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Brief Title: Prevalence and Topography of Adenomas in 40-49 Year Old Patients With a Family History of Colon Cancer
Official Title: Prevalence and Topography of Adenomas in 40-49 Year Old Patients With a Family History of Colon Cancer
Study ID: NCT02289053
Brief Summary: Conflicting guideline recommendations for screening colonoscopy result due to scant data upon which to develop appropriate recommendations. No previous study has compared the prevalence of advanced adenomas or adenomas (any size) among 40-49 year old individuals with a first degree relative (FDR) with colorectal cancer (CRC) versus 40-49 year old average risk individuals with no family history of CRC. The purpose of this study is to determine the prevalence of colon adenomas in 40-49 year old individuals and identify risk factors associated with the presence of advanced adenomas. This data will provide evidence to determine appropriate colon cancer screening guidelines in 40-49 year old persons with a family history of colon polyps or colorectal cancer.
Detailed Description:
Minimum Age: 40 Years
Eligible Ages: ADULT
Sex: ALL
Healthy Volunteers: Yes
Walter Reed National Military Medical Center, Bethesda, Maryland, United States
Ann Arbor VA Healthcare System, Ann Arbor, Michigan, United States
University of Michigan, Ann Arbor, Michigan, United States
John D. Dingell VA Medical Center, Detroit, Michigan, United States
Huron Gastro, Ypsilanti, Michigan, United States
Durham VA Medical Center, Durham, North Carolina, United States
Name: Philip Schoenfeld, MD
Affiliation: University of Michigan
Role: PRINCIPAL_INVESTIGATOR