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Brief Title: Radiotherapy in Combination With Sintilimab,GM-CSF and Fruquintinib in Patients With MSS mCRC
Official Title: A Trial of Hypofractionation Radiotherapy in Combination With Sintilimab,GM-CSF and Fruquintinib in Patients With MSS Metastatic Colorectal Carcinoma (mCRC)
Study ID: NCT05292417
Brief Summary: To evaluate the clinical efficacy and safety of hypofractionation radiotherapy combined with sintilimab,GM-CSF and Fruquintinib in Patients With MSS Metastatic Colorectal Carcinoma (mCRC)
Detailed Description: Condition or disease:MSS Metastatic Colorectal Carcinoma (mCRC) Phase:Phase 2 Intervention/treatment: Radiation: hypofractionation radiotherapy Drug: sintilimab, GM-CSF , Fruquintinib
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China
Name: Mingquan Cai
Affiliation: The First Affiliated Hospital of Xiamen University
Role: PRINCIPAL_INVESTIGATOR
Name: Xiyi Liao
Affiliation: The First Affiliated Hospital of Xiamen University
Role: PRINCIPAL_INVESTIGATOR