Spots Global Cancer Trial Database for Multimodal Assessment of Liver Volume and Function
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Trial Identification
Brief Title: Multimodal Assessment of Liver Volume and Function
Official Title: Multimodal Assessment of Liver Volume and Function in Patients With Colorectal Liver Metastases
Study ID: NCT03140917
Interventions
Study Description
Brief Summary: In liver surgery peroperative assessment och the future liver remnant (FLR) is pivotal in order to avoid posthepatectomy liver failure. To date this is mainly performed by measuring the volume of the FLR. Of course FLR volume acts as a surrogate measure of FLR function and the correlation between volume and function is not always accurate. Several techniques to assess FLR function has been proposed. Hepatobiliary scintigraphy (HBS) and Dynamic MRI are the two such methods. In this study we compare HBS and MRI, in addition to contrast-enhanced CT and ICG, repeatedly performed before and after right hepatectomy in patients with colorectal liver metastases treated with neoadjuvant chemotherapy.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Karolinska University Hospital, Stockholm, , Sweden
Contact Details
Name: Magnus Nilsson, MD PhD
Affiliation: Karolinska Institutet
Role: STUDY_CHAIR
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