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Brief Title: Dexmedetomidine Alleviates Postoperative Delirium After Brain Tumor Resections
Official Title: Effect of Dexmedetomidine on Postoperative Delirium in Patients Undergoing Brain Tumor Resections: a Randomized Controlled Study
Study ID: NCT04674241
Brief Summary: Postoperative delirium (POD) is a common complication, and the incidence rate is about 25% in non cardiac surgery. Previous studies have reported that the total incidence of neurological pod ranged from 10% to 22%. Dexmedetomidine (DEX) is an a-2 adrenergic agonist for sedation. This kind of drug has little effect on respiratory function, is easy to wake up and has analgesic effect. It is a commonly used perioperative adjuvant drug. However, for neurosurgical patients with brain tumors, the role of DEX in POD is not clear. The purpose of this study was to investigate the effect of DEX on POD in neurosurgical brain tumor surgery.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Beijing TianTan Hospital,Capital Medical University, Beijing, Beijing,China, China
PLA General Hospital, Beijing, , China
Name: Yu Ming Peng, MD,Ph.D
Affiliation: Beijing Tian Tan Hospital
Role: PRINCIPAL_INVESTIGATOR