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Brief Title: Evaluation of Metabolic Activity of Liver Metastases by FDG-PET Scanning
Official Title: Exploratory Study on FDG-PET Scanning in Evaluating the Metabolic Activity of Liver Metastases Before and After Resection of the Primary Tumor in Patients With a Colorectal Malignancy
Study ID: NCT00184782
Brief Summary: The purpose of this study is to evaluate the effect of primary tumor resection on the metabolic activity of metastases in patients with a colorectal primary tumor and synchronous liver metastases by positron emission tomography (PET) with 2-deoxy-2-fluoro\[18F\]-D-glucose (FDG-PET) scanning.
Detailed Description: The goal of this study is to evaluate the activity of liver metastases before and after resection of the primary tumor. Non-invasive assessment of tumor metabolism is possible in vivo by means of positron emission tomography (PET)-scanning. Therefore, FDG-PET scan offers a suitable approach to determine the influence of removal of a primary colorectal tumor on metabolic activity of the liver metastases. The FDG uptake in the liver metastases is quantified by calculating standardised uptake values (SUVs).
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Radboud University Nijmegen Medical Centre, Nijmegen, Gelderland, Netherlands
Name: Theo Ruers, PhD
Affiliation: Radboud University Medical Center
Role: PRINCIPAL_INVESTIGATOR