Spots Global Cancer Trial Database for A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312)
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Trial Identification
Brief Title: A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312)
Official Title: Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Acalabrutinib in Combination With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Subjects ≤75 Years With Previously Untreated Non-GCB DLBCL
Study ID: NCT04529772
Conditions
Study Description
Brief Summary: Phase 3 randomized, double-blind, placebo-controlled, study assessing the efficacy and safety of acalabrutinib plus rituximab,cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) vs placebo plus R-CHOP in subjects ≤75 years of age with previously untreated non-germinal center diffuse large B-cell lymphoma.
Detailed Description: Phase 3 randomized, double-blind, placebo-controlled, study to evaluate the efficacy and safety of acalabrutinib plus rituximab,cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) as compared with placebo plus R-CHOP in subjects ≤75 years of age with previously untreated non-germinal center diffuse large B-cell lymphoma (activated B-cell (ABC) and unclassified).
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, Tucson, Arizona, United States
Research Site, Little Rock, Arkansas, United States
Research Site, Irvine, California, United States
Research Site, Aurora, Colorado, United States
Research Site, Norwich, Connecticut, United States
Research Site, Fort Myers, Florida, United States
Research Site, Orlando, Florida, United States
Research Site, Saint Petersburg, Florida, United States
Research Site, Tallahassee, Florida, United States
Research Site, West Palm Beach, Florida, United States
Research Site, Fort Wayne, Indiana, United States
Research Site, Des Moines, Iowa, United States
Research Site, Wichita, Kansas, United States
Research Site, Louisville, Kentucky, United States
Research Site, Baltimore, Maryland, United States
Research Site, Grand Rapids, Michigan, United States
Research Site, Minneapolis, Minnesota, United States
Research Site, Saint Louis, Missouri, United States
Research Site, Albany, New York, United States
Research Site, New York, New York, United States
Research Site, New York, New York, United States
Research Site, Stony Brook, New York, United States
Research Site, Charlotte, North Carolina, United States
Research Site, Winston-Salem, North Carolina, United States
Research Site, Eugene, Oregon, United States
Research Site, Portland, Oregon, United States
Research Site, Philadelphia, Pennsylvania, United States
Research Site, Pittsburgh, Pennsylvania, United States
Research Site, Nashville, Tennessee, United States
Research Site, Fort Sam Houston, Texas, United States
Research Site, Lubbock, Texas, United States
Research Site, Salem, Virginia, United States
Research Site, Adelaide, , Australia
Research Site, Camperdown, , Australia
Research Site, Clayton, , Australia
Research Site, Darlinghurst, , Australia
Research Site, Heidelberg, , Australia
Research Site, Hobart, , Australia
Research Site, Kogarah, , Australia
Research Site, Liverpool, , Australia
Research Site, Nedlands, , Australia
Research Site, Westmead, , Australia
Research Site, Linz, , Austria
Research Site, Salzburg, , Austria
Research Site, Wels, , Austria
Research Site, Antwerpen, , Belgium
Research Site, Brugge, , Belgium
Research Site, La Louvière, , Belgium
Research Site, Curitiba, , Brazil
Research Site, Florianopolis, , Brazil
Research Site, Goiania, , Brazil
Research Site, Passo Fundo, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Ribeirão Preto, , Brazil
Research Site, Rio de Janeiro, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, São Paulo, , Brazil
Research Site, São Paulo, , Brazil
Research Site, Vancouver, British Columbia, Canada
Research Site, Toronto, CA, Canada
Research Site, Winnipeg, Manitoba, Canada
Research Site, London, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Lévis, Quebec, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Ottawa, , Canada
Research Site, Quebec, , Canada
Research Site, Beijing, , China
Research Site, Beijing, , China
Research Site, Changchun, , China
Research Site, Chengdu, , China
Research Site, Guangzhou, , China
Research Site, Guangzhou, , China
Research Site, Guangzhou, , China
Research Site, Hangzhou, , China
Research Site, Hangzhou, , China
Research Site, Harbin, , China
Research Site, Jinan, , China
Research Site, Luoyang, , China
Research Site, Nanchang, , China
Research Site, Nanning, , China
Research Site, Shanghai, , China
Research Site, Shanghai, , China
Research Site, Shenyang, , China
Research Site, Shenyang, , China
Research Site, Shijiazhuang, , China
Research Site, Suzhou, , China
Research Site, Tianjin, , China
Research Site, Tianjin, , China
Research Site, Wuhan, , China
Research Site, Wuhan, , China
Research Site, Xiamen, , China
Research Site, Zhengzhou, , China
Research Site, Brno, , Czechia
Research Site, Hradec Kralove, , Czechia
Research Site, Ostrava - Poruba, , Czechia
Research Site, Plzen, , Czechia
Research Site, Praha 10, , Czechia
Research Site, Praha 2, , Czechia
Research Site, Brest, , France
Research Site, Caen Cedex 9, , France
Research Site, Marseille cedex 5, , France
Research Site, Montpellier, , France
Research Site, Nantes, , France
Research Site, Pessac, , France
Research Site, Pierre Benite, , France
Research Site, Rennes Cedex 9, , France
Research Site, Toulouse, , France
Research Site, Bamberg, , Germany
Research Site, Berlin, , Germany
Research Site, Dresden, , Germany
Research Site, Homburg, , Germany
Research Site, Neumünster, , Germany
Research Site, Bangalore, , India
Research Site, Delhi, , India
Research Site, Kochi, , India
Research Site, Mumbai, , India
Research Site, Nashik, , India
Research Site, Pune, , India
Research Site, Afula, , Israel
Research Site, Ashdod, , Israel
Research Site, Beer Sheba, , Israel
Research Site, Haifa, , Israel
Research Site, Haifa, , Israel
Research Site, Haifa, , Israel
Research Site, Holon, , Israel
Research Site, Jerusalem, , Israel
Research Site, Jerusalem, , Israel
Research Site, Nahariya, , Israel
Research Site, Petah Tikva, , Israel
Research Site, Ramat Gan, , Israel
Research Site, Tel Aviv, , Israel
Research Site, Zerifin, , Israel
Research Site, Bari, , Italy
Research Site, Bergamo, , Italy
Research Site, Bologna, , Italy
Research Site, Firenze, , Italy
Research Site, Genova, , Italy
Research Site, Meldola, , Italy
Research Site, Milano, , Italy
Research Site, Milan, , Italy
Research Site, Novara, , Italy
Research Site, Palermo, , Italy
Research Site, Pavia, , Italy
Research Site, Pisa, , Italy
Research Site, Ravenna, , Italy
Research Site, Reggio Emilia, , Italy
Research Site, Roma, , Italy
Research Site, Roma, , Italy
Research Site, Siena, , Italy
Research Site, Torino, , Italy
Research Site, Tricase, , Italy
Research Site, Venezia, , Italy
Research Site, Chiba-shi, , Japan
Research Site, Chuo-ku, , Japan
Research Site, Fukuoka-shi, , Japan
Research Site, Itabashi-ku, , Japan
Research Site, Kahoku-gun, , Japan
Research Site, Kashiwa, , Japan
Research Site, Kobe-shi, , Japan
Research Site, Koto-ku, , Japan
Research Site, Kumamoto-shi, , Japan
Research Site, Kumamoto-shi, , Japan
Research Site, Kyoto-city, , Japan
Research Site, Matsuyama-shi, , Japan
Research Site, Nagasaki-shi, , Japan
Research Site, Nagoya-shi, , Japan
Research Site, Nagoya-shi, , Japan
Research Site, Nagoya-shi, , Japan
Research Site, Niigata-shi, , Japan
Research Site, Okayama-shi, , Japan
Research Site, Osaka-shi, , Japan
Research Site, Sapporo-shi, , Japan
Research Site, Sendai-shi, , Japan
Research Site, Shimotsuke-shi, , Japan
Research Site, Tsu-shi, , Japan
Research Site, Busan, , Korea, Republic of
Research Site, Busan, , Korea, Republic of
Research Site, Goyang-si, , Korea, Republic of
Research Site, Jeonju-si, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Suwon-si, , Korea, Republic of
Research Site, Chihuahua, , Mexico
Research Site, Monterrey, , Mexico
Research Site, Gdańsk, , Poland
Research Site, Kraków, , Poland
Research Site, Lublin, , Poland
Research Site, Warszawa, , Poland
Research Site, Wrocław, , Poland
Research Site, Łódź, , Poland
Research Site, Braga, , Portugal
Research Site, Lisboa, , Portugal
Research Site, Lisboa, , Portugal
Research Site, Lisboa, , Portugal
Research Site, Matosinhos, , Portugal
Research Site, Porto, , Portugal
Research Site, Porto, , Portugal
Research Site, Vila Nova de Gaia, , Portugal
Research Site, Chelyabinsk, , Russian Federation
Research Site, Moscow, , Russian Federation
Research Site, Saint Petersburg, , Russian Federation
Research Site, St. Petersburg, , Russian Federation
Research Site, Alcalá De Henares, , Spain
Research Site, Barcelona, , Spain
Research Site, Barcelona, , Spain
Research Site, Gijón, , Spain
Research Site, L'Hospitalet de Llobregat, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Palma, , Spain
Research Site, Pamplona, , Spain
Research Site, Pozuelo de Alarcón, , Spain
Research Site, Salamanca, , Spain
Research Site, Sevilla, , Spain
Research Site, Valencia, , Spain
Research Site, Kaohsiung, , Taiwan
Research Site, Tainan, , Taiwan
Research Site, Tainan, , Taiwan
Research Site, Taipei 112, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, Taoyuan City, , Taiwan
Research Site, Ankara, , Turkey
Research Site, Ankara, , Turkey
Research Site, Ankara, , Turkey
Research Site, Balcova, , Turkey
Research Site, Edirne, , Turkey
Research Site, Izmir, , Turkey
Research Site, Kayseri, , Turkey
Research Site, Mersin, , Turkey
Research Site, Samsun, , Turkey
Research Site, Trabzon, , Turkey
Research Site, Cherkasy, , Ukraine
Research Site, Khmelnytskyi, , Ukraine
Research Site, Kyiv, , Ukraine
Research Site, Kyiv, , Ukraine
Research Site, Lviv, , Ukraine
Research Site, Mykolayiv, , Ukraine
Research Site, Zaporizhzhia, , Ukraine
Contact Details
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