixis Clinical Site #117, Bedford Park, , Australia
Exelixis Clinical Site #97, Heidelberg, , Australia
Exelixis Clinical Site #19, Melbourne, , Australia
Exelixis Clinical Site #23, Melbourne, , Australia
Exelixis Clinical Site #27, Port Macquarie, , Australia
Exelixis Clinical Site #64, Woodville South, , Australia
Exelixis Clinical Site #43, Antwerp, , Belgium
Exelixis Clinical Site #51, Brussels, , Belgium
Exelixis Clinical Site #35, Namur, , Belgium
Exelixis Clinical Site #52, Besançon, , France
Exelixis Clinical Site #84, Dijon, , France
Exelixis Clinical Site #88, Herbault, , France
Exelixis Clinical Site #71, Lyon, , France
Exelixis Clinical Site #87, Marseille, , France
Exelixis Clinical Site #38, Paris, , France
Exelixis Clinical Site #93, Suresnes, , France
Exelixis Clinical Site #127, Hannover, Niedersach, Germany
Exelixis Clinical Site #109, Dresden, , Germany
Exelixis Clinical Site #113, Frankfurt am Main, , Germany
Exelixis Clinical Site #61, Hamburg, , Germany
Exelixis Clinical Site #63, Hamburg, , Germany
Exelixis Clinical Site #91, München, , Germany
Exelixis Clinical Site #25, Hong Kong, , Hong Kong
Exelixis Clinical Site #33, Hong Kong, , Hong Kong
Exelixis Clinical Site #128, Nyíregyháza, Szabolcs-Szatmar-Bereg County, Hungary
Exelixis Clinical Site #41, Budapest, , Hungary
Exelixis Clinical Site #129, Budapest, , Hungary
Exelixis Clinical Site #48, Debrecen, , Hungary
Exelixis Clinical Site #122, Győr, , Hungary
Exelixis Clinical Site #36, Goyang-si, , Korea, Republic of
Exelixis Clinical Site #29, Gyeonggi-do, , Korea, Republic of
Exelixis Clinical Site #28, Hwasun, , Korea, Republic of
Exelixis Clinical Site #37, Seongnam-si, , Korea, Republic of
Exelixis Clinical Site #34, Seoul, , Korea, Republic of
Exelixis Clinical Site #45, Seoul, , Korea, Republic of
Exelixis Clinical Site #66, Seoul, , Korea, Republic of
Exelixis Clinical Site #46, Seoul, , Korea, Republic of
Exelixis Clinical Site #54, Seoul, , Korea, Republic of
Exelixis Clinical Site #44, Seoul, , Korea, Republic of
Exelixis Clinical Site #40, Seoul, , Korea, Republic of
Exelixis Clinical Site #57, Auckland, , New Zealand
Exelixis Clinical Site #49, Dunedin, , New Zealand
Exelixis Clinical Site #69, Hamilton, , New Zealand
Exelixis Clinical Site #104, Wellington, , New Zealand
Exelixis Clinical Site #20, Bydgoszcz, , Poland
Exelixis Clinical Site #68, Opole, , Poland
Exelixis Clinical Site #26, Siedlce, , Poland
Exelixis Clinical Site #42, Tomaszów Mazowiecki, , Poland
Exelixis Clinical Site #31, Warszawa, , Poland
Exelixis Clinical Site #108, Almada, , Portugal
Exelixis Clinical Site #120, Coimbra, , Portugal
Exelixis Clinical Site #99, Guimarães, , Portugal
Exelixis Clinical Site #131, Lisboa, , Portugal
Exelixis Clinical Site #124, Lisboa, , Portugal
Exelixis Clinical Site #96, Lisboa, , Portugal
Exelixis Clinical Site #132, Singapore, , Singapore
Exelixis Clinical Site #100, Singapore, , Singapore
Exelixis Clinical Site #39, Singapore, , Singapore
Exelixis Clinical Site #98, Singapore, , Singapore
Exelixis Clinical Site #94, Singapore, , Singapore
Exelixis Clinical Site #78, Barcelona, , Spain
Exelixis Clinical Site #21, Barcelona, , Spain
Exelixis Clinical Site #86, Barcelona, , Spain
Exelixis Clinical Site #112, Barcelona, , Spain
Exelixis Clinical Site #95, Lleida, , Spain
Exelixis Clinical Site #116, Madrid, , Spain
Exelixis Clinical Site #72, Madrid, , Spain
Exelixis Clinical Site #67, Madrid, , Spain
Exelixis Clinical Site #79, Madrid, , Spain
Exelixis Clinical Site #90, Valencia, , Spain
Exelixis Clinical Site #121, Zaragoza, , Spain
Exelixis Clinical Site #119, Guishan, , Taiwan
Exelixis Clinical Site #85, Kaohsiung, , Taiwan
Exelixis Clinical Site #107, Kaohsiung, , Taiwan
Exelixis Clinical Site #118, Liuying, , Taiwan
Exelixis Clinical Site #73, Taichung, , Taiwan
Exelixis Clinical Site #101, Tainan, , Taiwan
Exelixis Clinical Site #62, Chiang Mai, , Thailand
Exelixis Clinical Site #92, Hat Yai, , Thailand
Exelixis Clinical Site #130, Bristol, England, United Kingdom
Exelixis Clinical Site #110, Birmingham, , United Kingdom
Exelixis Clinical Site #111, Edinburgh, , United Kingdom
Exelixis Clinical Site #123, London, , United Kingdom
Exelixis Clinical Site #114, London, , United Kingdom
Exelixis Clinical Site #115, Romford, , United Kingdom
Exelixis Clinical Site #126, Sutton, , United Kingdom