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Brief Title: Phase 2 Trial of Donafenib in 131I-Refractory Differentiated Thyroid Cancer
Official Title: A Multicenter, Randomized, Open-Label,Phase 2 Trial of Donafenib in 131I-Refractory Differentiated Thyroid Cancer
Study ID: NCT02870569
Brief Summary: Donafenib for advanced 131I-refractory/resistant differentiated thyroid cancer(DTC).
Detailed Description: This phase 2 study of donafenib, an oral multikinase inhibitor that targets Raf kinase and receptor tyrosine kinases, is to assess efficacy and safety in patients with 131I-refractory/resistant differentiated thyroid cancer.The study is a randomised,multicentre,open-label study.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Peking Union Medical College Hospital, Beijing, Beijing, China