Spots Global Cancer Trial Database for Colorectal Cancer Screening for Cancer Survivors
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Trial Identification
Brief Title: Colorectal Cancer Screening for Cancer Survivors
Official Title: Colorectal Cancer Screening in Cancer Survivors Treated With Radiation Therapy
Study ID: NCT00982059
Conditions
Interventions
Study Description
Brief Summary: The risk of colorectal cancer (CRC) is significant among cancer survivors treated with abdominal radiation therapy (RT). Further, CRC is once of the few cancers for which there is effective screening. Although some expert groups recommend early CRC screening for patients with prior abdominal RT, the effectiveness of early screening is unknown. It is also unknown if radiation-induced CRC passes through a "pre-clinical" phase in which precancerous polyps are detectable and treatable prior to becoming invasive cancers. This study will evaluate whether screening will detect pre-invasive colorectal polyps among survivors treated with RT.
Detailed Description: Cancer survivors meeting the COG criteria for CRC screening will undergo colonoscopy and removal of colorectal polyps. Documentation of polyp number, location and pathologic characteristics will be made. Clinical data information will also be collected at the time of patient enrollment.
Eligibility
Minimum Age: 35 Years
Eligible Ages: ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
University Health Network, Toronto, Ontario, Canada
Contact Details
Name: David Hodgson, MD
Affiliation: University Health Network, Princess Margaret Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Andrea K Ng, MD
Affiliation: Dana-Farber Cancer Institute
Role: PRINCIPAL_INVESTIGATOR
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