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Brief Title: A Study Combining FOLFOX or FOLFIRI With AG-013736 or Bevacizumab (Avastin) in Patients With Metastatic Colorectal Cancer After Failure Of One First Line Regimen
Official Title: A Randomized, Phase 2 Study Of FOLFOX Or FOLFIRI With AG-013736 Or Bevacizumab (Avastin) In Patients With Metastatic Colorectal Cancer After Failure Of An Irinotecan Or Oxaliplatin-Containing First-Line Regimen
Study ID: NCT00615056
Brief Summary: The study is designed to demonstrate that the combination of AG-013736 with either FOLFIRI or FOLFOX is superior to FOLFIRI or FOLFOX in combination with bevacizumab (Avastin) in delaying tumor progression in the second-line treatment of patients with metastatic colorectal cancer after failure of an irinotecan or oxaliplatin-containing first-line regimen.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Pfizer Investigational Site, Mobile, Alabama, United States
Pfizer Investigational Site, Antioch, California, United States
Pfizer Investigational Site, Los Angeles, California, United States
Pfizer Investigational Site, Los Angeles, California, United States
Pfizer Investigational Site, Pleasant Hill, California, United States
Pfizer Investigational Site, San Leandro, California, United States
Pfizer Investigational Site, Santa Monica, California, United States
Pfizer Investigational Site, Aurora, Colorado, United States
Pfizer Investigational Site, Bonita Springs, Florida, United States
Pfizer Investigational Site, Bradenton, Florida, United States
Pfizer Investigational Site, Cape Coral, Florida, United States
Pfizer Investigational Site, Cape Coral, Florida, United States
Pfizer Investigational Site, Englewood, Florida, United States
Pfizer Investigational Site, Fort Myers, Florida, United States
Pfizer Investigational Site, Fort Myers, Florida, United States
Pfizer Investigational Site, Fort Myers, Florida, United States
Pfizer Investigational Site, Fort Myers, Florida, United States
Pfizer Investigational Site, Naples, Florida, United States
Pfizer Investigational Site, Naples, Florida, United States
Pfizer Investigational Site, Port Charlotte, Florida, United States
Pfizer Investigational Site, Sarasota, Florida, United States
Pfizer Investigational Site, Sarasota, Florida, United States
Pfizer Investigational Site, Venice, Florida, United States
Pfizer Investigational Site, Venice, Florida, United States
Pfizer Investigational Site, Atlanta, Georgia, United States
Pfizer Investigational Site, Ringgold, Georgia, United States
Pfizer Investigational Site, Dubuque, Iowa, United States
Pfizer Investigational Site, Crestview Hills, Kentucky, United States
Pfizer Investigational Site, Paducah, Kentucky, United States
Pfizer Investigational Site, Paducah, Kentucky, United States
Pfizer Investigational Site, Baltimore, Maryland, United States
Pfizer Investigational Site, New Albany, Mississippi, United States
Pfizer Investigational Site, Cincinnati, Ohio, United States
Pfizer Investigational Site, Cincinnati, Ohio, United States
Pfizer Investigational Site, Cincinnati, Ohio, United States
Pfizer Investigational Site, Cincinnati, Ohio, United States
Pfizer Investigational Site, Cincinnati, Ohio, United States
Pfizer Investigational Site, Cincinnati, Ohio, United States
Pfizer Investigational Site, Fairfield, Ohio, United States
Pfizer Investigational Site, Hamilton, Ohio, United States
Pfizer Investigational Site, Chattanooga, Tennessee, United States
Pfizer Investigational Site, Franklin, Tennessee, United States
Pfizer Investigational Site, Gallatin, Tennessee, United States
Pfizer Investigational Site, Germantown, Tennessee, United States
Pfizer Investigational Site, Hermitage, Tennessee, United States
Pfizer Investigational Site, Hixson, Tennessee, United States
Pfizer Investigational Site, Lebanon, Tennessee, United States
Pfizer Investigational Site, Murfreesboro, Tennessee, United States
Pfizer Investigational Site, Nashville, Tennessee, United States
Pfizer Investigational Site, Nashville, Tennessee, United States
Pfizer Investigational Site, Nashville, Tennessee, United States
Pfizer Investigational Site, Nashville, Tennessee, United States
Pfizer Investigational Site, Nashville, Tennessee, United States
Pfizer Investigational Site, Paris, Tennessee, United States
Pfizer Investigational Site, Smyrna, Tennessee, United States
Pfizer Investigational Site, Union City, Tennessee, United States
Pfizer Investigational Site, Corpus Christi, Texas, United States
Pfizer Investigational Site, Mechanicsville, Virginia, United States
Pfizer Investigational Site, Midlothian, Virginia, United States
Pfizer Investigational Site, Richmond, Virginia, United States
Pfizer Investigational Site, Richmond, Virginia, United States
Pfizer Investigational Site, Greenfield Park, Quebec, Canada
Pfizer Investigational Site, Levis, Quebec, Canada
Pfizer Investigational Site, Montreal, Quebec, Canada
Pfizer Investigational Site, Lille, , France
Pfizer Investigational Site, Montpellier, , France
Pfizer Investigational Site, Paris, , France
Pfizer Investigational Site, Villejuif, , France
Pfizer Investigational Site, Genova, , Italy
Pfizer Investigational Site, Padova, , Italy
Pfizer Investigational Site, Roma, , Italy
Pfizer Investigational Site, Roma, , Italy
Pfizer Investigational Site, Kashiwa, Chiba, Japan
Pfizer Investigational Site, Suntougun, Shizuoka, Japan
Pfizer Investigational Site, Chuo-ku, Tokyo, Japan
Pfizer Investigational Site, Daegu, , Korea, Republic of
Pfizer Investigational Site, Jeollanam-do, , Korea, Republic of
Pfizer Investigational Site, Seoul, , Korea, Republic of
Pfizer Investigational Site, Warszawa, , Poland
Pfizer Investigational Site, Warszawa, , Poland
Pfizer Investigational Site, L'hospitalet de Llobregat, Barcelona, Spain
Pfizer Investigational Site, Sabadell, Barcelona, Spain
Pfizer Investigational Site, Madrid, , Spain
Name: Pfizer CT.gov Call Center
Affiliation: Pfizer
Role: STUDY_DIRECTOR