Spots Global Cancer Trial Database for Short-term Perioperative Thromboprophylaxis After Major Abdominal Surgery

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Trial Identification

Brief Title: Short-term Perioperative Thromboprophylaxis After Major Abdominal Surgery

Official Title: Outcomes of Short-term Perioperative Thromboprophylaxis After Gastrointestinal Cancer Surgery

Study ID: NCT04709510

Conditions

Deep Vein Thrombosis

Interventions

Duplex Ultrasound

Study Description

Brief Summary: Major abdominal surgery for cancer is major risk factor for thromboembolism. Patients who undergo major abdominal surgery are prone to develop venous thromboembolism, both in the early postoperative period and after hospital discharger. There are strong recommendations in the international guidelines in favor to pharmacological thromboprophylaxis. Thus there is no consensus dor the duration of the prophylaxis. There are authors that suggest extended prophylaxis up to 4 week after surgery. On the other hand, there are prospective randomized trials that inpatient (short-term up to 7-10 days) prophylaxis is adequate.

Detailed Description: This is a retrospective cohort study with 89 patients who underwent major abdominal surgery for colorectal and gastric cancer. All patients received short term prophylaxis (during hospital stay only) rather than extended prophylaxis (4 weeks). All participants received duplex ultrasound in the study period for the diagnosis of deep vein thrombosis.