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Spots Global Cancer Trial Database for S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer

Official Title: Randomized Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer

Study ID: NCT02164916

Study Description

Brief Summary: This randomized phase II trial studies how well irinotecan hydrochloride and cetuximab with or without vemurafenib works in treating patients with colorectal cancer that has spread to nearby tissue or lymph nodes, that has spread to other places in the body, or cannot be removed by surgery. Irinotecan hydrochloride and vemurafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as cetuximab, may block the ability of tumor cells to grow and spread. It is not yet known whether irinotecan hydrochloride and cetuximab are more effective with or without vemurafenib in treating colorectal cancer.

Detailed Description: PRIMARY OBJECTIVES: I. To evaluate the progression-free survival (PFS) of v-raf murine sarcoma viral oncogene homolog B (BRAF) mutant metastatic colorectal cancer patients treated with irinotecan (irinotecan hydrochloride), cetuximab, and vemurafenib, compared to a control arm of irinotecan and cetuximab. SECONDARY OBJECTIVES: I. To evaluate the frequency and severity of toxicity associated with each of the treatment arms in this patient population. TERTIARY OBJECTIVES: I. To evaluate overall survival (OS) in treatment Arms 1 and 2. II. To evaluate the overall response rate (ORR), including confirmed and unconfirmed, complete and partial response, in treatment Arms 1 and 2 in the subset of patients with measurable disease. III. To estimate rates of OS, ORR, and PFS in patients who register to Arm 3 after disease progression on Arm 1. IV. To evaluate low-frequency Kirsten rat sarcoma viral oncogene homolog (KRAS) or neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) mutations as detected by high-depth sequencing as predictive biomarkers of efficacy. V. To evaluate phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (PIK3CA) pathway activation through PIK3CA mutations or phosphatase and tensin homolog (PTEN) protein loss as a predictive biomarker of innate resistance to this regimen. VI. To evaluate gene expression signatures from screened patients with v-raf murine sarcoma viral oncogene homolog B wild type (BRAFWT) and BRAFV600E tumors. VII. To provide validation of BRAF immunohistochemistry (IHC) using complementary sequencing methodology from screened patients with BRAFWT and BRAFV600E tumors. VIII. To confirm the estimated sensitivity of detectable BRAF V600E circulating cell-free deoxyribonucleic acid (DNA) as a non-invasive biomarker for BRAF V600E mutation as detected by IHC in the primary tumor. IX. To correlate radiographic tumor response with change in quantification of BRAFV600E alleles in circulating cell-free DNA. X. To monitor for known mechanism of acquired resistance to epidermal growth factor receptor (EGFR) inhibition in circulating cell-free DNA (KRAS, NRAS mutations). OUTLINE: Patients are randomized to 1 of 2 treatment arms. ARM I: Patients receive cetuximab intravenously (IV) and irinotecan hydrochloride IV on days 1 and 14. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients with disease progression may cross over to Arm II. ARM II: Patients receive cetuximab and irinotecan hydrochloride as in Arm I and vemurafenib orally (PO) twice daily (BID) on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. After completion of study treatment, patients are followed up every 2-6 months for 3 years.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Anchorage Radiation Therapy Center, Anchorage, Alaska, United States

Alaska Breast Care and Surgery LLC, Anchorage, Alaska, United States

Alaska Oncology and Hematology LLC, Anchorage, Alaska, United States

Alaska Regional Hospital, Anchorage, Alaska, United States

Alaska Women's Cancer Care, Anchorage, Alaska, United States

Anchorage Oncology Centre, Anchorage, Alaska, United States

Katmai Oncology Group, Anchorage, Alaska, United States

Providence Alaska Medical Center, Anchorage, Alaska, United States

Fairbanks Memorial Hospital, Fairbanks, Alaska, United States

University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona, United States

University of Arizona Cancer Center-North Campus, Tucson, Arizona, United States

The University of Arizona Medical Center-University Campus, Tucson, Arizona, United States

Mercy Cancer Center-Hot Springs, Hot Springs, Arkansas, United States

Fowler Family Center for Cancer Care, Jonesboro, Arkansas, United States

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

Veteran's Administration Medical Center, Little Rock, Arkansas, United States

Kaiser Permanente-Anaheim, Anaheim, California, United States

Kaiser Permanente-Deer Valley Medical Center, Antioch, California, United States

Sutter Auburn Faith Hospital, Auburn, California, United States

Sutter Cancer Centers Radiation Oncology Services-Auburn, Auburn, California, United States

Kaiser Permanente-Baldwin Park, Baldwin Park, California, United States

Kaiser Permanente-Bellflower, Bellflower, California, United States

Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California, United States

Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California, United States

Mills - Peninsula Hospitals, Burlingame, California, United States

Sutter Cancer Centers Radiation Oncology Services-Cameron Park, Cameron Park, California, United States

Eden Hospital Medical Center, Castro Valley, California, United States

Sutter Davis Hospital, Davis, California, United States

City of Hope Comprehensive Cancer Center, Duarte, California, United States

Epic Care-Dublin, Dublin, California, United States

Bay Area Breast Surgeons Inc, Emeryville, California, United States

Epic Care Partners in Cancer Care, Emeryville, California, United States

Kaiser Permanente Hospital, Fontana, California, United States

Kaiser Permanente-Fremont, Fremont, California, United States

Kaiser Permanente, Fresno, California, United States

Marin Cancer Care Inc, Greenbrae, California, United States

Marin General Hospital, Greenbrae, California, United States

Kaiser Permanente - Harbor City, Harbor City, California, United States

Kaiser Permanente-Irvine, Irvine, California, United States

Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States

Los Angeles County-USC Medical Center, Los Angeles, California, United States

USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States

Kaiser Permanente-Cadillac, Los Angeles, California, United States

Contra Costa Regional Medical Center, Martinez, California, United States

Fremont - Rideout Cancer Center, Marysville, California, United States

Memorial Medical Center, Modesto, California, United States

Kaiser Permanente-Modesto, Modesto, California, United States

Palo Alto Medical Foundation-Camino Division, Mountain View, California, United States

Palo Alto Medical Foundation-Gynecologic Oncology, Mountain View, California, United States

Sutter Cancer Research Consortium, Novato, California, United States

Alta Bates Summit Medical Center - Summit Campus, Oakland, California, United States

Bay Area Tumor Institute, Oakland, California, United States

Hematology and Oncology Associates-Oakland, Oakland, California, United States

Kaiser Permanente Oakland-Broadway, Oakland, California, United States

Kaiser Permanente-Oakland, Oakland, California, United States

UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California, United States

Palo Alto Medical Foundation Health Care, Palo Alto, California, United States

Kaiser Permanente - Panorama City, Panorama City, California, United States

Keck Medical Center of USC Pasadena, Pasadena, California, United States

PCR Oncology, Pismo Beach, California, United States

Kaiser Permanente-Rancho Cordova Cancer Center, Rancho Cordova, California, United States

Kaiser Permanente-Redwood City, Redwood City, California, United States

Kaiser Permanente-Richmond, Richmond, California, United States

Kaiser Permanente-Riverside, Riverside, California, United States

Rohnert Park Cancer Center, Rohnert Park, California, United States

Kaiser Permanente-Roseville, Roseville, California, United States

Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California, United States

Sutter Roseville Medical Center, Roseville, California, United States

The Permanente Medical Group-Roseville Radiation Oncology, Roseville, California, United States

Sutter General Hospital, Sacramento, California, United States

University of California Davis Comprehensive Cancer Center, Sacramento, California, United States

Kaiser Permanente-South Sacramento, Sacramento, California, United States

South Sacramento Cancer Center, Sacramento, California, United States

Kaiser Permanente - Sacramento, Sacramento, California, United States

Salinas Valley Memorial, Salinas, California, United States

Kaiser Permanente-San Diego Mission, San Diego, California, United States

Kaiser Permanente-San Diego Zion, San Diego, California, United States

California Pacific Medical Center-Pacific Campus, San Francisco, California, United States

Kaiser Permanente-San Francisco, San Francisco, California, United States

UCSF Medical Center-Mount Zion, San Francisco, California, United States

UCSF Medical Center-Mission Bay, San Francisco, California, United States

Kaiser Permanente-Santa Teresa-San Jose, San Jose, California, United States

Kaiser Permanente San Leandro, San Leandro, California, United States

Kaiser Permanente-San Marcos, San Marcos, California, United States

Kaiser Permanente-San Rafael, San Rafael, California, United States

Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California, United States

Palo Alto Medical Foundation-Santa Cruz, Santa Cruz, California, United States

Kaiser Permanente-Santa Rosa, Santa Rosa, California, United States

Sutter Pacific Medical Foundation, Santa Rosa, California, United States

Kaiser Permanente Cancer Treatment Center, South San Francisco, California, United States

Kaiser Permanente-South San Francisco, South San Francisco, California, United States

Kaiser Permanente-Stockton, Stockton, California, United States

Palo Alto Medical Foundation-Sunnyvale, Sunnyvale, California, United States

Gene Upshaw Memorial Tahoe Forest Cancer Center, Truckee, California, United States

Sutter Cancer Centers Radiation Oncology Services-Vacaville, Vacaville, California, United States

Kaiser Permanente Medical Center-Vacaville, Vacaville, California, United States

Kaiser Permanente-Vallejo, Vallejo, California, United States

Sutter Solano Medical Center/Cancer Center, Vallejo, California, United States

Kaiser Permanente-Walnut Creek, Walnut Creek, California, United States

Kaiser Permanente, Woodland Hills, California, United States

Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado, United States

The Medical Center of Aurora, Aurora, Colorado, United States

University of Colorado Cancer Center - Anschutz Cancer Pavilion, Aurora, Colorado, United States

Boulder Community Hospital, Boulder, Colorado, United States

Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado, United States

Penrose-Saint Francis Healthcare, Colorado Springs, Colorado, United States

Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado, United States

Memorial Hospital Colorado Springs, Colorado Springs, Colorado, United States

Denver Health Medical Center, Denver, Colorado, United States

Porter Adventist Hospital, Denver, Colorado, United States

Colorado Blood Cancer Institute, Denver, Colorado, United States

Presbyterian - Saint Lukes Medical Center - Health One, Denver, Colorado, United States

Rocky Mountain Cancer Centers-Midtown, Denver, Colorado, United States

SCL Health Saint Joseph Hospital, Denver, Colorado, United States

Rocky Mountain Cancer Centers-Rose, Denver, Colorado, United States

Rose Medical Center, Denver, Colorado, United States

Colorado Cancer Research Program NCORP, Denver, Colorado, United States

Mercy Medical Center, Durango, Colorado, United States

Southwest Oncology PC, Durango, Colorado, United States

Comprehensive Cancer Care and Research Institute of Colorado LLC, Englewood, Colorado, United States

Swedish Medical Center, Englewood, Colorado, United States

Poudre Valley Hospital, Fort Collins, Colorado, United States

Mountain Blue Cancer Care Center, Golden, Colorado, United States

National Jewish Health-Western Hematology Oncology, Golden, Colorado, United States

North Colorado Medical Center, Greeley, Colorado, United States

Rocky Mountain Cancer Centers-Greenwood Village, Greenwood Village, Colorado, United States

Rocky Mountain Cancer Centers-Lakewood, Lakewood, Colorado, United States

Saint Anthony Hospital, Lakewood, Colorado, United States

Rocky Mountain Cancer Centers-Littleton, Littleton, Colorado, United States

Littleton Adventist Hospital, Littleton, Colorado, United States

Rocky Mountain Cancer Centers-Sky Ridge, Lone Tree, Colorado, United States

Sky Ridge Medical Center, Lone Tree, Colorado, United States

Longmont United Hospital, Longmont, Colorado, United States

Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado, United States

McKee Medical Center, Loveland, Colorado, United States

Parker Adventist Hospital, Parker, Colorado, United States

Rocky Mountain Cancer Centers-Parker, Parker, Colorado, United States

Saint Mary Corwin Medical Center, Pueblo, Colorado, United States

Rocky Mountain Cancer Centers - Pueblo, Pueblo, Colorado, United States

Rocky Mountain Cancer Centers-Thornton, Thornton, Colorado, United States

SCL Health Lutheran Medical Center, Wheat Ridge, Colorado, United States

Smilow Cancer Hospital-Derby Care Center, Derby, Connecticut, United States

Smilow Cancer Hospital Care Center-Fairfield, Fairfield, Connecticut, United States

Greenwich Hospital, Greenwich, Connecticut, United States

Medical Oncology and Hematology Group PC-Guilford, Guilford, Connecticut, United States

Smilow Cancer Hospital Care Center at Saint Francis, Hartford, Connecticut, United States

Middlesex Hospital, Middletown, Connecticut, United States

Yale University, New Haven, Connecticut, United States

Yale-New Haven Hospital North Haven Medical Center, North Haven, Connecticut, United States

Eastern Connecticut Hematology and Oncology Associates, Norwich, Connecticut, United States

Smilow Cancer Hospital-Orange Care Center, Orange, Connecticut, United States

Charlotte Hungerford Hospital Center for Cancer Care, Torrington, Connecticut, United States

Smilow Cancer Hospital Care Center-Trumbull, Trumbull, Connecticut, United States

Smilow Cancer Hospital-Waterbury Care Center, Waterbury, Connecticut, United States

Beebe Medical Center, Lewes, Delaware, United States

Christiana Gynecologic Oncology LLC, Newark, Delaware, United States

Delaware Clinical and Laboratory Physicians PA, Newark, Delaware, United States

Helen F Graham Cancer Center, Newark, Delaware, United States

Medical Oncology Hematology Consultants PA, Newark, Delaware, United States

Regional Hematology and Oncology PA, Newark, Delaware, United States

Christiana Care Health System-Christiana Hospital, Newark, Delaware, United States

Beebe Health Campus, Rehoboth Beach, Delaware, United States

Nanticoke Memorial Hospital, Seaford, Delaware, United States

Christiana Care Health System-Wilmington Hospital, Wilmington, Delaware, United States

Florida Hospital Cancer Institute Altamonte, Altamonte Springs, Florida, United States

University of Florida, Gainesville, Florida, United States

Florida Hospital Kissimmee, Kissimmee, Florida, United States

Mount Sinai Medical Center, Miami Beach, Florida, United States

Florida Hospital Orlando, Orlando, Florida, United States

Florida Urology Associates-Orlando, Orlando, Florida, United States

UF Cancer Center at Orlando Health, Orlando, Florida, United States

Florida Hospital East Orlando, Orlando, Florida, United States

Florida Hospital Cancer Institute Winter Park, Winter Park, Florida, United States

Northside Hospital, Atlanta, Georgia, United States

John B Amos Cancer Center, Columbus, Georgia, United States

Memorial University Medical Center, Savannah, Georgia, United States

Summit Cancer Care-Memorial, Savannah, Georgia, United States

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah, Georgia, United States

Low Country Cancer Care Associates PC, Savannah, Georgia, United States

Hawaii Oncology Inc-Pali Momi, 'Aiea, Hawaii, United States

Pali Momi Medical Center, 'Aiea, Hawaii, United States

The Cancer Center of Hawaii-Leeward, 'Ewa Beach, Hawaii, United States

Hawaii Cancer Care Inc-POB II, Honolulu, Hawaii, United States

Queen's Medical Center, Honolulu, Hawaii, United States

Straub Clinic and Hospital, Honolulu, Hawaii, United States

University of Hawaii Cancer Center, Honolulu, Hawaii, United States

Hawaii Cancer Care Inc-Liliha, Honolulu, Hawaii, United States

Hawaii Oncology Inc-Kuakini, Honolulu, Hawaii, United States

Kuakini Medical Center, Honolulu, Hawaii, United States

The Cancer Center of Hawaii-Liliha, Honolulu, Hawaii, United States

Kaiser Permanente Moanalua Medical Center, Honolulu, Hawaii, United States

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii, United States

Wilcox Memorial Hospital and Kauai Medical Clinic, Lihue, Hawaii, United States

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho, United States

Saint Luke's Mountain States Tumor Institute, Boise, Idaho, United States

Saint Luke's Mountain States Tumor Institute - Fruitland, Fruitland, Idaho, United States

Saint Luke's Mountain States Tumor Institute - Meridian, Meridian, Idaho, United States

Saint Luke's Mountain States Tumor Institute - Nampa, Nampa, Idaho, United States

Saint Luke's Mountain States Tumor Institute-Twin Falls, Twin Falls, Idaho, United States

Rush - Copley Medical Center, Aurora, Illinois, United States

Saint Joseph Medical Center, Bloomington, Illinois, United States

Illinois CancerCare-Bloomington, Bloomington, Illinois, United States

Illinois CancerCare-Canton, Canton, Illinois, United States

Memorial Hospital of Carbondale, Carbondale, Illinois, United States

Illinois CancerCare-Carthage, Carthage, Illinois, United States

Centralia Oncology Clinic, Centralia, Illinois, United States

Northwestern University, Chicago, Illinois, United States

John H Stroger Jr Hospital of Cook County, Chicago, Illinois, United States

University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States

Carle on Vermilion, Danville, Illinois, United States

Cancer Care Center of Decatur, Decatur, Illinois, United States

Decatur Memorial Hospital, Decatur, Illinois, United States

Carle Physician Group-Effingham, Effingham, Illinois, United States

Crossroads Cancer Center, Effingham, Illinois, United States

Illinois CancerCare-Eureka, Eureka, Illinois, United States

NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois, United States

Illinois CancerCare-Galesburg, Galesburg, Illinois, United States

Western Illinois Cancer Treatment Center, Galesburg, Illinois, United States

NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois, United States

NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois, United States

Joliet Oncology-Hematology Associates Limited, Joliet, Illinois, United States

Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois, United States

Illinois CancerCare-Macomb, Macomb, Illinois, United States

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois, United States

Loyola University Medical Center, Maywood, Illinois, United States

Good Samaritan Regional Health Center, Mount Vernon, Illinois, United States

Edward Hospital/Cancer Center, Naperville, Illinois, United States

UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois, United States

Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois, United States

Radiation Oncology of Northern Illinois, Ottawa, Illinois, United States

Illinois CancerCare-Pekin, Pekin, Illinois, United States

OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center, Pekin, Illinois, United States

Methodist Medical Center of Illinois, Peoria, Illinois, United States

Illinois CancerCare-Peoria, Peoria, Illinois, United States

OSF Saint Francis Radiation Oncology at Peoria Cancer Center, Peoria, Illinois, United States

OSF Saint Francis Medical Center, Peoria, Illinois, United States

Illinois CancerCare-Peru, Peru, Illinois, United States

Valley Radiation Oncology, Peru, Illinois, United States

Edward Hospital/Cancer Center?Plainfield, Plainfield, Illinois, United States

Illinois CancerCare-Princeton, Princeton, Illinois, United States

North Shore Medical Center, Skokie, Illinois, United States

Central Illinois Hematology Oncology Center, Springfield, Illinois, United States

Southern Illinois University School of Medicine, Springfield, Illinois, United States

Springfield Clinic, Springfield, Illinois, United States

Memorial Medical Center, Springfield, Illinois, United States

Cancer Care Specialists of Illinois-Swansea, Swansea, Illinois, United States

Carle Cancer Center, Urbana, Illinois, United States

The Carle Foundation Hospital, Urbana, Illinois, United States

Rush-Copley Healthcare Center, Yorkville, Illinois, United States

Franciscan Saint Anthony Health-Michigan City, Michigan City, Indiana, United States

Woodland Cancer Care Center, Michigan City, Indiana, United States

Memorial Regional Cancer Center Day Road, Mishawaka, Indiana, United States

Reid Health, Richmond, Indiana, United States

Memorial Hospital of South Bend, South Bend, Indiana, United States

Northern Indiana Cancer Research Consortium, South Bend, Indiana, United States

Porter Memorial Hospital, Valparaiso, Indiana, United States

Mary Greeley Medical Center, Ames, Iowa, United States

McFarland Clinic PC-William R Bliss Cancer Center, Ames, Iowa, United States

McFarland Clinic PC-Boone, Boone, Iowa, United States

Medical Oncology and Hematology Associates-West Des Moines, Clive, Iowa, United States

Mercy Cancer Center-West Lakes, Clive, Iowa, United States

Alegent Health Mercy Hospital, Council Bluffs, Iowa, United States

Greater Regional Medical Center, Creston, Iowa, United States

Medical Oncology and Hematology Associates-Laurel, Des Moines, Iowa, United States

Mercy Medical Center - Des Moines, Des Moines, Iowa, United States

McFarland Clinic PC-Trinity Cancer Center, Fort Dodge, Iowa, United States

McFarland Clinic PC-Jefferson, Jefferson, Iowa, United States

McFarland Clinic PC-Marshalltown, Marshalltown, Iowa, United States

Mercy Medical Center - North Iowa, Mason City, Iowa, United States

Story County Medical Center-South Campus, Nevada, Iowa, United States

Siouxland Regional Cancer Center, Sioux City, Iowa, United States

Mercy Medical Center-West Lakes, West Des Moines, Iowa, United States

Cancer Center of Kansas - Chanute, Chanute, Kansas, United States

Cancer Center of Kansas - Dodge City, Dodge City, Kansas, United States

Cancer Center of Kansas - El Dorado, El Dorado, Kansas, United States

Newman Regional Health, Emporia, Kansas, United States

Cancer Center of Kansas - Fort Scott, Fort Scott, Kansas, United States

Saint Catherine Hospital, Garden City, Kansas, United States

Saint Rose Ambulatory and Surgery Center, Great Bend, Kansas, United States

Hays Medical Center, Hays, Kansas, United States

Cancer Center of Kansas-Independence, Independence, Kansas, United States

University of Kansas Cancer Center-West, Kansas City, Kansas, United States

University of Kansas Cancer Center, Kansas City, Kansas, United States

Cancer Center of Kansas-Kingman, Kingman, Kansas, United States

Lawrence Memorial Hospital, Lawrence, Kansas, United States

Cancer Center of Kansas-Liberal, Liberal, Kansas, United States

Cancer Center of Kansas - Newton, Newton, Kansas, United States

Olathe Medical Center, Olathe, Kansas, United States

University of Kansas Cancer Center-Overland Park, Overland Park, Kansas, United States

Cancer Center of Kansas - Parsons, Parsons, Kansas, United States

Via Christi Hospital-Pittsburg, Pittsburg, Kansas, United States

Cancer Center of Kansas - Pratt, Pratt, Kansas, United States

Cancer Center of Kansas - Salina, Salina, Kansas, United States

Salina Regional Health Center, Salina, Kansas, United States

Saint Francis Hospital and Medical Center - Topeka, Topeka, Kansas, United States

Cancer Center of Kansas - Wellington, Wellington, Kansas, United States

Associates In Womens Health, Wichita, Kansas, United States

Cancer Center of Kansas-Wichita Medical Arts Tower, Wichita, Kansas, United States

Cancer Center of Kansas - Wichita, Wichita, Kansas, United States

Via Christi Regional Medical Center, Wichita, Kansas, United States

Wichita NCI Community Oncology Research Program, Wichita, Kansas, United States

Cancer Center of Kansas - Winfield, Winfield, Kansas, United States

Flaget Memorial Hospital, Bardstown, Kentucky, United States

Commonwealth Cancer Center-Corbin, Corbin, Kentucky, United States

Oncology Hematology Care Inc-Crestview, Crestview Hills, Kentucky, United States

Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky, United States

Saint Joseph Hospital East, Lexington, Kentucky, United States

Jewish Hospital, Louisville, Kentucky, United States

Saints Mary and Elizabeth Hospital, Louisville, Kentucky, United States

Jewish Hospital Medical Center Northeast, Louisville, Kentucky, United States

Jewish Hospital Medical Center South, Shepherdsville, Kentucky, United States

Christus Saint Frances Cabrini Hospital, Alexandria, Louisiana, United States

LSU Health Baton Rouge-North Clinic, Baton Rouge, Louisiana, United States

Louisiana Hematology Oncology Associates LLC, Baton Rouge, Louisiana, United States

Medical Oncology LLC, Baton Rouge, Louisiana, United States

Mary Bird Cancer Center/Saint Tammany Parish, Covington, Louisiana, United States

Mary Bird Perkins Cancer Center/Terrebonne General Medical Center, Houma, Louisiana, United States

Ochsner Medical Center Jefferson, New Orleans, Louisiana, United States

Harold Alfond Center for Cancer Care, Augusta, Maine, United States

Eastern Maine Medical Center, Bangor, Maine, United States

Lafayette Family Cancer Center-EMMC, Brewer, Maine, United States

Sinai Hospital of Baltimore, Baltimore, Maryland, United States

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland, United States

Union Hospital of Cecil County, Elkton, Maryland, United States

Northwest Hospital Center, Randallstown, Maryland, United States

Peninsula Regional Medical Center, Salisbury, Maryland, United States

Beverly Hospital, Beverly, Massachusetts, United States

Lahey Hospital and Medical Center, Burlington, Massachusetts, United States

Addison Gilbert Hospital, Gloucester, Massachusetts, United States

Baystate Medical Center, Springfield, Massachusetts, United States

Hickman Cancer Center, Adrian, Michigan, United States

Saint Joseph Mercy Hospital, Ann Arbor, Michigan, United States

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

Bronson Battle Creek, Battle Creek, Michigan, United States

McLaren-Bay Region, Bay City, Michigan, United States

Henry Ford Cancer Institute¿Downriver, Brownstown, Michigan, United States

Great Lakes Cancer Institute, Clarkston, Michigan, United States

Henry Ford Macomb Hospital-Clinton Township, Clinton Township, Michigan, United States

Beaumont Hospital-Dearborn, Dearborn, Michigan, United States

Henry Ford Medical Center-Fairlane, Dearborn, Michigan, United States

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan, United States

Henry Ford Hospital, Detroit, Michigan, United States

Saint John Hospital and Medical Center, Detroit, Michigan, United States

Green Bay Oncology - Escanaba, Escanaba, Michigan, United States

Weisberg Cancer Treatment Center, Farmington Hills, Michigan, United States

Hurley Medical Center, Flint, Michigan, United States

Genesys Hurley Cancer Institute, Flint, Michigan, United States

Singh and Arora Hematology Oncology PC, Flint, Michigan, United States

Mercy Health Saint Mary's, Grand Rapids, Michigan, United States

Spectrum Health at Butterworth Campus, Grand Rapids, Michigan, United States

Allegiance Health, Jackson, Michigan, United States

Borgess Medical Center, Kalamazoo, Michigan, United States

Bronson Methodist Hospital, Kalamazoo, Michigan, United States

West Michigan Cancer Center, Kalamazoo, Michigan, United States

McLaren-Greater Lansing, Lansing, Michigan, United States

Sparrow Hospital, Lansing, Michigan, United States

McLaren Cancer Institute-Lapeer Region, Lapeer, Michigan, United States

Saint Mary Mercy Hospital, Livonia, Michigan, United States

Monroe Cancer Center, Monroe, Michigan, United States

Toledo Clinic Cancer Centers-Monroe, Monroe, Michigan, United States

McLaren Cancer Institute-Macomb, Mount Clemens, Michigan, United States

McLaren Cancer Institute-Central Michigan, Mount Pleasant, Michigan, United States

Mercy Health Mercy Campus, Muskegon, Michigan, United States

Lakeland Community Hospital, Niles, Michigan, United States

Assarian Cancer Center, Novi, Michigan, United States

Henry Ford Medical Center-Columbus, Novi, Michigan, United States

McLaren Cancer Institute-Northern Michigan, Petoskey, Michigan, United States

Saint Joseph Mercy Oakland, Pontiac, Michigan, United States

Lake Huron Medical Center, Port Huron, Michigan, United States

Spectrum Health Reed City Hospital, Reed City, Michigan, United States

Saint Mary's of Michigan, Saginaw, Michigan, United States

Lakeland Hospital, Saint Joseph, Michigan, United States

Marie Yeager Cancer Center, Saint Joseph, Michigan, United States

Providence Hospital-Southfield Cancer Center, Southfield, Michigan, United States

Munson Medical Center, Traverse City, Michigan, United States

Saint John Macomb-Oakland Hospital, Warren, Michigan, United States

Henry Ford West Bloomfield Hospital, West Bloomfield, Michigan, United States

Sanford Clinic North-Bemidgi, Bemidji, Minnesota, United States

Essentia Health Saint Joseph's Medical Center, Brainerd, Minnesota, United States

Fairview Ridges Hospital, Burnsville, Minnesota, United States

Mercy Hospital, Coon Rapids, Minnesota, United States

Essentia Health Cancer Center, Duluth, Minnesota, United States

Essentia Health Saint Mary's Medical Center, Duluth, Minnesota, United States

Miller-Dwan Hospital, Duluth, Minnesota, United States

Saint Luke's Hospital of Duluth, Duluth, Minnesota, United States

Fairview-Southdale Hospital, Edina, Minnesota, United States

Lake Region Healthcare Corporation-Cancer Care, Fergus Falls, Minnesota, United States

Unity Hospital, Fridley, Minnesota, United States

Hutchinson Area Health Care, Hutchinson, Minnesota, United States

Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota, United States

Saint John's Hospital - Healtheast, Maplewood, Minnesota, United States

Abbott-Northwestern Hospital, Minneapolis, Minnesota, United States

Hennepin County Medical Center, Minneapolis, Minnesota, United States

Health Partners Inc, Minneapolis, Minnesota, United States

New Ulm Medical Center, New Ulm, Minnesota, United States

North Memorial Medical Health Center, Robbinsdale, Minnesota, United States

Mayo Clinic, Rochester, Minnesota, United States

Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud, Minnesota, United States

Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota, United States

Regions Hospital, Saint Paul, Minnesota, United States

United Hospital, Saint Paul, Minnesota, United States

Saint Francis Regional Medical Center, Shakopee, Minnesota, United States

Lakeview Hospital, Stillwater, Minnesota, United States

Ridgeview Medical Center, Waconia, Minnesota, United States

Rice Memorial Hospital, Willmar, Minnesota, United States

Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota, United States

Hattiesburg Clinic - Hematology/Oncology Clinic, Hattiesburg, Mississippi, United States

Forrest General Hospital / Cancer Center, Hattiesburg, Mississippi, United States

University of Mississippi Medical Center, Jackson, Mississippi, United States

Singing River Hospital, Pascagoula, Mississippi, United States

Central Care Cancer Center-Carrie J Babb Cancer Center, Bolivar, Missouri, United States

Parkland Health Center-Bonne Terre, Bonne Terre, Missouri, United States

CoxHealth Cancer Center, Branson, Missouri, United States

Saint Francis Medical Center, Cape Girardeau, Missouri, United States

Southeast Cancer Center, Cape Girardeau, Missouri, United States

Saint Luke's Hospital, Chesterfield, Missouri, United States

Barnes-Jewish West County Hospital, Creve Coeur, Missouri, United States

Capital Region Medical Center-Goldschmidt Cancer Center, Jefferson City, Missouri, United States

Freeman Health System, Joplin, Missouri, United States

Mercy Hospital-Joplin, Joplin, Missouri, United States

Truman Medical Center, Kansas City, Missouri, United States

The University of Kansas Cancer Center-South, Kansas City, Missouri, United States

The University of Kansas Cancer Center-North, Kansas City, Missouri, United States

The University of Kansas Cancer Center-Lee's Summit, Lee's Summit, Missouri, United States

Delbert Day Cancer Institute at PCRMC, Rolla, Missouri, United States

Saint John's Clinic-Rolla-Cancer and Hematology, Rolla, Missouri, United States

Saint Louis Cancer and Breast Institute-South City, Saint Louis, Missouri, United States

Washington University School of Medicine, Saint Louis, Missouri, United States

Missouri Baptist Medical Center, Saint Louis, Missouri, United States

Mercy Hospital Saint Louis, Saint Louis, Missouri, United States

Siteman Cancer Center - Saint Peters, Saint Peters, Missouri, United States

Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri, United States

Mercy Hospital Springfield, Springfield, Missouri, United States

CoxHealth South Hospital, Springfield, Missouri, United States

Missouri Baptist Sullivan Hospital, Sullivan, Missouri, United States

Missouri Baptist Outpatient Center-Sunset Hills, Sunset Hills, Missouri, United States

CHI Health Saint Francis, Grand Island, Nebraska, United States

Heartland Hematology and Oncology, Kearney, Nebraska, United States

CHI Health Good Samaritan, Kearney, Nebraska, United States

Nebraska Hematology and Oncology, Lincoln, Nebraska, United States

Nebraska Cancer Research Center, Lincoln, Nebraska, United States

Saint Elizabeth Regional Medical Center, Lincoln, Nebraska, United States

Southeast Nebraska Cancer Center, Lincoln, Nebraska, United States

Faith Regional Medical Offices West, Norfolk, Nebraska, United States

Great Plains Regional Medical Center, North Platte, Nebraska, United States

Missouri Valley Cancer Consortium, Omaha, Nebraska, United States

Alegent Health Immanuel Medical Center, Omaha, Nebraska, United States

Hemotology and Oncology Consultants PC, Omaha, Nebraska, United States

Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska, United States

Oncology Hematology West, Omaha, Nebraska, United States

Alegent Health Lakeside Hospital, Omaha, Nebraska, United States

Oncology Hematology West PC, Omaha, Nebraska, United States

Creighton University Medical Center, Omaha, Nebraska, United States

Midlands Community Hospital, Papillion, Nebraska, United States

Regional West Medical Center, Scottsbluff, Nebraska, United States

Cancer and Blood Specialists-Henderson, Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada - Henderson, Henderson, Nevada, United States

Las Vegas Cancer Center-Henderson, Henderson, Nevada, United States

21st Century Oncology - Henderson, Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada-Southeast Henderson, Henderson, Nevada, United States

Cancer and Blood Specialists-Shadow, Las Vegas, Nevada, United States

Radiation Oncology Centers of Nevada Central, Las Vegas, Nevada, United States

21st Century Oncology, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-San Martin, Las Vegas, Nevada, United States

Radiation Oncology Centers of Nevada Southeast, Las Vegas, Nevada, United States

Cancer Therapy and Integrative Medicine, Las Vegas, Nevada, United States

Cancer and Blood Specialists-Tenaya, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Northwest, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Tenaya, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada-Summerlin, Las Vegas, Nevada, United States

Summerlin Hospital Medical Center, Las Vegas, Nevada, United States

Las Vegas Cancer Center-Medical Center, Las Vegas, Nevada, United States

21st Century Oncology - Fort Apache, Las Vegas, Nevada, United States

Cancer and Blood Specialists-Fort Apache, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central Valley, Las Vegas, Nevada, United States

21st Century Oncology - Vegas Tenaya, Las Vegas, Nevada, United States

Saint Mary's Regional Medical Center, Reno, Nevada, United States

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States

Norris Cotton Cancer Center-Manchester, Manchester, New Hampshire, United States

Norris Cotton Cancer Center-Nashua, Nashua, New Hampshire, United States

Englewood Hospital and Medical Center, Englewood, New Jersey, United States

Virtua Memorial, Mount Holly, New Jersey, United States

Newark Beth Israel Medical Center, Newark, New Jersey, United States

The Valley Hospital-Luckow Pavilion, Paramus, New Jersey, United States

Valley Hospital, Ridgewood, New Jersey, United States

Sparta Cancer Treatment Center, Sparta, New Jersey, United States

Inspira Medical Center Vineland, Vineland, New Jersey, United States

Virtua Voorhees, Voorhees, New Jersey, United States

Valley Health System-Hematology/Oncology, Westwood, New Jersey, United States

Inspira Medical Center Woodbury, Woodbury, New Jersey, United States

University of New Mexico Cancer Center, Albuquerque, New Mexico, United States

Memorial Medical Center - Las Cruces, Las Cruces, New Mexico, United States

Montefiore Medical Center-Einstein Campus, Bronx, New York, United States

Montefiore Medical Center-Weiler Hospital, Bronx, New York, United States

Montefiore Medical Center - Moses Campus, Bronx, New York, United States

Arnot Ogden Medical Center/Falck Cancer Center, Elmira, New York, United States

Glens Falls Hospital, Glens Falls, New York, United States

Weill Medical College of Cornell University, New York, New York, United States

State University of New York Upstate Medical University, Syracuse, New York, United States

Faxton-Saint Luke's Healthcare, Utica, New York, United States

Randolph Hospital, Asheboro, North Carolina, United States

Asheville Hematology-Oncology Associates, Asheville, North Carolina, United States

Cone Health Cancer Center at Alamance Regional, Burlington, North Carolina, United States

Sampson Radiation Oncology, Clinton, North Carolina, United States

Southeastern Medical Oncology Center-Clinton, Clinton, North Carolina, United States

Duke University Medical Center, Durham, North Carolina, United States

Southeastern Medical Oncology Center-Goldsboro, Goldsboro, North Carolina, United States

Wayne Memorial Hospital, Goldsboro, North Carolina, United States

Wayne Radiation Oncology, Goldsboro, North Carolina, United States

Cone Health Cancer Center, Greensboro, North Carolina, United States

Hendersonville Hematology and Oncology at Pardee, Hendersonville, North Carolina, United States

Margaret R Pardee Memorial Hospital, Hendersonville, North Carolina, United States

Park Ridge Hospital Breast Health Center, Hendersonville, North Carolina, United States

Maria Parham Hospital, Henderson, North Carolina, United States

Onslow Memorial Hospital, Jacksonville, North Carolina, United States

Southeastern Medical Oncology Center-Jacksonville, Jacksonville, North Carolina, United States

Kinston Medical Specialists PA, Kinston, North Carolina, United States

Scotland Memorial Hospital-Laurinburg Cancer Center, Laurinburg, North Carolina, United States

Cone Heath Cancer Center at Mebane, Mebane, North Carolina, United States

Annie Penn Memorial Hospital, Reidsville, North Carolina, United States

Johnston Memorial Hospital, Smithfield, North Carolina, United States

Southeastern Medical Oncology Center-Wilson, Wilson, North Carolina, United States

Sanford Bismarck Medical Center, Bismarck, North Dakota, United States

Essentia Health Cancer Center-South University Clinic, Fargo, North Dakota, United States

Roger Maris Cancer Center, Fargo, North Dakota, United States

Sanford Clinic North-Fargo, Fargo, North Dakota, United States

Sanford Medical Center-Fargo, Fargo, North Dakota, United States

Akron General Medical Center, Akron, Ohio, United States

Strecker Cancer Center-Belpre, Belpre, Ohio, United States

Mercy Medical Center, Canton, Ohio, United States

Dayton Physicians LLC-Miami Valley South, Centerville, Ohio, United States

Miami Valley Hospital South, Centerville, Ohio, United States

Geaugra Hospital, Chardon, Ohio, United States

Adena Regional Medical Center, Chillicothe, Ohio, United States

Oncology Hematology Care Inc-Eden Park, Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Mercy West, Cincinnati, Ohio, United States

University of Cincinnati/Barrett Cancer Center, Cincinnati, Ohio, United States

Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio, United States

Oncology Hematology Care Inc - Anderson, Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Kenwood, Cincinnati, Ohio, United States

Bethesda North Hospital, Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Blue Ash, Cincinnati, Ohio, United States

TriHealth Cancer Institute-Westside, Cincinnati, Ohio, United States

TriHealth Cancer Institute-Anderson, Cincinnati, Ohio, United States

Case Western Reserve University, Cleveland, Ohio, United States

MetroHealth Medical Center, Cleveland, Ohio, United States

Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio, United States

Cleveland Clinic Foundation, Cleveland, Ohio, United States

Columbus Oncology and Hematology Associates Inc, Columbus, Ohio, United States

Riverside Methodist Hospital, Columbus, Ohio, United States

Grant Medical Center, Columbus, Ohio, United States

The Mark H Zangmeister Center, Columbus, Ohio, United States

Mount Carmel Health Center West, Columbus, Ohio, United States

Doctors Hospital, Columbus, Ohio, United States

Good Samaritan Hospital - Dayton, Dayton, Ohio, United States

Miami Valley Hospital, Dayton, Ohio, United States

Dayton Physicians LLC-Samaritan North, Dayton, Ohio, United States

Samaritan North Health Center, Dayton, Ohio, United States

Delaware Health Center-Grady Cancer Center, Delaware, Ohio, United States

Delaware Radiation Oncology, Delaware, Ohio, United States

Grady Memorial Hospital, Delaware, Ohio, United States

Mercy Cancer Center-Elyria, Elyria, Ohio, United States

Oncology Hematology Care Inc-Healthplex, Fairfield, Ohio, United States

Armes Family Cancer Center, Findlay, Ohio, United States

Blanchard Valley Hospital, Findlay, Ohio, United States

Orion Cancer Care, Findlay, Ohio, United States

Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio, United States

Dayton Physicians LLC-Atrium, Franklin, Ohio, United States

Dayton Physicians LLC-Wayne, Greenville, Ohio, United States

Wayne Hospital, Greenville, Ohio, United States

Cleveland Clinic Cancer Center Independence, Independence, Ohio, United States

Greater Dayton Cancer Center, Kettering, Ohio, United States

Kettering Medical Center, Kettering, Ohio, United States

Fairfield Medical Center, Lancaster, Ohio, United States

Saint Rita's Medical Center, Lima, Ohio, United States

Cleveland Clinic Cancer Center Mansfield, Mansfield, Ohio, United States

Marietta Memorial Hospital, Marietta, Ohio, United States

Toledo Clinic Cancer Centers-Maumee, Maumee, Ohio, United States

Toledo Radiation Oncology at Northwest Ohio Onocolgy Center, Maumee, Ohio, United States

Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio, United States

Lake University Ireland Cancer Center, Mentor, Ohio, United States

Southwest General Health Center Ireland Cancer Center, Middleburg Heights, Ohio, United States

Dayton Physicians LLC-Signal Point, Middletown, Ohio, United States

Knox Community Hospital, Mount Vernon, Ohio, United States

Licking Memorial Hospital, Newark, Ohio, United States

Newark Radiation Oncology, Newark, Ohio, United States

Saint Charles Hospital, Oregon, Ohio, United States

University Hospitals Parma Medical Center, Parma, Ohio, United States

Southern Ohio Medical Center, Portsmouth, Ohio, United States

Ireland Cancer Center at Firelands Regional Medical Center, Sandusky, Ohio, United States

North Coast Cancer Care, Sandusky, Ohio, United States

Dayton Physicians LLC-Wilson, Sidney, Ohio, United States

Springfield Regional Cancer Center, Springfield, Ohio, United States

Springfield Regional Medical Center, Springfield, Ohio, United States

Cleveland Clinic Cancer Center Strongsville, Strongsville, Ohio, United States

Flower Hospital, Sylvania, Ohio, United States

Mercy Saint Anne Hospital, Toledo, Ohio, United States

Toledo Clinic Cancer Centers-Toledo, Toledo, Ohio, United States

Dayton Physicians LLC-Upper Valley, Troy, Ohio, United States

Upper Valley Medical Center, Troy, Ohio, United States

University Hospitals Sharon Health Center, Wadsworth, Ohio, United States

South Pointe Hospital, Warrensville Heights, Ohio, United States

University Pointe, West Chester, Ohio, United States

Saint Ann's Hospital, Westerville, Ohio, United States

UH-Seidman Cancer Center at Saint John Medical Center, Westlake, Ohio, United States

Cleveland Clinic Wooster Family Health and Surgery Center, Wooster, Ohio, United States

Wright-Patterson Medical Center, Wright-Patterson Air Force Base, Ohio, United States

Genesis Healthcare System Cancer Care Center, Zanesville, Ohio, United States

Cancer Centers of Southwest Oklahoma Research, Lawton, Oklahoma, United States

Saint Charles Health System, Bend, Oregon, United States

Clackamas Radiation Oncology Center, Clackamas, Oregon, United States

Providence Oncology and Hematology Care Southeast, Clackamas, Oregon, United States

Bay Area Hospital, Coos Bay, Oregon, United States

Providence Newberg Medical Center, Newberg, Oregon, United States

Providence Willamette Falls Medical Center, Oregon City, Oregon, United States

Providence Portland Medical Center, Portland, Oregon, United States

Providence Saint Vincent Medical Center, Portland, Oregon, United States

Kaiser Permanente Northwest, Portland, Oregon, United States

Christiana Care Health System-Concord Health Center, Chadds Ford, Pennsylvania, United States

Geisinger Medical Center, Danville, Pennsylvania, United States

Doylestown Hospital, Doylestown, Pennsylvania, United States

PinnacleHealth Cancer Center-Community Campus, Harrisburg, Pennsylvania, United States

Geisinger Medical Center-Cancer Center Hazleton, Hazleton, Pennsylvania, United States

Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, United States

Geisinger Medical Oncology-Lewisburg, Lewisburg, Pennsylvania, United States

Lewistown Hospital, Lewistown, Pennsylvania, United States

University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania, United States

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States

Phoenixville Hospital, Phoenixville, Pennsylvania, United States

Geisinger Medical Oncology-Pottsville, Pottsville, Pennsylvania, United States

Guthrie Medical Group PC-Robert Packer Hospital, Sayre, Pennsylvania, United States

Hematology and Oncology Associates of North East Pennsylvania, Scranton, Pennsylvania, United States

Geisinger Medical Group, State College, Pennsylvania, United States

Reading Hospital, West Reading, Pennsylvania, United States

Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania, United States

Susquehanna Cancer Center, Williamsport, Pennsylvania, United States

Roper Hospital, Charleston, South Carolina, United States

Charleston Hematology Oncology Associates-Roper, Charleston, South Carolina, United States

Lowcountry Hematology Oncology PA-North Charleston, Charleston, South Carolina, United States

Bon Secours Saint Francis Hospital, Charleston, South Carolina, United States

Charleston Hematology Oncology Associates PA-St. Francis, Charleston, South Carolina, United States

Lowcountry Hematology Oncology PA-West Ashley, Charleston, South Carolina, United States

Greenville Health System Cancer Institute-Easley, Easley, South Carolina, United States

Saint Francis Hospital, Greenville, South Carolina, United States

Greenville Health System Cancer Institute-Andrews, Greenville, South Carolina, United States

Greenville Health System Cancer Institute-Butternut, Greenville, South Carolina, United States

Greenville Health System Cancer Institute-Faris, Greenville, South Carolina, United States

Greenville Memorial Hospital, Greenville, South Carolina, United States

Saint Francis Cancer Center, Greenville, South Carolina, United States

Greenville Health System Cancer Institute-Eastside, Greenville, South Carolina, United States

Greenville Health System Cancer Institute-Greer, Greer, South Carolina, United States

Lowcountry Hematology Oncology PA-Mount Pleasant, Mount Pleasant, South Carolina, United States

Greenville Health System Cancer Institute-Seneca, Seneca, South Carolina, United States

Greenville Health System Cancer Institute-Spartanburg, Spartanburg, South Carolina, United States

Sanford Cancer Center-Oncology Clinic, Sioux Falls, South Dakota, United States

Avera Cancer Institute, Sioux Falls, South Dakota, United States

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota, United States

Memorial Hospital, Chattanooga, Tennessee, United States

Pulmonary Medicine Center of Chattanooga-Hixson, Hixson, Tennessee, United States

Thompson Cancer Survival Center, Knoxville, Tennessee, United States

Meharry Medical College, Nashville, Tennessee, United States

Memorial GYN Plus, Ooltewah, Tennessee, United States

M D Anderson Cancer Center, Houston, Texas, United States

Scott and White Healthcare Round Rock, Round Rock, Texas, United States

University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States

Scott and White Memorial Hospital, Temple, Texas, United States

Central Vermont Medical Center/National Life Cancer Treatment, Berlin, Vermont, United States

University of Vermont Medical Center, Burlington, Vermont, United States

University of Vermont College of Medicine, Burlington, Vermont, United States

Providence Regional Cancer System-Aberdeen, Aberdeen, Washington, United States

Cancer Care Center at Island Hospital, Anacortes, Washington, United States

MultiCare Auburn Medical Center, Auburn, Washington, United States

Virginia Mason Bainbridge Island Medical Center, Bainbridge Island, Washington, United States

Overlake Hospital Medical Center, Bellevue, Washington, United States

Swedish Cancer Institute-Eastside Oncology Hematology, Bellevue, Washington, United States

PeaceHealth Saint Joseph Medical Center, Bellingham, Washington, United States

Harrison HealthPartners Hematology and Oncology-Bremerton, Bremerton, Washington, United States

Harrison Medical Center, Bremerton, Washington, United States

Highline Medical Center-Main Campus, Burien, Washington, United States

Providence Regional Cancer System-Centralia, Centralia, Washington, United States

Swedish Medical Center-Edmonds, Edmonds, Washington, United States

Saint Elizabeth Hospital, Enumclaw, Washington, United States

Providence Regional Cancer Partnership, Everett, Washington, United States

Virginia Mason Federal Way Medical Center, Federal Way, Washington, United States

Saint Francis Hospital, Federal Way, Washington, United States

Tacoma/Valley Radiation Oncology Centers-Gig Harbor, Gig Harbor, Washington, United States

MultiCare Gig Harbor Medical Park, Gig Harbor, Washington, United States

Swedish Cancer Institute-Issaquah, Issaquah, Washington, United States

Kadlec Clinic Hematology and Oncology, Kennewick, Washington, United States

Northwest Cancer Clinic, Kennewick, Washington, United States

Seattle Cancer Care Alliance at EvergreenHealth, Kirkland, Washington, United States

Providence Regional Cancer System-Lacey, Lacey, Washington, United States

Saint Clare Hospital, Lakewood, Washington, United States

PeaceHealth Saint John Medical Center, Longview, Washington, United States

Virginia Mason Lynnwood Medical Center, Lynnwood, Washington, United States

Skagit Valley Hospital Regional Cancer Care Center, Mount Vernon, Washington, United States

Skagit Valley Hospital, Mount Vernon, Washington, United States

Olympic Medical Center, Port Angeles, Washington, United States

Jefferson Healthcare, Port Townsend, Washington, United States

Harrison HealthPartners Hematology and Oncology-Poulsbo, Poulsbo, Washington, United States

Peninsula Cancer Center, Poulsbo, Washington, United States

MultiCare Good Samaritan Hospital, Puyallup, Washington, United States

Tacoma/Valley Radiation Oncology Centers-Puyallup, Puyallup, Washington, United States

Virginia Mason Medical Center, Seattle, Washington, United States

Minor and James Medical PLLC, Seattle, Washington, United States

Pacific Gynecology Specialists, Seattle, Washington, United States

Swedish Medical Center-Ballard Campus, Seattle, Washington, United States

Fred Hutchinson Cancer Research Center, Seattle, Washington, United States

Seattle Cancer Care Alliance, Seattle, Washington, United States

Group Health Cooperative-Seattle, Seattle, Washington, United States

Swedish Medical Center-First Hill, Seattle, Washington, United States

University of Washington Medical Center, Seattle, Washington, United States

Olympic Medical Cancer Care Center, Sequim, Washington, United States

Providence Regional Cancer System-Shelton, Shelton, Washington, United States

Rockwood Clinic Cancer Treatment Center-Valley, Spokane Valley, Washington, United States

Cancer Care Northwest - Spokane South, Spokane, Washington, United States

Rockwood Cancer Treatment Center-DHEC-Downtown, Spokane, Washington, United States

Spokane Valley Cancer Center-Mayfair, Spokane, Washington, United States

Cancer Care Northwest-Valley, Spokane, Washington, United States

Cancer Care Northwest-North Spokane, Spokane, Washington, United States

Tacoma/Valley Radiation Oncology Centers-Jackson Hall, Tacoma, Washington, United States

Franciscan Research Center-Northwest Medical Plaza, Tacoma, Washington, United States

MultiCare Tacoma General Hospital, Tacoma, Washington, United States

Northwest Medical Specialties PLLC, Tacoma, Washington, United States

Northwest NCI Community Oncology Research Program, Tacoma, Washington, United States

Tacoma/Valley Radiation Oncology Centers-Saint Joe's, Tacoma, Washington, United States

PeaceHealth Southwest Medical Center, Vancouver, Washington, United States

Providence Saint Mary Regional Cancer Center, Walla Walla, Washington, United States

Wenatchee Valley Hospital and Clinics, Wenatchee, Washington, United States

North Star Lodge Cancer Center at Yakima Valley Memorial Hospital, Yakima, Washington, United States

Providence Regional Cancer System-Yelm, Yelm, Washington, United States

West Virginia University Charleston, Charleston, West Virginia, United States

Langlade Hospital and Cancer Center, Antigo, Wisconsin, United States

Marshfield Clinic-Chippewa Center, Chippewa Falls, Wisconsin, United States

Marshfield Clinic Cancer Center at Sacred Heart, Eau Claire, Wisconsin, United States

Green Bay Oncology at Saint Vincent Hospital, Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin, United States

Green Bay Oncology Limited at Saint Mary's Hospital, Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin, United States

Gundersen Lutheran Medical Center, La Crosse, Wisconsin, United States

Holy Family Memorial Hospital, Manitowoc, Wisconsin, United States

Marshfield Clinic, Marshfield, Wisconsin, United States

Wheaton Franciscan Healthcare - Saint Joseph, Milwaukee, Wisconsin, United States

Marshfield Clinic-Minocqua Center, Minocqua, Wisconsin, United States

ProHealth D N Greenwald Center, Mukwonago, Wisconsin, United States

Cancer Center of Western Wisconsin, New Richmond, Wisconsin, United States

ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin, United States

Green Bay Oncology - Oconto Falls, Oconto Falls, Wisconsin, United States

Marshfield Clinic-Rice Lake Center, Rice Lake, Wisconsin, United States

HSHS Saint Nicholas Hospital, Sheboygan, Wisconsin, United States

Marshfield Clinic Cancer Care at Saint Michael's Hospital, Stevens Point, Wisconsin, United States

Green Bay Oncology - Sturgeon Bay, Sturgeon Bay, Wisconsin, United States

ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin, United States

UW Cancer Center at ProHealth Care, Waukesha, Wisconsin, United States

Aspirus Regional Cancer Center, Wausau, Wisconsin, United States

Marshfield Clinic-Wausau Center, Wausau, Wisconsin, United States

Marshfield Clinic - Weston Center, Weston, Wisconsin, United States

Aspirus UW Cancer Center, Wisconsin Rapids, Wisconsin, United States

Marshfield Clinic - Wisconsin Rapids Center, Wisconsin Rapids, Wisconsin, United States

Cheyenne Regional Medical Center-West, Cheyenne, Wyoming, United States

Contact Details

Name: Edmund S Kopetz, M.D.

Affiliation: M.D. Anderson

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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