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Brief Title: Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer
Official Title: Evaluating a Surgical-Sparing Approach Using Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer
Study ID: NCT06205836
Brief Summary: The purpose of this study is to evaluate the safety and clinical activity of cemiplimab and the combination of cemiplimab/fianlimab in microsatellite unstable localized or locally advanced colorectal cancer diagnosed in patients age 70 or greater.
Detailed Description:
Minimum Age: 70 Years
Eligible Ages: OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Johns Hopkins SKCCC, Baltimore, Maryland, United States
Name: Eric Christenson, MD
Affiliation: Sidney Kimmel Comprehensive Cancer Center Johns Hopkins Medical Institution
Role: PRINCIPAL_INVESTIGATOR