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Spots Global Cancer Trial Database for Laparoscopic-Assisted Surgery Compared With Open Surgery in Treating Patients With Colon Cancer

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Trial Identification

Brief Title: Laparoscopic-Assisted Surgery Compared With Open Surgery in Treating Patients With Colon Cancer

Official Title: A PHASE III PROSPECTIVE RANDOMIZED TRIAL COMPARING LAPAROSCOPIC-ASSISTED COLECTOMY VERSUS OPEN COLECTOMY FOR COLON CANCER

Study ID: NCT00002575

Study Description

Brief Summary: RATIONALE: Less invasive types of surgery may help reduce the number of side effects and improve recovery. It is not yet known which type of surgery is more effective for colon cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of laparoscopic-assisted colectomy with open colectomy in treating patients who have colon cancer.

Detailed Description: OBJECTIVES: * Compare the disease-free and overall survival rates of patients with colon cancer treated with laparoscopic-assisted colectomy vs open colectomy. * Compare the safety of these regimens in terms of early and late morbidity and 30-day mortality of these patients. * Compare the differences in costs and cost effectiveness between these treatments in this patient population. * Compare the differences in quality of life of patients treated with these regimens. (closed as of 4/30/99) OUTLINE: This is a randomized, multicenter study. Patients are stratified according to participating center, primary surgeon, site of primary tumor (right vs left vs sigmoid), and American Society of Anesthesiologists disease classification (I and II vs III). Patients are randomized to one of two treatment arms. The extent of colon resection is identical for both arms.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Huntsville Hospital System, Huntsville, Alabama, United States

MBCCOP - Gulf Coast, Mobile, Alabama, United States

CCOP - Greater Phoenix, Phoenix, Arizona, United States

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

St. Mary's Hospital, Rogers, Arkansas, United States

Cancer Center and Beckman Research Institute, City of Hope, Duarte, California, United States

Scripps Clinic, La Jolla, California, United States

University of California San Diego Cancer Center, La Jolla, California, United States

Loma Linda University Medical Center, Loma Linda, California, United States

Saint Mary Medical Center - Long Beach, Long Beach, California, United States

CCOP - Bay Area Tumor Institute, Oakland, California, United States

Naval Medical Center - Oakland, Oakland, California, United States

Sutter Cancer Center, Sacramento, California, United States

Veterans Affairs Satellite Clinic - Sacramento, Sacramento, California, United States

Naval Medical Center - San Diego, San Diego, California, United States

Veterans Affairs Medical Center - San Francisco, San Francisco, California, United States

CCOP - Santa Rosa Memorial Hospital, Santa Rosa, California, United States

Kaiser Permanente Medical Center - Vallejo, Vallejo, California, United States

University of Colorado Cancer Center, Denver, Colorado, United States

CCOP - Colorado Cancer Research Program, Inc., Denver, Colorado, United States

Hartford Hospital, Hartford, Connecticut, United States

CCOP - Christiana Care Health Services, Wilmington, Delaware, United States

Baptist Regional Cancer Institute - Jacksonville, Jacksonville, Florida, United States

CCOP - Mount Sinai Medical Center, Miami Beach, Florida, United States

Sylvester Cancer Center, University of Miami, Miami, Florida, United States

MD Anderson Cancer Center Orlando, Orlando, Florida, United States

Sarasota Memorial Hospital, Sarasota, Florida, United States

Winship Cancer Institute, Atlanta, Georgia, United States

CCOP - Atlanta Regional, Atlanta, Georgia, United States

Medical College of Georgia Comprehensive Cancer Center, Augusta, Georgia, United States

Veterans Affairs Medical Center - Atlanta (Decatur), Decatur, Georgia, United States

Cancer Research Center of Hawaii, Honolulu, Hawaii, United States

Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, United States

Veterans Affairs Medical Center - Lakeside Chicago, Chicago, Illinois, United States

MBCCOP-Cook County Hospital, Chicago, Illinois, United States

Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, United States

Illinois Masonic Medical Center, Chicago, Illinois, United States

CCOP - Central Illinois, Decatur, Illinois, United States

CCOP - Evanston, Evanston, Illinois, United States

West Suburban Hospital Medical Center, Oak Park, Illinois, United States

Rockford Clinic, Rockford, Illinois, United States

CCOP - Carle Cancer Center, Urbana, Illinois, United States

Regional Cancer Center, Indianapolis, Indiana, United States

CCOP - Iowa Oncology Research Association, Des Moines, Iowa, United States

Holden Comprehensive Cancer Center, Iowa City, Iowa, United States

CCOP - Wichita, Wichita, Kansas, United States

Lucille Parker Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States

Norton Healthcare System, Louisville, Kentucky, United States

Baptist Hospital East - Louisville, Louisville, Kentucky, United States

Louisiana State University Medical Center - New Orleans, New Orleans, Louisiana, United States

Tulane University School of Medicine, New Orleans, Louisiana, United States

Veterans Affairs Medical Center - New Orleans, New Orleans, Louisiana, United States

CCOP - Ochsner, New Orleans, Louisiana, United States

Eastern Maine Medical Center, Bangor, Maine, United States

Franklin Square Hospital Center, Baltimore, Maryland, United States

National Naval Medical Center, Bethesda, Maryland, United States

Regional Cancer Therapy Center - Frederick, Frederick, Maryland, United States

New England Medical Center Hospital, Boston, Massachusetts, United States

Boston Medical Center, Boston, Massachusetts, United States

Lahey Clinic - Burlington, Burlington, Massachusetts, United States

Berkshire Medical Center, Pittsfield, Massachusetts, United States

Baystate Medical Center, Springfield, Massachusetts, United States

University of Massachusetts Memorial Healthcare, Worester, Massachusetts, United States

CCOP - Ann Arbor Regional, Ann Arbor, Michigan, United States

Michigan State University, East Lansing, Michigan, United States

CCOP - Grand Rapids Clinical Oncology Program, Grand Rapids, Michigan, United States

CCOP - Kalamazoo, Kalamazoo, Michigan, United States

Providence Hospital - Southfield, Southfield, Michigan, United States

CCOP - Duluth, Duluth, Minnesota, United States

Hennepin County Medical Center - Minneapolis, Minneapolis, Minnesota, United States

CCOP - Metro-Minnesota, Saint Louis Park, Minnesota, United States

Keesler Medical Center - Keesler AFB, Keesler AFB, Mississippi, United States

Ellis Fischel Cancer Center - Columbia, Columbia, Missouri, United States

CCOP - Kansas City, Kansas City, Missouri, United States

St. Louis University School of Medicine, Saint Louis, Missouri, United States

CCOP - St. Louis-Cape Girardeau, Saint Louis, Missouri, United States

CCOP - Montana Cancer Consortium, Billings, Montana, United States

CCOP - Missouri Valley Cancer Consortium, Omaha, Nebraska, United States

Methodist Cancer Center - Omaha, Omaha, Nebraska, United States

CCOP - Southern Nevada Cancer Research Foundation, Las Vegas, Nevada, United States

Veterans Affairs Medical Center - East Orange, East Orange, New Jersey, United States

CCOP - Northern New Jersey, Hackensack, New Jersey, United States

Newark Beth Israel Medical Center, Newark, New Jersey, United States

University of New Mexico Cancer Research & Treatment Center, Albuquerque, New Mexico, United States

Albany Regional Cancer Center, Albany, New York, United States

CCOP - North Shore University Hospital, Manhasset, New York, United States

Champlain Valley Physicians Hospital Medical Center, Plattsburgh, New York, United States

Genesee Surgical Associates, Rochester, New York, United States

Staten Island University Hospital, Staten Island, New York, United States

CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C., Syracuse, New York, United States

Lineberger Comprehensive Cancer Center, UNC, Chapel Hill, North Carolina, United States

CCOP - Southeast Cancer Control Consortium, Winston-Salem, North Carolina, United States

Comprehensive Cancer Center at Wake Forest University, Winston-Salem, North Carolina, United States

Veterans Affairs Medical Center - Fargo, Fargo, North Dakota, United States

CCOP - Merit Care Hospital, Fargo, North Dakota, United States

Akron City Hospital, Akron, Ohio, United States

Aultman Cancer Center, Canton, Ohio, United States

Jewish Hospital of Cincinnati, Inc., Cincinnati, Ohio, United States

Barrett Cancer Center, The University Hospital, Cincinnati, Ohio, United States

South Pointe Hospital, Cleveland, Ohio, United States

CCOP - Columbus, Columbus, Ohio, United States

Arthur G. James Cancer Hospital - Ohio State University, Columbus, Ohio, United States

Veterans Affairs Medical Center - Dayton, Dayton, Ohio, United States

CCOP - Dayton, Kettering, Ohio, United States

CCOP - Toledo Community Hospital Oncology Program, Toledo, Ohio, United States

CCOP - Oklahoma, Tulsa, Oklahoma, United States

Oregon Cancer Center, Portland, Oregon, United States

CCOP - Columbia River Program, Portland, Oregon, United States

Lehigh Valley Hospital, Allentown, Pennsylvania, United States

St. Luke's Network - Bethlehem, Bethlehem, Pennsylvania, United States

Geisinger Medical Center, Danville, Pennsylvania, United States

Albert Einstein Cancer Center, Philadelphia, Pennsylvania, United States

Allegheny General Hospital, Pittsburgh, Pennsylvania, United States

University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States

Veterans Affairs Medical Center - Pittsburgh, Pittsburgh, Pennsylvania, United States

Reading Hospital and Medical Center, Reading, Pennsylvania, United States

CCOP - MainLine Health, Wynnewood, Pennsylvania, United States

York Hospital, York, Pennsylvania, United States

Kent County Memorial Hospital, Warwick, Rhode Island, United States

Medical University of South Carolina, Charleston, South Carolina, United States

CCOP - Greenville, Greenville, South Carolina, United States

CCOP - Upstate Carolina, Spartanburg, South Carolina, United States

CCOP - Sioux Community Cancer Consortium, Sioux Falls, South Dakota, United States

Baptist Regional Cancer Center - Knoxville, Knoxville, Tennessee, United States

Veterans Affairs Medical Center - Memphis, Memphis, Tennessee, United States

Medical Group of Texas, Dallas, Texas, United States

Kelsey Seybold Clinic, Houston, Texas, United States

Wilford Hall - 59th Medical Wing, Lackland Air Force Base, Texas, United States

University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States

University of Texas Health Center at Tyler, Tyler, Texas, United States

Utah Valley Regional Medical Center - Provo, Provo, Utah, United States

Vermont Cancer Center, Burlington, Vermont, United States

Virginia Oncology Associates - Newport News, Newport News, Virginia, United States

Eastern Virginia Medical School, Norfolk, Virginia, United States

Veterans Affairs Medical Center - Richmond, Richmond, Virginia, United States

Massey Cancer Center, Richmond, Virginia, United States

MBCCOP - Massey Cancer Center, Richmond, Virginia, United States

Oncology and Hematology Associates of Southwest Virginia, Inc., Roanoke, Virginia, United States

CCOP - Virginia Mason Research Center, Seattle, Washington, United States

Puget Sound Oncology Consortium, Seattle, Washington, United States

CCOP - Northwest, Tacoma, Washington, United States

Camden-Clark Memorial Hospital, Parkersburg, West Virginia, United States

CCOP - Green Bay, Green Bay, Wisconsin, United States

CCOP - Marshfield Medical Research and Education Foundation, Marshfield, Wisconsin, United States

Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Tom Baker Cancer Center - Calgary, Calgary, Alberta, Canada

Cross Cancer Institute, Edmonton, Alberta, Canada

CancerCare Manitoba, Winnipeg, Manitoba, Canada

Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario, Canada

St. Michael's Hospital - Toronto, Toronto, Ontario, Canada

Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec, Canada

Royal Victoria Hospital - Montreal, Montreal, Quebec, Canada

Montreal General Hospital, Montreal, Quebec, Canada

Jewish General Hospital - Montreal, Montreal, Quebec, Canada

Centre Hospitalier Universitaire de Quebec, Quebec City, Quebec, Canada

L'Hopital Laval, Ste-Foy, Quebec, Canada

MBCCOP - San Juan, San Juan, , Puerto Rico

Veterans Affairs Medical Center - San Juan, San Juan, , Puerto Rico

Contact Details

Name: Heidi Nelson, MD

Affiliation: Mayo Clinic

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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