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Spots Global Cancer Trial Database for Impact of Proximal Colon Retroflexion in Colorectal Cancer Screening Programme

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Trial Identification

Brief Title: Impact of Proximal Colon Retroflexion in Colorectal Cancer Screening Programme

Official Title: Impact of Proximal Colon Retroflexion in Colorectal Cancer Screening Programme: Randomized Trial

Study ID: NCT03041532

Study Description

Brief Summary: Colorectal cancer (CRC) is the most common tumor and the second leading cause of death in the Western world. The decrease in incidence and mortality by CRC in the population undergoing screening has been observed. Colonoscopy is the recommended method for detecting tumors in early stages, as well as identifying and resecting adenomatous polyps, which are the precursor lesions of most CRCs. Colonoscopy should be of high quality to decrease incidence and mortality by CRC and avoid interval cancer. The literature shows that colonoscopy does not prevent right colon lesions in the same way as the left colon lesions, with most of the interval cancers located in the right colon. Studies published so far show an increase in the adenomas detection rate (ADT) in the right colon in the second visualization of this segment and an increase between 2 and 10% if this second examination is performed with the proximal retroflexion maneuver.Retroflexion is a safe maneuver in expert endoscopists. The aim of our study is to evaluate the ADT in the right colon by means of a second visualization by performing proximal retroflexion or second frontal visualization at random in the CCR screening population.

Detailed Description:

Eligibility

Minimum Age: 50 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Hospital Universitario Rio Hortega, Valladolid, , Spain

Contact Details

Name: Mª Henar Núñez Rodriguez

Affiliation: Hospital del Rio Hortega Valladolid, Spain

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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