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Brief Title: Anti-TNFα to Delay or Prevent Progression to Stage 3 T1D
Official Title: Tumor Necrosis Factor Blocker (Anti-TNFα) to Delay or Prevent Progression to Stage 3 T1D
Study ID: NCT04729296
Brief Summary: This will be a study conducted as a placebo-controlled, double blind, 1:1 randomized controlled clinical trial testing a Tumor Necrosis Factor Blocker (Anti-TNFα) substance versus placebo in subjects with a 2-year 50% risk of progression to stage 3 T1D across multiple centers. The trial will investigate the ability of Anti-TNFα to prevent or delay progression to Stage 3 T1D in the targeted patient population.
Detailed Description:
Minimum Age: 3 Years
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Name: Carla Greenbaum, MD
Affiliation: Type 1 Diabetes TrialNet
Role: STUDY_CHAIR