Spots Global Cancer Trial Database for Preoperative Non-steroidal Anti-inflammatory Drugs(NSAID) to Colorectal Cancer Patients
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Trial Identification
Brief Title: Preoperative Non-steroidal Anti-inflammatory Drugs(NSAID) to Colorectal Cancer Patients
Official Title: Preoperative Treatment With NSAID in Colorectal Cancer Patients in Relationship to Tumor Host Reactions
Study ID: NCT00473980
Conditions
Interventions
Study Description
Brief Summary: The study is designed to evaluate effects of NSAIDs on immune activity inside and close to tumor tissue in patients with colorectal cancer.
Detailed Description: Study and control patients are randomized to receive preoperative treatment with indomethacin or celecoxib compared to sham treatment.Tumor biopsies are taken at operation and used for analyses of tumor immunity and gene expression.
Eligibility
Minimum Age: 40 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Department of Surgery, Göteborg, , Sweden
Contact Details
Name: Kent Lundholm, MD, prof
Affiliation: Göteborg University
Role: PRINCIPAL_INVESTIGATOR
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