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Spots Global Cancer Trial Database for Study of Oral LBH589 in Adult Participants With Refractory/Resistant Cutaneous T-Cell Lymphoma (CTCL)

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Trial Identification

Brief Title: Study of Oral LBH589 in Adult Participants With Refractory/Resistant Cutaneous T-Cell Lymphoma (CTCL)

Official Title: A Phase II Study of Oral LBH589 in Adult Patients With Cutaneous T-Cell Lymphoma Who Are Intolerant to or Have Progressed on or After Prior HDAC Inhibitor

Study ID: NCT00490776

Interventions

Panobinostat

Study Description

Brief Summary: This study evaluated the safety and efficacy of LBH589B in adult participants with refractory/resistant Cutaneous T-Cell Lymphoma and prior Histone Deacetylase (HDAC) inhibitor therapy.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Alabama at Birmingham/ The Kirklin Clinic, Birmingham, Alabama, United States

UCLA Medical Center School of Medicine/ Dpt of Hematology-Oncology, Los Angeles, California, United States

University of Colorado Health Sciences Center/Anschutz Cancer Pavillion, Aurora, Colorado, United States

Florida Academic Dermatology Centers, Miami, Florida, United States

Medical College of Georgia, Augusta, Georgia, United States

Rush Presbyterian Hospital/St. Luke's Medical Center, Chicago, Illinois, United States

St. Louis University Cancer Cennter, Saint Louis, Missouri, United States

Nebraska Medical Center, Omaha, Nebraska, United States

Our Lady of Mercy Medical Center/Comprehensive Cancer Center, Bronx, New York, United States

Roswell Park Cancer Institute, Buffalo, New York, United States

NYU Clinical Cancer Center, New York, New York, United States

Wake University Health Sciences, Winston-Salem, North Carolina, United States

University of Oklahoma-Tulsa, Tulsa, Oklahoma, United States

Craig Okada, Portland, Oregon, United States

University of Pittsburg Medical Center, Pittsburgh, Pennsylvania, United States

The Jones Clinic, Germantown, Tennessee, United States

MD Anderson Cancer Center/University of Texas, Houston, Texas, United States

Seattle Cancer Care Alliance, Seattle, Washington, United States

Contact Details

Name: Novartis Pharmaceuticals

Affiliation: Novartis Pharmaceuticals

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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