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Brief Title: A Trial to Evaluate Laparoscopic Versus Open Surgery for Colorectal Cancer
Official Title: Randomized Controlled Trial to Evaluate Laparoscopic Versus Open Surgery for Colorectal Cancer(JCOG 0404,CRC Surg-LAP/OPEN)
Study ID: NCT00147134
Brief Summary: The purpose of this study is to evaluate oncological outcome of patients for T3 and T4 colorectal cancer undergoing laparoscopic versus open surgery.
Detailed Description: The benefits of laparoscopic surgery (LAP) in comparison to open surgery (OPEN) have been suggested with respect to decreased morbidity, decreased pain, faster recovery, and shorter hospital stay.1-4 However, the long-term survival of LAP for colorectal cancer is still unclear, especially for advanced colorectal cancer requiring extended lymphadenectomy. Thus, the investigators designed a study which investigates whether LAP is suitable for advanced colorectal cancer with respect to survival and post-operative morbidity.
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Fujita Health University, Toyoake,Kutsukake-cho,Dengakugakubo,1-98, Aichi, Japan
National Cancer Center Hospital East, Kashiwa,Kashiwanoha,6-5-1, Chiba, Japan
Toho University Sakura Hospital, Sakura,Shimoshidu,564-1, Chiba, Japan
Jyuntendo Urayasu Hospital, Urayasu,Tomioka,2-1-1, Chiba, Japan
National Hospital Organization Shikoku Cancer Center, Matsuyama,Horinouchi,13, Ehime, Japan
Kurume University School of Medicine, Kurume,Asahi-machi,67, Fukuoka, Japan
Hiroshima University, School of Medicine, Hiroshima,Minami-ku,Kasumi,1-2-3, Hiroshima, Japan
Ishikawa Prefectual Central Hospital, Kanazawa,Kuratsuki-Higashi,2-1, Ishikawa, Japan
Teikyo University Hospital, Mizonokuchi, Kawasaki,Takatsu-ku,Mizonokuchi,3-8-3, Kanagawa, Japan
Kitasato University East Hospital, Sagamihara,Asamizodai,2-1-1, Kanagawa, Japan
Kitasato University School of Medichine, Sagamihara,Kitasato,1-15-1, Kanagawa, Japan
Showa University Northern Yokohama Hospital, Yokohama,Tsuzuki-ku,Chigasakichuo,35-1, Kanagawa, Japan
National Hospital Organization Kyoto Medical Center, Kyoto,Fushimi-ku,Fukakusa,Mukaihata-cho,1-1, Kyoto, Japan
Nagano Municipal Hospital, Nagano,Tomitake,1333-1, Nagano, Japan
Oita University Faculty of Medicine, Yufu city,Hasama-machi, 1-1, Oita, Japan
Osaka City General Hospital, Osaka,Miyakojima-ku,Miyakojimahondori,2-13-22, Osaka, Japan
Osaka University Graduate School of Medicine, Suita,Yamada-oka,2-2, Osaka, Japan
Osaka Medical College, Takatsuki,Daigakucho,2-7, Osaka, Japan
Omiya Medical Center, Jichi Medical School, Saitama,Omiya-ku,Amanuma-cho,1-847, Saitama, Japan
Sizuoka Cancer Center, Sunto-gun,Nagaizumi-cho,Shimonagakubo,1007, Shizuoka, Japan
Tokyo Medical and Dental University Hospital, Bunkyo-ku,Yushima,1-5-45, Tokyo, Japan
National Cancer Center Hospital, Chuo-ku,Tsukiji,5-1-1, Tokyo, Japan
Toho University Ohashi Hospital, Meguro-ku,Ohashi,2-17-6, Tokyo, Japan
Toranomon Hospital, Minato-ku,Toranomon,2-2-2, Tokyo, Japan
Kyorin University School of Medicine, Mitaka,Shinkawa,6-20-2, Tokyo, Japan
Keio University Hospital, Shinjuku-ku,Shinanomachi,35, Tokyo, Japan
Name: Seigo Kitano, MD, PhD,FACS
Affiliation: Oita University
Role: STUDY_CHAIR