Spots Global Cancer Trial Database for Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Metastatic Colorectal Cancer.
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Trial Identification
Brief Title: Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Metastatic Colorectal Cancer.
Official Title: A Randomized, Double-blind, Placebo-controlled, Phase Lll Study in Patients With Metastatic Adenocarcinoma of the Colon or Rectum Who Are Receiving First-line Chemotherapy With Oxaliplatin/5-fluorouracil/Leucovorin With PTK787/ZK 222584 or Placebo
Study ID: NCT00056459
Interventions
Study Description
Brief Summary: To compare treatment with oxaliplatin/5-FU/leucovorin plus vatalanib versus oxaliplatin/5-FU/leucovorin plus placebo in patients with colorectal cancer that has spread to other organs and are seeking first chemotherapy treatment
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Alabama Hematology/Oncology, Birmingham, Alabama, United States
Palo Verde Hematology & Oncology, Glendale, Arizona, United States
Arizona Cancer Center, Tucson, Arizona, United States
Northeast Arkansas Clinic, Jonesboro, Arkansas, United States
Highlands Oncology Group, Springdale, Arkansas, United States
Comprehensive Blood and Cancer Center, Bakersfield, California, United States
Providence St. Joseph Medical Center, Burbank, California, United States
Compassionate Cancer Care Medical Group, Inc, Fountain Valley, California, United States
California Oncology of the Central Valley, Fresno, California, United States
Virginia K. Crosson Cancer Center, Fullerton, California, United States
Ronald Yanagiharaa, M.D., Gilroy, California, United States
Glendale Adventist Medical Center Cancer Center, Glendale, California, United States
Pacific Shores Medical Group, Long Beach, California, United States
Cancer Institute Medical Group, Los Angeles, California, United States
USC/Norris Comprehensive Cancer Care Center, Los Angeles, California, United States
Synergy Hematology-Oncology Medical Associates, Los Angeles, California, United States
UCLA School of Medicine, Los Angeles, California, United States
Eddie Hong-Lung Hu, M.D., Monterey Park, California, United States
North Valley Hematology/Oncology Medical Group, Northridge, California, United States
Ventura County Hematology-Oncology Specialists, Oxnard, California, United States
Wilshire Oncology Medical Group, Pomona, California, United States
Sierra View District Hospital, Porterville, California, United States
The Lucy Curci Cancer Center, Rancho Mirage, California, United States
Cancer Care Associates Medical Group, Inc., Redondo Beach, California, United States
Pacific Hematology Oncology Associates, San Francisco, California, United States
Santa Clara Valley Medical Center, San Jose, California, United States
Sansum Santa Barbara Foundation Medical Clinic, Santa Barbara, California, United States
Santa Barbara Hematology Oncology Medical Group, Inc., Santa Barbara, California, United States
San Diego Cancer Center Medical Group, Vista, California, United States
Colorado Cancer Research Program, Denver, Colorado, United States
Jennifer Caskey, M.D., Wheat Ridge, Colorado, United States
Davis, Posteraro and Wasser, MD's, LLP, Manchester, Connecticut, United States
Connecticut Oncology Group, Middletown, Connecticut, United States
Medical Oncology Hematology Consultants, Newark, Delaware, United States
Washington Oncology-Hematology Center, Washington, District of Columbia, United States
George Washington University Medical Center, Washington, District of Columbia, United States
Boca Raton Comprehensive Cancer Center, Boca Raton, Florida, United States
Florida Cancer Specialists, Fort Myers, Florida, United States
Memorial Healthcare System, Hollywood, Florida, United States
Florida Oncology Associates, Jacksonville, Florida, United States
Lakeland Regional Cancer Center, Lakeland, Florida, United States
Innovative Medical Research of South Florida, Miami Shores, Florida, United States
Oncology Hematology Group of South Florida, Miami, Florida, United States
Hematology Oncology Associates of Treasure, Port Saint Lucie, Florida, United States
Florida Medical Clinic, PA, Zephyrhills, Florida, United States
Peachtree Hematology and Oncology, Atlanta, Georgia, United States
Coastal Hematology & Oncology, Savannah, Georgia, United States
North Idaho Cancer Center, Coeur d'Alene, Idaho, United States
Shelby D. Rifkin, M.D., Arlington Heights, Illinois, United States
Monroe Medical Associates, Harvey, Illinois, United States
Oncology Hematology Associates of Central Illinois, PC, Peoria, Illinois, United States
Northshore Cancer Research Association, Skokie, Illinois, United States
Midwest Cancer Research Group, Skokie, Illinois, United States
Hematology-Oncology of Indiana, PC, Indianapolis, Indiana, United States
Associated Physicians & Surgeons Clinic, L.L.C., Terre Haute, Indiana, United States
Markey Clinical Oncology Research Program, Lexington, Kentucky, United States
Norton Healthcare Pavilion, Louisville, Kentucky, United States
Vijay Raghavan, M.D., Louisville, Kentucky, United States
Louisiana Oncology Associates, Lafayette, Louisiana, United States
LSU Medical Center, New Orleans, Louisiana, United States
Tulane University Health Sciences Center, New Orleans, Louisiana, United States
LSU Health Sciences Center, Shreveport, Louisiana, United States
Maine Center for Cancer Medicine & Blood Disorders, Scarborough, Maine, United States
St. Agnes Healthcare, Inc., Baltimore, Maryland, United States
Kaiser Permanente, Rockville, Maryland, United States
St. Joseph Mercy Hospital, Ann Arbor, Michigan, United States
Josephine Ford Cancer Center, Detroit, Michigan, United States
Genesys Hurley Cancer Institute, Flint, Michigan, United States
Spectrum Health -- Cook Research Dept., Grand Rapids, Michigan, United States
Hematology and Oncology Assoc. of Southern Mississippi, Jackson, Michigan, United States
Oncology Care Associates, PLLC, Saint Joseph, Michigan, United States
Providence Cancer Center, Southfield, Michigan, United States
SMDC Health System, Duluth, Minnesota, United States
Minnesota CGOP, Minneapolis, Minnesota, United States
University of Minnesota Cancer Center, Minneapolis, Minnesota, United States
Metro Minnesota CCOP, Saint Louis Park, Minnesota, United States
Heartland Hematology/Oncology Associates, Inc., Kansas City, Missouri, United States
Kansas City Oncology and Hematology Group, Kansas City, Missouri, United States
Missouri Cancer Care, PC, Saint Charles, Missouri, United States
Saint Louis University, Saint Louis, Missouri, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Missouri Baptist Cancer Center, Saint Louis, Missouri, United States
Arch Medical Services Incorporated, Saint Louis, Missouri, United States
North Central Montana Professional Building, Great Falls, Montana, United States
Montana Cancer Specialists, Missoula, Montana, United States
The Methodist Cancer Center, Omaha, Nebraska, United States
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States
Nevada Cancer Center, Las Vegas, Nevada, United States
The Center for Cancer and Hematologic Disease, Cherry Hill, New Jersey, United States
St. Barnabas Cancer Center, Livingston, New Jersey, United States
Hematology-Oncology Associates of New Jersey, Morristown, New Jersey, United States
Southern Oncology and Hematology Associates, Vineland, New Jersey, United States
Cooper Cancer Institute, Voorhees, New Jersey, United States
New Mexico Cancer Care, Santa Fe, New Mexico, United States
Roswell Park Cancer Institute, Buffalo, New York, United States
CR Wood Cancer Center, Glens Falls, New York, United States
Cancer Research of Long Island, Great Neck, New York, United States
Broome Oncology, Johnson City, New York, United States
New York Oncology Hematology, Latham, New York, United States
North Shore University Hospital, Manhasset, New York, United States
Cancer Center at Nyack Hospital, Nyack, New York, United States
Pluta Cancer Center, Rochester, New York, United States
Carolina Medical Center, Charlotte, North Carolina, United States
Mid-Dakota Clinic PC, Bismarck, North Dakota, United States
Nashat Gabrail, M.D., Canton, Ohio, United States
Mid Ohio Oncology/Hematology, Inc., Columbus, Ohio, United States
Hematology Oncology Consultants, Inc., Columbus, Ohio, United States
Meridia Cancer Institute, Mayfield Heights, Ohio, United States
Cancer Care Associates, Oklahoma City, Oklahoma, United States
Cancer Care Associates, Tulsa, Oklahoma, United States
Kaiser Permanente Oncology Hematology, Portland, Oregon, United States
Hershey Medical Center, Hershey, Pennsylvania, United States
Monogahela Valley Hospital, Monongahela, Pennsylvania, United States
University of Pennsylvania Abramson Cancer Center, Philadelphia, Pennsylvania, United States
Allegheny Cancer Center, Pittsburgh, Pennsylvania, United States
Charleston Hematology Oncology, Charleston, South Carolina, United States
Charleston Cancer Center, Charleston, South Carolina, United States
South Carolina Oncology Associates, Columbia, South Carolina, United States
Cancer Center of the Carolinas, Greenville, South Carolina, United States
Spartanburg Regional Medical Center, Spartanburg, South Carolina, United States
The Jones Clinic, Germantown, Tennessee, United States
Baptist Regional Cancer Center, Knoxville, Tennessee, United States
University of Tennessee Cancer Institute, Memphis, Tennessee, United States
Sarah Cannon Cancer Center, Nashville, Tennessee, United States
Southwest Regional Cancer Center, Austin, Texas, United States
Corpus Christi Cancer Center, Corpus Christi, Texas, United States
Center for Oncology Research & Treatment, PA, Dallas, Texas, United States
Oncology Consultants, Houston, Texas, United States
H. Alejandro Preti, MD, PA, Houston, Texas, United States
M.D. Anderson Cancer Center, Houston, Texas, United States
Dr. Lee C. Drinkard, Irving, Texas, United States
Scott & White Hospital, Temple, Texas, United States
North Utah Associates, Ogden, Utah, United States
Utah Cancer Specialists, Salt Lake City, Utah, United States
Southwestern Vermont Health Care, Bennington, Vermont, United States
Danville Hematology and Oncology, Inc., Danville, Virginia, United States
Northern Virginia Oncology Group, Fairfax, Virginia, United States
Virginia Oncology Associates, Norfolk, Virginia, United States
Cancer Treatment Centers of America, Portsmouth, Virginia, United States
Virginia Cancer Institute, Richmond, Virginia, United States
Western Washington Medical Group, Everett, Washington, United States
Western Washington Medical Group, Everett, Washington, United States
Cascade Cancer Center, Kirkland, Washington, United States
UW Health -- University of Wisconsin Comp, Madison, Wisconsin, United States
Waukesha Memorial Hospital, Waukesha, Wisconsin, United States
, Adelaide, , Australia
, Garran, , Australia
, Nedlands, , Australia
, Wollongong, , Australia
, Woolloongabba, , Australia
, Anderlecht, , Belgium
, Antwerpen, , Belgium
, Bruxelles, , Belgium
, Gent, , Belgium
, Wilrijk, , Belgium
, Porto Alegre RS, , Brazil
, Porto Alegre, , Brazil
, Salvador, , Brazil
, Sao Paulo, , Brazil
, Sao Paulo, , Brazil
, Sao Paulo, , Brazil
, Hamilton, Ontario, Canada
Novartis Investigative Site, Toronto, Ontario, Canada
, Toronto, Ontario, Canada
, Sainte-Foy, Quebec, Canada
, Brno, , Czechia
, Praha 2, , Czechia
, Praha 5, , Czechia
, Marseille cedex 05, , France
, Marseille Cedex 9, , France
, Strasbourg, , France
, Augsburg, , Germany
, Berlin, , Germany
, Berlin, , Germany
, Dessau, , Germany
, Erlangen, , Germany
, Eschweiler, , Germany
, Essen, , Germany
, Frankfurt, , Germany
, Hannover, , Germany
, Heidelberg, , Germany
, Kiel, , Germany
, Köln, , Germany
, Leipzig, , Germany
, Magdeburg, , Germany
, Budapest, , Hungary
, Budapest, , Hungary
, Gyor, , Hungary
, Szeged, , Hungary
, Forli, , Italy
, Genova, , Italy
, Milano, , Italy
, Modena, , Italy
, Roma, , Italy
, Roma, , Italy
, Rozzano, , Italy
, Torino, , Italy
, GA Utrecht, , Netherlands
Novartis Investigative Site, Hamilton, , New Zealand
, Palmerston North, , New Zealand
, Coimbra, , Portugal
Novartis Investigative Site, Bratislava, , Slovakia
Novartis Investigative Site, Bratislava, , Slovakia
Novartis Investigative Site, Kosice, , Slovakia
Novartis Investigative Site, Zilina, , Slovakia
, Alicante, , Spain
, Madrid, , Spain
, Madrid, , Spain
, Madrid, , Spain
, Malaga, , Spain
, Zaragoza, , Spain
, Stockholm, , Sweden
, Basel, , Switzerland
, Bern, , Switzerland
, Thun, , Switzerland
, Zurich, , Switzerland
, Zürich, , Switzerland
, Tainan, , Taiwan
, Taipei, , Taiwan
, Tao-Yuan, , Taiwan
, Belfast, , United Kingdom
, Leicester, , United Kingdom
, Oxford, , United Kingdom
Contact Details
Name: Novartis / Schering AG, Germany
Affiliation: Novartis / Schering AG, Germany
Role: STUDY_CHAIR
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