Spots Global Cancer Trial Database for Randomized Study Of Sunitinib Plus FOLFOX Versus Bevacizumab Plus FOLFOX In Metastatic Colorectal Cancer
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Trial Identification
Brief Title: Randomized Study Of Sunitinib Plus FOLFOX Versus Bevacizumab Plus FOLFOX In Metastatic Colorectal Cancer
Official Title: A Randomized, Phase 2B Study Of Sunitinib Plus Oxaliplatin, 5-Fluorouracil And Leucovorin (FOLFOX) Versus Bevacizumab Plus FOLFOX As First-Line Treatment In Patients With Metastatic Colorectal Cancer
Study ID: NCT00609622
Conditions
Study Description
Brief Summary: This study will compare the safety and efficacy of sunitinib in combination with FOLFOX versus bevacizumab in combination with FOLFOX for the treatment of patients with metastatic colorectal cancer who have not been treated before.
Detailed Description: The study was terminated on April 26, 2010 due to lack of efficacy, as determined during the interim analysis of data in April 2010, showing that the study did not meet its primary endpoint to demonstrate a statistically significant improvement in PFS. The decision to terminate the trial was not based on any safety concerns.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Pfizer Investigational Site, Fairhope, Alabama, United States
Pfizer Investigational Site, Mobile, Alabama, United States
Pfizer Investigational Site, Chandler, Arizona, United States
Pfizer Investigational Site, Mesa, Arizona, United States
Pfizer Investigational Site, Bentonville, Arkansas, United States
Pfizer Investigational Site, Fayetteville, Arkansas, United States
Pfizer Investigational Site, Hot Springs, Arkansas, United States
Pfizer Investigational Site, Bakersfield, California, United States
Pfizer Investigational Site, Fresno, California, United States
Pfizer Investigational Site, Fullerton, California, United States
Pfizer Investigational Site, Lancaster, California, United States
Pfizer Investigational Site, Los Angeles, California, United States
Pfizer Investigational Site, Los Angeles, California, United States
Pfizer Investigational Site, Los Angeles, California, United States
Pfizer Investigational Site, Mission Hills, California, United States
Pfizer Investigational Site, Northrige, California, United States
Pfizer Investigational Site, Oxnard, California, United States
Pfizer Investigational Site, Pasadena, California, United States
Pfizer Investigational Site, Redondo Beach, California, United States
Pfizer Investigational Site, Santa Barbara, California, United States
Pfizer Investigational Site, Santa Maria, California, United States
Pfizer Investigational Site, Santa Monica, California, United States
Pfizer Investigational Site, Solvang, California, United States
Pfizer Investigational Site, Valencia, California, United States
Pfizer Investigational Site, Aurora, Colorado, United States
Pfizer Investigational Site, Washington, District of Columbia, United States
Pfizer Investigational Site, Gainesville, Florida, United States
Pfizer Investigational Site, Jacksonville Beach, Florida, United States
Pfizer Investigational Site, Jacksonville, Florida, United States
Pfizer Investigational Site, Jacksonville, Florida, United States
Pfizer Investigational Site, Jacksonville, Florida, United States
Pfizer Investigational Site, Jasonville, Florida, United States
Pfizer Investigational Site, Orange Park, Florida, United States
Pfizer Investigational Site, Palatka, Florida, United States
Pfizer Investigational Site, St. Augustine, Florida, United States
Pfizer Investigational Site, Stuart, Florida, United States
Pfizer Investigational Site, Atlanta, Georgia, United States
Pfizer Investigational Site, Decatur, Georgia, United States
Pfizer Investigational Site, Macon, Georgia, United States
Pfizer Investigational Site, Marietta, Georgia, United States
Pfizer Investigational Site, Sandy Springs, Georgia, United States
Pfizer Investigational Site, Maryville, Illinois, United States
Pfizer Investigational Site, Chanute, Kansas, United States
Pfizer Investigational Site, Dodge City, Kansas, United States
Pfizer Investigational Site, El Dorado, Kansas, United States
Pfizer Investigational Site, Independence, Kansas, United States
Pfizer Investigational Site, Kingman, Kansas, United States
Pfizer Investigational Site, Liberal, Kansas, United States
Pfizer Investigational Site, Newton, Kansas, United States
Pfizer Investigational Site, Parsons, Kansas, United States
Pfizer Investigational Site, Salina, Kansas, United States
Pfizer Investigational Site, Wellington, Kansas, United States
Pfizer Investigational Site, Wichita, Kansas, United States
Pfizer Investigational Site, Wichita, Kansas, United States
Pfizer Investigational Site, Winfield, Kansas, United States
Pfizer Investigational Site, Baltimore, Maryland, United States
Pfizer Investigational Site, Baltimore, Maryland, United States
Pfizer Investigational Site, Columbus, Mississippi, United States
Pfizer Investigational Site, Corinth, Mississippi, United States
Pfizer Investigational Site, Tupelo, Mississippi, United States
Pfizer Investigational Site, Columbia, Missouri, United States
Pfizer Investigational Site, Henderson, Nevada, United States
Pfizer Investigational Site, Las Vegas, Nevada, United States
Pfizer Investigational Site, Las Vegas, Nevada, United States
Pfizer Investigational Site, Las Vegas, Nevada, United States
Pfizer Investigational Site, Norman, Oklahoma, United States
Pfizer Investigational Site, Oklahoma City, Oklahoma, United States
Pfizer Investigational Site, Oklahoma City, Oklahoma, United States
Pfizer Investigational Site, Oklahoma City, Oklahoma, United States
Pfizer Investigational Site, Tulsa, Oklahoma, United States
Pfizer Investigational Site, Tulsa, Oklahoma, United States
Pfizer Investigational Site, Tulsa, Oklahoma, United States
Pfizer Investigational Site, Portland, Oregon, United States
Pfizer Investigational Site, Meadowbrook, Pennsylvania, United States
Pfizer Investigational Site, Philadelphia, Pennsylvania, United States
Pfizer Investigational Site, Philadelphia, Pennsylvania, United States
Pfizer Investigational Site, Radnor, Pennsylvania, United States
Pfizer Investigational Site, Willow Grove, Pennsylvania, United States
Pfizer Investigational Site, Beaumont, Texas, United States
Pfizer Investigational Site, Lubbock, Texas, United States
Pfizer Investigational Site, Wenatchee, Washington, United States
Pfizer Investigational Site, Aalborg, , Denmark
Pfizer Investigational Site, Herlev, , Denmark
Pfizer Investigational Site, Koebenhavn OE, , Denmark
Pfizer Investigational Site, Aschaffenburg, , Germany
Pfizer Investigational Site, Bad Saarow, , Germany
Pfizer Investigational Site, Berlin, , Germany
Pfizer Investigational Site, Duesseldorf, , Germany
Pfizer Investigational Site, Magdeburg, , Germany
Pfizer Investigational Site, Mainz, , Germany
Pfizer Investigational Site, Regensburg, , Germany
Pfizer Investigational Site, Kashiwa, Chiba, Japan
Pfizer Investigational Site, Sapporo, Hokkaido, Japan
Pfizer Investigational Site, Kitaadachi-gun, Ina-cho, Saitama, Japan
Pfizer Investigational Site, Suntougun, Shizuoka, Japan
Pfizer Investigational Site, Utsunomiya, Tochigi, Japan
Pfizer Investigational Site, Chuo-ku, Tokyo, Japan
Contact Details
Name: Pfizer CT.gov Call Center
Affiliation: Pfizer
Role: STUDY_DIRECTOR
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