Spots Global Cancer Trial Database for The Effect of Ketamine on Immune Function and Prognosis in Patients Undergoing Colorectal Cancer Resection
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Trial Identification
Brief Title: The Effect of Ketamine on Immune Function and Prognosis in Patients Undergoing Colorectal Cancer Resection
Official Title: The Effect of Ketamine on Immune Function and Prognosis in Patients Undergoing Colorectal Cancer Resection
Study ID: NCT03273231
Conditions
Study Description
Brief Summary: Systemic inflammation caused by surgery may aggravate immunosuppression in immunocompromised cancer patients. The natural killer (NK) cell is a critical part of anti-tumor immunity. ketamine, a N-methyl-D-asparate receptor antangonist, has anti-inflammatory activity and opioid-sparing effect. This study investigate the effect of intraopertaive ketamine administration on immune function in patients undergoing laparoscopic colorectal cancer resection.
Detailed Description:
Keywords
Eligibility
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, , Korea, Republic of
Contact Details
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