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Brief Title: A Study to Evaluate INCB099280 in Participants With Advanced Cutaneous Squamous Cell Carcinoma
Official Title: A Phase 2 Study Evaluating INCB099280 in Participants With Advanced Squamous Cell Carcinoma
Study ID: NCT05888844
Brief Summary: This study is being conducted to determine the safety, tolerability, and preliminary efficacy of INCB099280 in participants with advanced Cutaneous Squamous Cell Carcinoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Scripps Green Hospital, La Jolla, California, United States
Valkyrie Clinical Trials, Los Angeles, California, United States
University of Michigan, Ann Arbor, Michigan, United States
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States
Tennessee Oncology Pllc, Nashville, Tennessee, United States
University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States
Border Medical Oncology Research Unit, Albury, New South Wales, Australia
Townsville Cancer Centre, Townsville, Queensland, Australia
Princess Alexandra Hospital Australia, Woolloongabba, Queensland, Australia
Bendigo Hospital, Bendigo, Victoria, Australia
Box Hill Hospital, Box Hill, Victoria, Australia
Monash Medical Centre Clayton, Clayton, Victoria, Australia
Fundacao Pio Xii Hospital de Cancer de Barretos, Barretos, , Brazil
Cepen - Centro de Pesquisa E Ensino Em Oncologia de Santa Catarina, Florianópolis, , Brazil
Oncosite - Centro de Pesquisa Clinica E Oncologia, Ijui, , Brazil
Fundacao Doutor Amaral Carvalho, JAÚ, , Brazil
Hospital Sao Vicente de Paulo, Passo Fundo, , Brazil
Irmandade Da Santa Casa de Misericordia de Porto Alegre, Porto Alegre, , Brazil
Hospital de Clinicas de Porto Alegre, Porto Alegre, , Brazil
Hgb - Hospital Giovanni Battista - Mae de Deus Center, Porto Alegre, , Brazil
Hospital Nossa Senhora Da Conceicao, Porto Alegre, , Brazil
Nob - Nucleo de Oncologia Da Bahia, Salvador, , Brazil
Instituto de Oncologia Saint Gallen, Santa Cruz Do Sul, , Brazil
Cepho - Centro de Estudos E Pesquisas de Hematologia E Oncologia, Santo André, , Brazil
Fundacao Faculdade Regional de Medicina de Sao Jose Do Rio Preto, Sao Jose Do Rio Preto, , Brazil
Instituto Do Cancer de Sao Paulo - Icesp, São Paulo, , Brazil
A. C. Camargo Cancer Center, São Paulo, , Brazil
Q.E. Ii Health Sciences Centre, Halifax, Nova Scotia, Canada
Toronto Sunnybrook Hospital, Toronto, Ontario, Canada
Jewish General Hospital, Montreal, Quebec, Canada
McGill University Jewish General Hospital, Montreal, Quebec, Canada
Cdiem - Centro de Investigacion Y Especialidades Medicas, Santiago, , Chile
Centro de Investigacion Clinica Bradford Hill, Santiago, , Chile
James Lind Centro de Investigacion Del Cancer, Temuco, , Chile
Clinical Research Chile Spa., Valdivia, , Chile
Clinica de La Costa S.A.S, Barranquilla, , Colombia
Administradora Country S.A., Bogota, , Colombia
Instituto Nacional de Cancerologia, Bogota, , Colombia
Oncomedica S.A., Monteria, , Colombia
Specialty Hospital Medico, Rijeka, , Croatia
University Hospital Centre Sestre Milosrdnice, Zagreb, , Croatia
Helsinki University Central Hospital, Helsinki, , Finland
Avicenne Hospital, Bobigny Cedex, , France
Bordeaux Chu Hopital Saint - Andre, Bordeaux, , France
Hospital Ambroise Pare, Boulogne-billancourt, , France
Chu de Clermont - Ferrand- Hospital Estaing, Clermont Ferrand Cedex 1, , France
Centre Georges Francois Leclerc, Dijon Cedex, , France
Chu Dijon - Hôpital François Mitterrand, Dijon, , France
Centre Hospitalier Universitaire Grenoble Alpes (Chu Grenoble Alpes) - Hopital Albert Michallon, La Tronche, , France
Chru de Lille Hopital Claude Huriez, Lille Cedex, , France
Chu Hopital de La Timone, Marseille Cedex 5, , France
Centre Hospitalier Universitaire de Nantes (Chu de Nantes) - Hotel-Dieu, Nantes, , France
Chu de Nice - Hospital L Archet, Nice Cedex 3, , France
Hospital Saint Louis, Paris, , France
Centre Hospitalier de Pau - Hôpital François Mitterrand, Pau Cedex, , France
Hospices Civils de Lyon Centre Hospitalier Lyon Sud, Pierre Bénite Cedex, , France
Hopital Charles Nicolle Chu Rouen Hospital de Bois-Guillaume, Rouen Cedex, , France
University Hospital of Saint Etienne, Saint Etienne Cedex 2, , France
Institut Gustave Roussy, Villejuif Cedex, , France
Semmelweis Egyetem, Budapest, , Hungary
Pecsi Tudomanyegyetem, Pecs, , Hungary
Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont, Szeged, , Hungary
Cha Bundang Medical Center, Seongnam-si,, , Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Severance Hospital Yonsei University Health System, Seoul, , Korea, Republic of
Asan Medical Center, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Centro Estatal de Cancerologia de Chihuahua, Chihuahua, , Mexico
Health Pharma Professional Research S.A. de C.V., Ciudad de México, , Mexico
Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, , Mexico
Preparaciones Oncologicas, S.C, Leon, , Mexico
Merida - Investigacion Clinica, Merida, , Mexico
Centro de Atención E Investigación Clínica En Oncología, Merida, , Mexico
Centro de Investigacion Clinica de Oaxaca, Mexico, , Mexico
Joaquin Gabriel Reinoso Toledo, Monterrey, , Mexico
I Can Oncology Center S.A. de C.V., Monterrey, , Mexico
Instituto Veracruzano En Investigacion Clinica S.C, Veracruz, , Mexico
Clinical Center of Montenegro, Podgorica, , Montenegro
Universitair Medisch Centrum Groningen (Umcg), Groningen, , Netherlands
Waikato Hospital, Hamilton, , New Zealand
University Clinic For Radiotherapy and Oncology, Skopje, , North Macedonia
Spitalul de Oncologie Monza Srl, Bucuresti, , Romania
S.C Policlinica Ccbr S.R.L, Bucuresti, , Romania
Institutul Oncologic Prof. Dr. Ion Chiricuta Cluj-Napoca, Cluj Napoca, , Romania
Medisprof, Cluj-napoca, , Romania
Centrul de Oncologie Sf. Nectarie Craiova, Craiova, , Romania
S.C. Sigmedical Services Srl, Suceava, , Romania
Oncomed Srl, Timisoara, , Romania
Johese Clinical Research: Midstream, Centurion, , South Africa
Chris Hani Baragwanath Hospital, Johannesburg, , South Africa
Wits Clinical Research, Johannesburg, , South Africa
The Medical Oncology Centre of Rosebank, Johannesburg, , South Africa
Phoenix Pharma (Pty) Ltd, Port Elizabeth, , South Africa
University of Pretoria Oncology Department, Pretoria, , South Africa
Germans Trias I Pujol, Badalona, , Spain
Hospital General Universitario Vall D Hebron, Barcelona, , Spain
Hospital Clinic Barcelona Main, Barcelona, , Spain
Hospital de La Santa Creu I Sant Pau, Barcelona, , Spain
Hospital Universitario Virgen de La Arrixaca, El Palmar, , Spain
Ico Institut Catala D Oncologia, L'hospitalet de Llobregat, , Spain
Hospital General Universitario Gregorio Maranon, Madrid, , Spain
Clinical Universidad de Navarra Madrid, Madrid, , Spain
Hospital Universitario Ramon Y Cajal, Madrid, , Spain
Hospital Regional Universitario de Malaga, Málaga, , Spain
Clinica Universidad de Navarra (Cun), Pamplona, , Spain
Hospital Universitario Donostia, San Sebastian, , Spain
Hospital Universitario Virgen Macarena, Sevilla, , Spain
Hospital Universitario Miguel Servet, Zaragoza, , Spain
Medical Park Seyhan Hospital, Adana, , Turkey
Baskent University Adana Application and Research Center, Adana, , Turkey
Ankara City Hospital, Ankara, , Turkey
Trakya University Medical Faculty, Edirne, , Turkey
Istanbul University Cerrahpasa - Cerrahpasa Medical Faculty, Istanbul, , Turkey
Name: Incyte Medical Monitor
Affiliation: Incyte Corporation
Role: STUDY_DIRECTOR