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Spots Global Cancer Trial Database for A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

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Trial Identification

Brief Title: A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

Official Title: A Phase 3, Randomized, Open-Label Study to Evaluate Safety and Efficacy of Epcoritamab in Combination With R-CHOP Compared to R-CHOP in Subjects With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

Study ID: NCT05578976

Study Description

Brief Summary: B-cell Lymphoma is an aggressive and rare cancer of a type of immune cells (a white blood cell responsible for fighting infections). The purpose of this study is to assess the change in disease activity of epcoritamab when combined with intravenous and oral rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine, and prednisone (R-CHOP) or R-CHOP in adult participants globally with diffuse large b-cell lymphoma (DLBCL). Change in disease activity will be assessed. Epcoritamab is an investigational drug being developed for the treatment of DLBCL. Study doctors put the participants in groups called treatment arms. Participants will receive epcoritamab combined with R-CHOP, followed by epcoritamab or R-CHOP followed by rituximab will be explored. Approximately 900 adult participants with with newly diagnosed DLBCL will be enrolled in the study in approximately 315 sites in globally. In the Arm 1, participants will receive subcutaneous epcoritamab combined with intravenous and oral R-CHOP followed by subcutaneous epcoritamab in 21-day cycles. In the Arm 2, participants will receive intravenous and oral R-CHOP followed by intravenous rituximab in 21-day cycles. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at an approved institution (hospital or clinic). The effect of the treatment will be frequently checked by medical assessments, blood tests, questionnaires and side effects.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Arizona Cancer Center - North Campus /ID# 227463, Tucson, Arizona, United States

University of Arkansas for Medical Sciences /ID# 225703, Little Rock, Arkansas, United States

Orange Coast Memorial Medical Center /ID# 229632, Fountain Valley, California, United States

Saddleback Memorial Medical Center /ID# 229631, Laguna Hills, California, United States

Long Beach Memorial Medical Ct /ID# 228996, Long Beach, California, United States

University of Southern California /ID# 225443, Los Angeles, California, United States

University of California, Los Angeles /ID# 226887, Los Angeles, California, United States

Cancer Specialists of North Florida /ID# 226826, Jacksonville, Florida, United States

UF Health Cancer Center at Orlando Health /ID# 232626, Orlando, Florida, United States

Southern IL Univ School of Med /ID# 228999, Springfield, Illinois, United States

Parkview Cancer Institute /ID# 227026, Fort Wayne, Indiana, United States

Goshen Center for Cancer Care /ID# 225534, Goshen, Indiana, United States

Mission Cancer and Blood /ID# 261945, Des Moines, Iowa, United States

Norton Cancer Institute - St Matthews /ID# 225420, Louisville, Kentucky, United States

American Oncology Partners of Maryland, PA /ID# 226859, Bethesda, Maryland, United States

Trinity Health St. Joseph Mercy Ann Arbor /ID# 228206, Ypsilanti, Michigan, United States

Metro Minnesota Community Oncology Research Consortium (MMCORC) /ID# 226680, Saint Louis Park, Minnesota, United States

Intermountain Health - St Vincent Regional Hospital - Cancer Centers of Montana /ID# 259014, Billings, Montana, United States

NHO Revive Research Institute, LLC /ID# 261113, Lincoln, Nebraska, United States

Titan Health Partners LLC, d/b/a Astera Cancer Care /ID# 226654, East Brunswick, New Jersey, United States

University of New Mexico /ID# 227332, Albuquerque, New Mexico, United States

Presbyterian Kaseman Hospital /ID# 262084, Albuquerque, New Mexico, United States

Presbyterian Rust Medical Center /ID# 262068, Rio Rancho, New Mexico, United States

NYU Langone Hospital - Long Island /ID# 262412, Mineola, New York, United States

NYU Langone - Laura and Isaac Perlmutter Cancer Center /ID# 226141, New York, New York, United States

Memorial Sloan Kettering Cancer Center-Koch Center /ID# 225379, New York, New York, United States

Novant Health Presbyterian Medical Center /ID# 227753, Charlotte, North Carolina, United States

Novant Health Forsyth Medical Center /ID# 228339, Winston-Salem, North Carolina, United States

University of Cincinnati /ID# 225374, Cincinnati, Ohio, United States

Kaiser Permanente - Northwest /ID# 225488, Portland, Oregon, United States

Millennium Research & Clinical Development /ID# 228284, Kingwood, Texas, United States

Intermountain Medical Center /ID# 231184, Murray, Utah, United States

University of Virginia Cancer Center - West Complex /ID# 225433, Charlottesville, Virginia, United States

Vista Oncology - East Olympia /ID# 229375, Olympia, Washington, United States

Multicare Institute for Research and Innovation /ID# 225432, Tacoma, Washington, United States

Liverpool Hospital /ID# 230072, Liverpool, New South Wales, Australia

Royal Adelaide Hospital /ID# 225683, Adelaide, South Australia, Australia

Monash Medical Centre /ID# 225680, Clayton, Victoria, Australia

Austin Health /ID# 225716, Heidelberg, Victoria, Australia

Alfred Health /ID# 225999, Melbourne, Victoria, Australia

Hollywood Private Hospital /ID# 251837, Nedlands, Western Australia, Australia

Perth Blood Institute Ltd /ID# 225679, Nedlands, Western Australia, Australia

Royal Perth Hospital /ID# 226583, Perth, Western Australia, Australia

Universitaetsklinikum St. Poelten /ID# 234016, Sankt Poelten, Niederoesterreich, Austria

Medizinische Universitaet Wien /ID# 252095, Vienna, Wien, Austria

Klinik Ottakring /ID# 243941, Vienna, Wien, Austria

Landeskrankenhaus Salzburg-Universitaetsklinikum der PMU (LKH) /ID# 228360, Salzburg, , Austria

Cliniques Universitaires UCL Saint-Luc /ID# 225737, Woluwe-Saint-Lambert, Bruxelles-Capitale, Belgium

Hospital La Louviere Site Jolimont - Helora /ID# 225738, La Louvière, Hainaut, Belgium

CHU de Liège /ID# 225952, Liège, Liege, Belgium

Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant /ID# 225742, Yvoir, Namur, Belgium

UZ Gent /ID# 250031, Gent, Oost-Vlaanderen, Belgium

Vitaz /Id# 226153, Sint-Niklaas, Oost-Vlaanderen, Belgium

Universitair Ziekenhuis Leuven /ID# 225951, Leuven, Vlaams-Brabant, Belgium

AZ-Delta /ID# 225736, Roeselare, West-Vlaanderen, Belgium

Institut Jules Bordet /ID# 225954, Anderlecht, , Belgium

ZNA Middelheim /ID# 225741, Antwerp, , Belgium

ZNA Cadix /ID# 264327, Antwerp, , Belgium

AZ Sint-Jan Brugge /ID# 225735, Brugge, , Belgium

Hospital de Clinicas da Universidade Federal do Parana /ID# 226027, Curitiba, Parana, Brazil

Hospital Amaral Carvalho - Fundacao Doutor Amaral Carvalho /ID# 226065, Jaú, Sao Paulo, Brazil

Fundacao Antonio Prudente - AC Camargo Cancer Center /ID# 226809, São Paulo, Sao Paulo, Brazil

Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein /ID# 252832, São Paulo, Sao Paulo, Brazil

Real e Benemérita Associação Portuguesa de Beneficência /ID# 226023, Sao Paulo, , Brazil

Hospital Alemao Oswaldo Cruz /ID# 252833, Sao Paulo, , Brazil

Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao /ID# 226048, Sao Paulo, , Brazil

UMHAT Sveti Georgi /ID# 245780, Plovdiv, , Bulgaria

Acibadem City Clinic Tokuda University Hospital EAD /ID# 244616, Sofia, , Bulgaria

UMHAT Sveti Ivan Rilski /ID# 244615, Sofia, , Bulgaria

SHAT Hematologic Diseases /ID# 250102, Sofia, , Bulgaria

Tom Baker Cancer Centre /ID# 226077, Calgary, Alberta, Canada

BC Cancer - Vancouver /ID# 230573, Vancouver, British Columbia, Canada

William Osler Health System /ID# 250973, Brampton, Ontario, Canada

Juravinski Cancer Centre /ID# 226084, Hamilton, Ontario, Canada

Saskatoon Cancer Centre /ID# 226082, Saskatoon, Saskatchewan, Canada

The Fifth Medical Center of PLA General Hospital /ID# 230941, Beijing, Beijing, China

Beijing Cancer Hospital /ID# 229819, Beijing, Beijing, China

Peking University Third Hospital /ID# 230975, Beijing, Beijing, China

Fujian Provincial Cancer Hospital /ID# 238430, Fuzhou, Fujian, China

The First Affiliated Hospital of Xiamen University /ID# 238426, Xiamen, Fujian, China

Sun Yat-Sen University Cancer Center /ID# 238371, Guangzhou, Guangdong, China

Guangdong Provincial People's Hospital /ID# 230945, Guangzhou, Guangdong, China

Nanfang Hospital of Southern Medical University /ID# 238436, Guangzhou, Guangdong, China

Harbin Medical University Cancer Hospital /Id# 241755, Harbin, Heilongjiang, China

Henan Cancer Hospital /ID# 230398, Zhengzhou, Henan, China

Union Hospital affiliated to Tongji Medical College of Huazhong University of Sc /ID# 234152, Wuhan, Hubei, China

Hubei Cancer Hospital /ID# 232256, Wuhan, Hubei, China

The First Affiliated Hospital of Soochow University /ID# 232569, Suzhou, Jiangsu, China

The Affiliated Hospital of Xuzhou Medical College /ID# 233174, Xuzhou, Jiangsu, China

The First Affiliated Hospital of Nanchang University /ID# 230399, Nanchang, Jiangxi, China

Jiangxi Provincial Cancer Hospital /ID# 233379, Nanchang, Jiangxi, China

The First Hospital of Jilin University /ID# 239618, Changchun, Jilin, China

The First Hospital of China Medical University /ID# 233201, Shenyang, Liaoning, China

Shandong Cancer Hospital /ID# 233200, Jinan, Shandong, China

Fudan University Cancer Hospital /ID# 251516, Shanghai, Shanghai, China

Tianjin Cancer Hospital /ID# 230974, Tianjin, Tianjin, China

Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sc /ID# 259904, Tianjin, Tianjin, China

The First Affiliated Hospital, Zhejiang University School of Medicine /ID# 230387, Hangzhou, Zhejiang, China

The second affiliated hospital of Zhejiang University school of medicine /ID# 231249, Hangzhou, Zhejiang, China

Zhejiang Cancer hospital /ID# 231388, Hangzhou, Zhejiang, China

Clinical Hospital Dubrava /ID# 251809, Zagreb, Grad Zagreb, Croatia

Klinicka bolnica Merkur /ID# 252481, Zagreb, Grad Zagreb, Croatia

Klinicki bolnicki centar Zagreb /ID# 250709, Zagreb, Grad Zagreb, Croatia

Klinicki bolnicki centar Rijeka /ID# 251811, Rijeka, Primorsko-goranska Zupanija, Croatia

Klinicki Bolnicki Centar (KBC) Split /ID# 250729, Split, Splitsko-dalmatinska Zupanija, Croatia

Opca bolnica Dr. Josip Bencevic /ID# 251812, Slavonski Brod, , Croatia

Fakultni nemocnice Brno /ID# 225953, Brno, , Czechia

Fakultni nemocnice Hradec Kralove /ID# 225955, Hradec Kralove, , Czechia

Fakultni Nemocnice Ostrava /ID# 225957, Ostrava, , Czechia

Duplicate_Fakultni Nemocnice v Motole /ID# 225958, Prague, , Czechia

Fakultni nemocnice Kralovske Vinohrady /ID# 225956, Praha, , Czechia

Vseobecna fakultni nemocnice v Praze /ID# 225396, Praha, , Czechia

Rigshospitalet /ID# 226576, Copenhagen Ø, Hovedstaden, Denmark

Aarhus Universitetshospital - Skejby /ID# 226594, Aarhus, Midtjylland, Denmark

Roskilde Sygehus /ID# 226597, Roskilde, Sjælland, Denmark

Odense University Hospital /ID# 226593, Odense C, Syddanmark, Denmark

Sygehus Lillebalt, Vejle /ID# 226592, Vejle, Syddanmark, Denmark

CHU de Nice - Hôpital Archet 1 /ID# 226127, Nice, Alpes-Maritimes, France

Institut Paoli-Calmettes /ID# 226557, Marseille, Bouches-du-Rhone, France

CHU de Rennes - PONTCHAILLOU /ID# 228207, Rennes, Bretagne, France

CHU Dijon /ID# 238345, Dijon, Cote-d Or, France

CHU Limoges - Dupuytren 1 /ID# 234235, Limoges CEDEX 1, Franche-Comte, France

CHU Montpellier - Hôpital Saint Eloi /ID# 228191, Montpellier Cedex 5, Herault, France

CHRU Nancy - Hopitaux de Brabois /ID# 226102, Vandoeuvre-les-Nancy, Meurthe-et-Moselle, France

CHRU Lille - Hopital Claude Huriez /ID# 226101, Lille, Nord, France

CHU de Nantes, Hotel Dieu -HME /ID# 226125, Nantes, Pays-de-la-Loire, France

Centre Hospitalier de la Cote Basque /ID# 249143, Bayonne, Pyrenees-Atlantiques, France

HCL - Hopital Lyon Sud /ID# 227086, Pierre Benite CEDEX, Rhone, France

CHU Amiens-Picardie Site Sud /ID# 238347, Amiens CEDEX 1, Somme, France

CHD Vendée- La Roche-sur-Yon - Les Oudairies /ID# 243899, La Roche Sur Yon, Vendee, France

CHU Poitiers - La miletrie /ID# 226578, Poitiers, Vienne, France

Chu Angers /Id# 245931, Angers, , France

CHU de CAEN - Hopital de la Cote de Nacre /ID# 226582, Caen, , France

Hôpitaux Universitaires Henri Mondor - Hôpital Henri Mondor /ID# 226560, Créteil, , France

CHU Grenoble - Hopital Michallon /ID# 226128, La Tronche, , France

AP-HP - Hopital Saint-Louis /ID# 226126, Paris, , France

Centre Henri Becquerel /ID# 226103, Rouen, , France

Institut Curie - site CLCC René Huguenin /ID# 253519, Saint-cloud, , France

General Hospital of Athens Laiko /ID# 225399, Athens, Attiki, Greece

Alexandra General Hospital /ID# 225402, Athens, Attiki, Greece

University General Hospital Attikon /ID# 225401, Athens, Attiki, Greece

General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 225416, Athens, , Greece

University General Hospital of Ioannina /ID# 225400, Ioannina, , Greece

General University Hospital of Thessaloniki AXEPA /ID# 225398, Thessaloniki, , Greece

Theageneio Anticancer Hospital /ID# 225516, Thessaloniki, , Greece

Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz /ID# 257189, Gyor, Gyor-Moson-Sopron, Hungary

Debreceni Egyetem-Klinikai Kozpont /ID# 226821, Debrecen, Hajdu-Bihar, Hungary

Somogy Varmegyei Kaposi Mor Oktato Korhaz /ID# 245938, Kaposvár, Somogy, Hungary

Tolna Varmegyei Balassa Janos Korhaz /ID# 250063, Szekszard, Tolna, Hungary

Vas Varmegyei Markusovszky Egyetemi Oktatokorhaz /ID# 226846, Szombathely, Vas, Hungary

Semmelweis Egyetem /ID# 227239, Budapest, , Hungary

Orszagos Onkologiai Intezet /ID# 227294, Budapest, , Hungary

Szegedi Tudományegyetem /ID# 226838, Szeged, , Hungary

Rambam Health Care Campus /ID# 225981, Haifa, H_efa, Israel

Meir Medical Center /ID# 225612, Kfar Saba, HaMerkaz, Israel

Assuta Tel Aviv Medical Center /ID# 226066, Tel Aviv, HaMerkaz, Israel

The Chaim Sheba Medical Center /ID# 225600, Ramat Gan, Tel-Aviv, Israel

Tel Aviv Sourasky Medical Center /ID# 225891, Tel Aviv, Tel-Aviv, Israel

Shaare Zedek Medical Center /ID# 259796, Jerusalem, Yerushalayim, Israel

Hadassah /ID# 225614, Jerusalem, Yerushalayim, Israel

Rabin Medical Center /ID# 225862, Haifa, , Israel

Fondazione di Religione e di Culto Casa Sollievo della Sofferenza /ID# 225554, San Giovanni Rotondo, Foggia, Italy

Ospedale San Raffaele IRCCS /ID# 225555, Milan, Milano, Italy

IEO -Istituto Europeo di Oncologia /ID# 225545, Milan, Milano, Italy

Istituto di Candiolo Fondazione del Piemonte per l'Oncologia IRCCS /ID# 225751, Candiolo, Torino, Italy

Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo /ID# 225542, Alessandria, , Italy

Centro di Riferimento Oncologico /ID# 225553, Aviano, , Italy

ASST Spedali civili di Brescia /ID# 225549, Brescia, , Italy

Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRCCS /ID# 252192, Meldola, , Italy

Azienda Ospedaliera Universitaria Federico II /ID# 225543, Napoli, , Italy

Azienda Ospedaliero Universitaria Maggiore della Carita di Novara /ID# 225773, Novara, , Italy

A.O. Ospedali Riuniti Villa Sofia - Cervello /ID# 225541, Palermo, , Italy

Azienda Ospedaliero Universitaria Pisana /ID# 225575, Pisa, , Italy

Ospedale Santa Maria delle Croci /ID# 225571, Ravenna, , Italy

NHO Nagoya Medical Center /ID# 230677, Nagoya-shi, Aichi, Japan

Aichi Cancer Center Hospital /ID# 226090, Nagoya-shi, Aichi, Japan

National Cancer Center Hospital East /ID# 250151, Kashiwa-shi, Chiba, Japan

Matsuyama Red Cross Hospital /ID# 251068, Matsuyama-shi, Ehime, Japan

National Hospital Organization Kyushu Cancer Center /ID# 251622, Fukuoka-shi, Fukuoka, Japan

Kyushu University Hospital /ID# 226091, Fukuoka-shi, Fukuoka, Japan

Fukushima Medical University Hospital /ID# 250869, Fukushima-shi, Fukushima, Japan

Hokkaido University Hospital /ID# 250149, Sapporo-shi, Hokkaido, Japan

Kobe City Medical Center General Hospital /ID# 250597, Kobe-shi, Hyogo, Japan

University of Tsukuba Hospital /ID# 251282, Tsukuba-shi, Ibaraki, Japan

Kanazawa University Hospital /ID# 251770, Kanazawa-shi, Ishikawa, Japan

Kagoshima University Hospital /ID# 250163, Kagoshima-shi, Kagoshima, Japan

Tokai University Hospital- Isehara Campus /ID# 251281, Isehara, Kanagawa, Japan

Tohoku University Hospital /ID# 250150, Sendai-shi, Miyagi, Japan

Kindai University Hospital /ID# 250160, Osakasayama-shi, Osaka, Japan

Osaka University Hospital /ID# 251283, Suita-shi, Osaka, Japan

National Cancer Center Hospital /ID# 226089, Chuo-ku, Tokyo, Japan

The Cancer Institute Hospital Of JFCR /ID# 230269, Koto, Tokyo, Japan

Yamagata University Hospital /ID# 230003, Yamagata-shi, Yamagata, Japan

Okayama University Hospital /ID# 250161, Okayama, , Japan

Inje University - Busan Paik Hospital /ID# 232262, Busan, Busan Gwang Yeogsi, Korea, Republic of

Seoul National University Bundang Hospital /ID# 225763, Seongnam-si, Gyeonggido, Korea, Republic of

Keimyung University Dongsan Hospital /ID# 232264, Daegu, Gyeongsangbugdo, Korea, Republic of

Dong-A University Medical Center /ID# 228451, Busan, Gyeongsangnamdo, Korea, Republic of

Jeonbuk National University Hospital /ID# 232263, Jeonju, Jeonrabugdo, Korea, Republic of

Asan Medical Center /ID# 225758, Seoul, Seoul Teugbyeolsi, Korea, Republic of

The Catholic University of Korea, Seoul St. Marys Hospital /ID# 225761, Seoul, Seoul Teugbyeolsi, Korea, Republic of

Ulsan University Hospital /ID# 226971, Ulsan, Ulsan Gwang Yeogsi, Korea, Republic of

Seoul National University Hospital /ID# 225760, Seoul, , Korea, Republic of

Samsung Medical Center /ID# 225759, Seoul, , Korea, Republic of

Flevo Ziekenhuis /ID# 229606, Almere, Flevoland, Netherlands

Gelre Ziekenhuizen /ID# 229762, Apeldoorn, Gelderland, Netherlands

Amphia Ziekenhuis /ID# 229550, Breda, Noord-Brabant, Netherlands

Spaarne Gasthuis, Haarlem Zuid /ID# 229621, Haarlem, Noord-Holland, Netherlands

Tergooi /ID# 229772, Hilversum, Noord-Holland, Netherlands

Dijklander Ziekenhuis /ID# 229900, Hoorn Nh, Noord-Holland, Netherlands

Zaans Medisch Centrum /ID# 230614, Zaandam, Noord-Holland, Netherlands

Albert Schweitzer Ziekenhuis /ID# 229560, Dordrecht, Zuid-Holland, Netherlands

Noordwest Ziekenhuisgroep /ID# 230613, Alkmaar, , Netherlands

Meander Medisch Centrum /ID# 229608, Amersfoort, , Netherlands

Vrije Universiteit Medisch Centrum /ID# 225608, Amsterdam, , Netherlands

Onze Lieve Vrouwe Gasthuis /ID# 229761, Amsterdam, , Netherlands

Haaglanden Medisch Centrum /ID# 229686, Den Haag, , Netherlands

Deventer Ziekenhuis /ID# 229937, Deventer, , Netherlands

Catharina Ziekenhuis /ID# 230465, Eindhoven, , Netherlands

Maxima Medisch Centrum /ID# 225603, Eindhoven, , Netherlands

Medisch Spectrum Twente /ID# 225610, Enschede, , Netherlands

Universitair Medisch Centrum Groningen /ID# 225602, Groningen, , Netherlands

Medisch Centrum Leeuwarden /ID# 225605, Leeuwarden, , Netherlands

Leids Universitair Medisch Centrum /ID# 225606, Leiden, , Netherlands

Maastricht Universitair Medisch Centrum /ID# 225607, Maastricht, , Netherlands

St. Antonius Ziekenhuis /ID# 229901, Nieuwegein, , Netherlands

Canisius-Wilhelmina Ziekenhuis /ID# 231291, Nijmegen, , Netherlands

Jeroen Bosch Ziekenhuis /ID# 229765, S Hertogenbosch, , Netherlands

Elisabeth Tweesteden Ziekenhuis /ID# 229773, Tilburg, , Netherlands

Diakonessenhuis /ID# 251793, Utrecht, , Netherlands

North Shore Hospital /ID# 250992, Takapuna, Auckland, New Zealand

Christchurch Hospital /ID# 250993, Christchurch, Canterbury, New Zealand

Wojewodzki Szpital Specjalistyczny im. Janusza Korczaka /ID# 228723, Slupsk, Pomorskie, Poland

Swietokrzyskie Centrum Onkologii /ID# 225986, Kielce, Swietokrzyskie, Poland

SP ZOZ MSWiA z Warminsko-Mazurskim Centrum Onkologii /ID# 225985, Olsztyn, Warminsko-mazurskie, Poland

ARS-MEDICAL Sp. z o.o. /ID# 225848, Pila, Wielkopolskie, Poland

Centrum Medyczne Promed - Skorzewo /ID# 227236, Skorzewo, Wielkopolskie, Poland

2CA-Braga, Hospital de Braga /ID# 249112, Braga, , Portugal

IPO Lisboa FG, EPE /ID# 249109, Lisboa, , Portugal

Centro Hospitalar Universitario de Lisboa Norte, EPE - Hospital de Santa Maria /ID# 249111, Lisboa, , Portugal

IPO Porto FG, EPE /ID# 249110, Porto, , Portugal

Hematology and Oncology Institute /ID# 230054, Manati, , Puerto Rico

Pan American Center for Oncology Trials, LLC /ID# 230052, Rio Piedras, , Puerto Rico

Narodny onkologicky ustav /ID# 238847, Bratislava, Nitriansky Kraj, Slovakia

Wits Clinical Research /ID# 227799, Johannesburg, Gauteng, South Africa

Wits Clinical Research /ID# 227803, Johannesburg, Gauteng, South Africa

Alberts Cellular Therapy /ID# 227798, Pretoria, Gauteng, South Africa

Haemalife Inc. /ID# 243391, Kuilsrivier, Western Cape, South Africa

Instituto Catalan de Oncologia (ICO) Badalona /ID# 228063, Badalona, Barcelona, Spain

Instituto Catalan de Oncologia (ICO) L'Hospitalet /ID# 227393, Hospitalet de Llobregat, Barcelona, Spain

Hospital Universitario Reina Sofia /ID# 225806, Córdoba, Cordoba, Spain

Hospital Clinico Universitario Virgen de la Arrixaca /ID# 255381, El Palmar, Murcia, Spain

Clinica Universidad de Navarra - Pamplona /ID# 225809, Pamplona, Navarra, Spain

Hospital Parc de Salut del Mar /ID# 225810, Barcelona, , Spain

Hospital Universitario Vall d'Hebron /ID# 225811, Barcelona, , Spain

Hospital Clinic de Barcelona /ID# 226651, Barcelona, , Spain

Hospital Santa Creu i Sant Pau /ID# 225813, Barcelona, , Spain

CLINICA UNIVERSIDAD DE NAVARRA-Madrid /ID# 228228, Madrid, , Spain

Hospital Universitario Infanta Leonor /ID# 225816, Madrid, , Spain

MD Anderson Madrid /ID# 225817, Madrid, , Spain

Hospital Universitario Ramon y Cajal /ID# 241750, Madrid, , Spain

Hospital Universitario Fundacion Jimenez Diaz /ID# 225804, Madrid, , Spain

Hospital Universitario 12 de Octubre /ID# 225815, Madrid, , Spain

Hospital Clinico Universitario de Valencia /ID# 225818, Valencia, , Spain

Skane University Hospital Lund /ID# 227285, Lund, Skane Lan, Sweden

Sodra Alvsborgs sjukhus /ID# 228885, Boras, Vastra Gotalands Lan, Sweden

Sahlgrenska Universitetssjukhuset /ID# 250089, Göteborg, Vastra Gotalands Lan, Sweden

Linkoping University Hospital /ID# 233521, Linkoping, , Sweden

Karolinska Universitetssjukhuset Solna /ID# 229284, Solna, , Sweden

Kantonsspital Aarau AG /ID# 229112, Aarau, Aargau, Switzerland

Spital Thun /ID# 229499, Thun, Bern, Switzerland

KSW Kantonsspital Winterthur /ID# 241631, Winterthur, Zuerich, Switzerland

Kaohsiung Chang Gung Memorial Hospital /ID# 226670, Kaohsiung City, Kaohsiung, Taiwan

China Medical University Hospital /ID# 226188, Taichung, , Taiwan

Taichung Veterans General Hospital /ID# 226674, Taichung, , Taiwan

National Cheng Kung University Hospital /ID# 226671, Tainan, , Taiwan

Anadolu Saglik Merkezi /ID# 225777, Dilovası, Kocaeli, Turkey

Ankara Universitesi Fakultesi /ID# 227331, Ankara, , Turkey

Inonu University Medical Faculty /ID# 226572, Malatya, , Turkey

Ondokuz Mayis Universitesi Tip /ID# 251247, Samsun, , Turkey

Karadeniz University /ID# 226573, Trabzon, , Turkey

Baskent Universitesi Adana Uyg. ve Arast. Merkezi Yuregir Baskent Hastanesi /ID# 225921, Yuregir, , Turkey

Imperial College London - St Mary's Hospital /ID# 242215, London, London, City Of, United Kingdom

Norfolk and Norwich University Hospitals NHS Foundation Trust /ID# 226692, Norwich, Norfolk, United Kingdom

University Hospitals Birmingham NHS Foundation Trust /ID# 229197, Birmingham, , United Kingdom

Contact Details

Name: ABBVIE INC.

Affiliation: AbbVie

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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