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Brief Title: A Study of BBI608 in Adult Patients With Advanced Colorectal Cancer
Official Title: A Phase II Clinical Study of BBI608 in Adult Patients With Advanced Colorectal Cancer
Study ID: NCT01776307
Brief Summary: This is an open label, multi-center, Phase 2 study of BBI608 in combination with cetuximab, panitumumab or capecitabine in patients with advanced colorectal cancer.
Detailed Description: This is an open label, multi-center, Phase 2 study of BBI608 administered in combination with either cetuximab, or panitumumab, or capecitabine. A cycle will consist of daily and continuous oral administration of BBI608 for four weeks in combination with either cetuximab, or panitumumab, or capecitabine.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Mayo Clinic, Scottsdale, Arizona, United States
USOR - Rocky Mountain Cancer Center, Denver, Colorado, United States
Mayo Clinic, Jacksonville, Florida, United States
USOR - Minnesota Oncology Hematology, Minneapolis, Minnesota, United States
Mayo Clinic, Rochester, Minnesota, United States
The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States
USOR - Northwest Cancer Specialists, Portland, Oregon, United States
Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Institute for Translational Oncology Research, Greenville Hospital System, Greenville, South Carolina, United States
USOR - Texas Oncology Dallas, Dallas, Texas, United States
US Oncology Research, The Woodlands, Texas, United States
USOR - Texas Oncology Tyler, Tyler, Texas, United States
USOR - Virginia Cancer Specialists, Fairfax, Virginia, United States
Name: William J. Edenfield, MD
Affiliation: Institute for Translational Oncology Research, Greenville Hospital System
Role: PRINCIPAL_INVESTIGATOR