Spots Global Cancer Trial Database for Effect of Peritoneal Lavage With Clindamycin-Gentamicin Solution & Oncologic Outcome
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Trial Identification
Brief Title: Effect of Peritoneal Lavage With Clindamycin-Gentamicin Solution & Oncologic Outcome
Official Title: Effect of Peritoneal Lavage With Clindamycin-Gentamicin Solution During Elective Colorectal Cancer Surgery on the Oncologic Outcome
Study ID: NCT02399059
Conditions
Study Description
Brief Summary: Antibiotic lavage reduces bacterial contamination and decreases SSI infection rate. SSI leads to an immunocompromised situation, leaving unattended the neoplasm. It has been described that SSI may result in a worse oncologic outcome.
Detailed Description: Antibiotics combined with lavage have demonstrated a reduction in the bacterial contamination and decreases SSI infection rate. SSI leads to an immunocompromised situation, as immunologic defense is focused on controlling the septic focus, leaving unattended the neoplasm. It has been described that SSI may result in a worse oncologic outcome. The aim of this study is to evaluate prospectively the effect of peritoneal lavage with clindamycin and gentamicin on the oncologic outcome of colorectal tumours.
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Contact Details
Name: Jaime Ruiz-Tovar, MD, PhD
Affiliation: Hospital Rey Juan Carlos
Role: PRINCIPAL_INVESTIGATOR
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