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Brief Title: Efficacy of Cap-assisted Chromoendoscopy as a Screening Test for Colorectal Neoplasm Using Web-based Research Network
Official Title: Prospective Randomized Controlled Trial of Cap-Assisted ChromoEndoscopy(CapACE) Versus Conventional Colonoscopy(CC) for the Detection of Colorectal Neoplasia
Study ID: NCT01112280
Brief Summary: The investigators plan to conduct a multi-center, randomized controlled trial to investigate the efficacy of cap-assisted chromoendoscopy as a screening test for detection of colorectal polyp. This study will be performed using web-based research network, e-VELOS in Korea.
Detailed Description: Various endoscopic tools have been tried to reduce polyp missing rate which has been reported to be 20-25%. Transparent cap-assisted colonoscopy has been suggested to improve visualization of the lesion that are difficult to access, such as tangentially located lesions and those located within a limited luminal space. Chromoendoscopy with indigocarmine spraying was reported to increases the detection rates of polyp, especially in right colon and rectum. However, there also have been mixed results regarding polyp detection rates of the endoscopic methods. Moreover, there is no data regarding the impact of the screening tools on longterm recurrence rate of colorectal polyp. Therefore, in this study, we intend to perform a multi-center, randomized controlled trial to investigate the efficacy of cap-assisted chromoendoscopy as a screening test for detection of colorectal polyps. This study will be performed using web-based research network, e-VELOS in Korea.
Minimum Age: 45 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Hallym University Medical Center, Anyang, , Korea, Republic of
Kosin University College of Medicine, Busan, , Korea, Republic of
Dankuk University college of medicine hospital, Cheonan, , Korea, Republic of
National Cancer Center Hospital, National Cancer Center, Goyang, , Korea, Republic of
Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri-si, , Korea, Republic of
Catholic university St. Mari's hospital, Incheon, , Korea, Republic of
Asan Medical Center, University of Ulsan College of Medicine, Seoul, , Korea, Republic of
Ewha Mokdong hospital, Seoul, , Korea, Republic of
Kyung Hee University Hospital at Gang Dong, Kyung Hee University School of Medicine, Seoul, , Korea, Republic of
Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, , Korea, Republic of
Sunchunhyang University hospital, Seoul, , Korea, Republic of
Sungkyunkwan University Kangbuk Samsung hospital, Seoul, , Korea, Republic of
Yonsei University College of Medicine, Seoul, , Korea, Republic of
Yonsei Uiniversity Wonju College of Medicine, Wonju, , Korea, Republic of
Name: Hyun Soo Kim
Affiliation: Korean Association for the Study of Intestinal Diseases
Role: PRINCIPAL_INVESTIGATOR