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Spots Global Cancer Trial Database for COVID-19 Infection in Cancer Pantients

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: COVID-19 Infection in Cancer Pantients

Official Title: Clinical Course of Cancer Patients Who Contracted COVID 19 Infection: An Observational Study

Study ID: NCT04569292

Conditions

Covid19

Study Description

Brief Summary: It's an obsevational retrospective/prospective study. Analyzing the evolution of COVID 19 infection in cancer patients can provide interesting information in the management of these patients. For this reason, the purpose of this study is to implement a registry to describe and monitor cancer patients affected by COVID 19, the factors that are associated with an unfavorable evolution, to develop a strategy for the risk assessment of these patients and recommendations. relating to their treatment. Particular attention will be paid to patients suffering from urological tumors because the treatment followed by the patients would seem to expose them to a greater risk when they are infected with coronavirus, furthermore, from the literature it is clear that there may be a connection between sex hormones and ACE2 levels in the plasma. In fact, the estrons up-regulate the concentration of ACE2 in the circulation and this could be the reason why women would seem more protected than men once they contract the coronavirus infection

Detailed Description: Primary objectives: * describe cancer patients with COVID-19 and their clinical course; * identify predictors of the most severe clinical course; * identify prognostic factors; Secondary objectives * Monitor patients with urological tumors with particular attention; * Dosing parameters of inflammation such as IL-6 and IFNα; * Measure the ACE2 levels. Patients with oncological pathology who contracted COVID 19 infection from January 1, 2020 until the WHO declaration of the end of the pandemic will be studied.

Eligibility

Minimum Age:

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Oncology Unit, Hospital Andrea Tortora, Pagani, Salerno, Italy

Contact Details

Name: Giuseppe Di Lorenzo

Affiliation: Oncology Unit

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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