Spots Global Cancer Trial Database for CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Desmoplastic Small Round Cell Tumor
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Trial Identification
Brief Title: CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Desmoplastic Small Round Cell Tumor
Official Title: A Randomized, Open-Label Phase 1/2 Study Evaluating Ramucirumab in Pediatric Patients and Young Adults With Relapsed, Recurrent, or Refractory Desmoplastic Small Round Cell Tumor
Study ID: NCT04145349
Conditions
Study Description
Brief Summary: This study is being conducted to test the safety and efficacy of ramucirumab in combination with other chemotherapy in the treatment of relapsed, recurrent, or refractory desmoplastic small round cell tumor (DSRCT) in children and young adults. This trial is part of the CAMPFIRE master protocol (NCT05999994) which is a platform to accelerate the development of new treatments for pediatric and young adult participants with cancer. Your participation in this trial could last 12 months or longer, depending on how you and your tumor respond.
Detailed Description:
Eligibility
Minimum Age: 12 Months
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Phoenix Children's Hospital, Phoenix, Arizona, United States
Childrens Hospital of Los Angeles, Los Angeles, California, United States
Children's National Medical Center, Washington, District of Columbia, United States
Washington University, Saint Louis, Missouri, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Oregon Health and Science University, Portland, Oregon, United States
Children's Hospital of Philadelphia (CHOP), Philadelphia, Pennsylvania, United States
Royal Children's Hospital, Parkville, Victoria, Australia
Universitaetsklinikum Freiburg, Freiburg, Baden-Württemberg, Germany
Universitaetsklinikum Essen, Essen, Nordrhein-Westfalen, Germany
Universitaetsklinikum Hamburg-Eppendorf, Hamburg, , Germany
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Lombardia, Italy
Humanitas, Rozzano, Milano, Italy
Ospedale Pediatrico Bambino Gesù, Rome, Roma, Italy
Azienda Ospedaliera di Padova, Padova, Veneto, Italy
Kyushu University Hospital, Fukuoka, , Japan
Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona], Spain
Hospital Universitario Virgen Del Rocio, Sevilla, , Spain
University College London Hospital, London, London, City Of, United Kingdom
Royal Marsden Hospital (Sutton), London, Sutton, United Kingdom
Royal Manchester Children's Hospital, Manchester, , United Kingdom
The Christie NHS Foundation Trust, Manchester, , United Kingdom
Contact Details
Name: Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)
Affiliation: Eli Lilly and Company
Role: STUDY_DIRECTOR
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