Spots Global Cancer Trial Database for Initial Management in Patients With Differentiated Thyroid Cancer in the Real World in China

Study Description

Brief Summary: * To find out the gap between real-world clinical practice and guideline recommendations in initial management of DTC patients * To observe the characteristics of patients who achieved and did not achieve TSH target value after one year follow-up * To assess response to initial therapy in patients who undergo total or near-total thyroidectomy and RAI remnant ablation after one year follow-up (according to an modified dynamic risk stratification system) * To observe the recurrence status after one year follow-up

Detailed Description: Multi-center, prospective, registry study 2000 DTC patients undergo the first-time thyroidectomy and identified as intermediate or high risk of recurrence will be recruited. Doctors can treat the patients based on disease conditions. Investigators will record data which are related to study endpoints. Primary endpoint(s): 1. Proportion of patients who underwent total/near-total thyroidectomy 2. Proportion of patients who were treated by 131I after undergoing total/near-total thyroidectomy 3. Proportion of patients who achieved serum TSH target value 4. Proportion of patients who did not achieve serum TSH target value although they were treated by TSH suppression therapy Secondary endpoint(s): 1. Time to achieve serum TSH target value 2. Dosage of L-T4 for patients who achieved and did not achieve serum TSH target value 3. Dosage of L-T4 per kilogram of body weight for patients who achieved and did not achieve serum TSH target value 4. Proportion of excellent response/Acceptable response/Biochemical incomplete response/Structural incomplete response to initial management in patients who undergo total or near-total thyroidectomy and RAI remnant ablation after one year follow-up 5. Recurrence rate after one year follow-up 6. AEs related to L-T4 (or thyroid tablet)treatment

Keywords

Eligibility

Minimum Age:

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Contact Details

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