Spots Global Cancer Trial Database for Fluorescence Laparoscopic Navigation for Rectal Cancer and Sigmoid Colon Cancer
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Trial Identification
Brief Title: Fluorescence Laparoscopic Navigation for Rectal Cancer and Sigmoid Colon Cancer
Official Title: A Randomized Controlled Trial of Fluorescence Laparoscopic Navigation of the Extent of Lymph Node Dissection for High Rectal Cancer and Sigmoid Colon Cancer
Study ID: NCT05730595
Interventions
Study Description
Brief Summary: To explore the short-term and long-term outcomes of fluorescence laparoscopic navigation D2 lymph node dissection for colorectal cancer surgery by comparing it with D3 lymph node dissection.
Detailed Description: Lymph node metastasis is the most common metastatic mechanisms for colorectal cancer. Therefore, regional lymph node dissection is the key part in radical surgery for colorectal cancer. In patients who have developed lymph node metastases, inadequate lymph node dissection will promote tumor recurrence. In patients who do not develop lymph node metastases, excessive lymph node dissection not only does not improve the patient's prognosis, but also increases surgical trauma and destroys the antitumor effect of the lymphoid immune system. There is still some controversy over whether to choose D3 lymph node dissection or D2 lymph node dissection for rectal and sigmoid cancer. Fluorescence laparoscopic navigation techniques can guide lymph node dissection by visualizing lymph nodes more clearly during surgery. This study will compare the short-term and long-term oncological outcomes between fluorescence laparoscopic navigation D2 and D3 lymph node dissection by conducting a randomized controlled trial.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui, China
Cancer Hospital Chinese Academy of Medical Sciences, Beijing, Beijing, China
The First Affiliated Hospital of Chengdu Medical College, Chengdu, Chengdu, China
Fujian Province Tumor Hospital, Fuzhou, Fujian, China
Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, Guangdong, China
Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China
Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong, China
Hebei Medical University Fourth Hospital, Shijiazhuang, Hebei, China
The Second Affiliated Hospital of Harbin Medical University, Haerbin, Heilongjiang, China
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China
Jiangxi Provincial Cancer Hospital, Nanchang, Jiangxi, China
The First Hospital of Jilin University, Changchun, Jilin, China
Shengjing Hospital, Shenyang, Liaoning, China
Qinghai University Affiliated Hospital, Xining, Qinghai, China
Binzhou Medical University, Binzhou, Shandong, China
Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China
Shanxi Cancer Hospital, Taiyuan, Shanxi, China
The Second People's Hospital of Yibin, Yibin, Sichuan, China
The second People's Hospital of Yunnan Province, Kunming, Yunnan, China
Contact Details
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