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Brief Title: Efficacy and Safety of Pasireotide Administered Monthly in Patients With Cushing's Disease
Official Title: A Randomized, Double-blind, Multicenter, Phase III Study to Evaluate the Efficacy and Safety of Pasireotide LAR in Patients With Cushing's Disease
Study ID: NCT01374906
Brief Summary: This is a randomized, double-blind, multicenter, phase III study to evaluate the safety and efficacy of 2 dosing regiments of Pasireotide long acting release (LAR) in patients with Cushing's disease.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
ClinTriCo, Phoenix, Arizona, United States
University of California at Los Angeles UCLA Tiverton, Los Angeles, California, United States
Harbor-UCLA Medical Center LA Biomed, Torrance, California, United States
Emory University School of Medicine/Winship Cancer Institute G2304 - C2301, Atlanta, Georgia, United States
Pituitary Center, Division of Endocrinology SC, Baltimore, Maryland, United States
University of Michigan Comprehensive Cancer Center SC-2, Ann Arbor, Michigan, United States
Mount Sinai School of Medicine Mt. Sinai Medical Center, New York, New York, United States
Oregon Health & Sciences University DeptofOregonHealth&Sciences(2), Portland, Oregon, United States
University of Pennsylvania - Clinical Studies Unit Unniv SC, Philadelphia, Pennsylvania, United States
Vanderbilt University Medical Center CSOM230G2304, Nashville, Tennessee, United States
Swedish Medical Center Swedish, Seattle, Washington, United States
Medical College of Wisconsin MCW 2, Milwaukee, Wisconsin, United States
Novartis Investigative Site, Buenos Aires, , Argentina
Novartis Investigative Site, Cordoba, , Argentina
Novartis Investigative Site, Edegem, Antwerpen, Belgium
Novartis Investigative Site, Jette, Brussel, Belgium
Novartis Investigative Site, Bruxelles, , Belgium
Novartis Investigative Site, Gent, , Belgium
Novartis Investigative Site, Leuven, , Belgium
Novartis Investigative Site, Fortaleza, CE, Brazil
Novartis Investigative Site, Rio de Janeiro, RJ, Brazil
Novartis Investigative Site, Ribeirao Preto, SP, Brazil
Novartis Investigative Site, São Paulo, SP, Brazil
Novartis Investigative Site, Halifax, Nova Scotia, Canada
Novartis Investigative Site, Montreal, Quebec, Canada
Novartis Investigative Site, Sherbrooke, Quebec, Canada
Novartis Investigative Site, Beijing, Beijing, China
Novartis Investigative Site, Chengdu, Sichuan, China
Novartis Investigative Site, Shanghai, , China
Novartis Investigative Site, Shanghai, , China
Novartis Investigative Site, Besancon cedex, , France
Novartis Investigative Site, Caen Cedex9, , France
Novartis Investigative Site, Le Kremlin Bicetre, , France
Novartis Investigative Site, Lille Cedex, , France
Novartis Investigative Site, Marseille Cédex 5, , France
Novartis Investigative Site, Pessac Cedex, , France
Novartis Investigative Site, Berlin, , Germany
Novartis Investigative Site, Erlangen, , Germany
Novartis Investigative Site, Germering, , Germany
Novartis Investigative Site, Wurzburg, , Germany
Novartis Investigative Site, Mumbai, Maharashtra, India
Novartis Investigative Site, Vellore, Tamil Nadu, India
Novartis Investigative Site, New Delhi, , India
Novartis Investigative Site, Petach Tikva, , Israel
Novartis Investigative Site, Ancona, AN, Italy
Novartis Investigative Site, Milano, MI, Italy
Novartis Investigative Site, Milano, MI, Italy
Novartis Investigative Site, Padova, PD, Italy
Novartis Investigative Site, Napoli, , Italy
Novartis Investigative Site, Nagoya, Aichi, Japan
Novartis Investigative Site, Fukuoka city, Fukuoka, Japan
Novartis Investigative Site, Maebashi city, Gunma, Japan
Novartis Investigative Site, Sapporo-city, Hokkaido, Japan
Novartis Investigative Site, Kobe-city, Hyogo, Japan
Novartis Investigative Site, Nankoku-city, Kochi, Japan
Novartis Investigative Site, Kyoto-city, Kyoto, Japan
Novartis Investigative Site, Suita-city, Osaka, Japan
Novartis Investigative Site, Bunkyo-ku, Tokyo, Japan
Novartis Investigative Site, Minato-ku, Tokyo, Japan
Novartis Investigative Site, Shinjuku-ku, Tokyo, Japan
Novartis Investigative Site, Osaka, , Japan
Novartis Investigative Site, Rotterdam, , Netherlands
Novartis Investigative Site, Jesus Maria, Lima, Peru
Novartis Investigative Site, Miraflores, Lima, Peru
Novartis Investigative Site, Gdansk, , Poland
Novartis Investigative Site, Poznan, , Poland
Novartis Investigative Site, Warszawa, , Poland
Novartis Investigative Site, Wroclaw, , Poland
Novartis Investigative Site, Moscow, , Russian Federation
Novartis Investigative Site, St.- Petersburg, , Russian Federation
Novartis Investigative Site, Sevilla, Andalucia, Spain
Novartis Investigative Site, Alzira, Comunidad Valenciana, Spain
Novartis Investigative Site, Barcelona, , Spain
Novartis Investigative Site, Bangkok, , Thailand
Novartis Investigative Site, Bangkok, , Thailand
Novartis Investigative Site, Diskapi / Ankara, Ankara, Turkey
Novartis Investigative Site, Istanbul, TUR, Turkey
Novartis Investigative Site, Izmir, , Turkey
Novartis Investigative Site, Salford, Manchester, United Kingdom
Novartis Investigative Site, Norwich, , United Kingdom
Novartis Investigative Site, Sheffield, , United Kingdom
Novartis Investigative Site, Southampton, , United Kingdom
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmaceuticals
Role: STUDY_DIRECTOR