Spots Global Cancer Trial Database for Outcomes of Perforation After Colorectal Endoscopic Submucosal Dissection

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Trial Identification

Brief Title: Outcomes of Perforation After Colorectal Endoscopic Submucosal Dissection

Official Title: Outcomes of Perforation After Colorectal Endoscopic Submucosal Dissection

Study ID: NCT05728710

Conditions

Colorectal Neoplasms

Perforation of Rectum

Perforation Colon

Interventions

Endoscopic submucosal dissection

Study Description

Brief Summary: Endoscopic resection of superficial colorectal neoplasms decrease risk of colorectal cancer. En bloc resection is necessary for large superficial lesions with risk of superficial submucosal cancer and is advised if feasible for all lesions. Endoscopic submucosal dissection (ESD) allows en bloc resection of large superficial colorectal neoplasms, increasing curative resection rate and decreasing local recurrence risk. However, the risk of perprocedural or delayed perforation is higher compared to wild field piece meal endoscopic mucosal resection. Endoscoping clipping and closing methods mostly allow conservative treatment, but some case still necessitate surgery. The aim of our study is to describe and ananalyse outcomes after perprocedural or delayed perforation in all patients undergoing ESD and analyse the need for surgical intervention.

Detailed Description: