Spots Global Cancer Trial Database for A Trial to Evaluate the Efficacy and Safety of Tafasitamab With Bendamustine (BEN) Versus Rituximab (RTX) With BEN in Adult Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)
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Trial Identification
Brief Title: A Trial to Evaluate the Efficacy and Safety of Tafasitamab With Bendamustine (BEN) Versus Rituximab (RTX) With BEN in Adult Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)
Official Title: A Phase 2/3, Randomised, Multicentre Study of Tafasitamab With Bendamustine Versus Rituximab With Bendamustine in Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (R-R DLBCL) Who Are Not Eligible for High-Dose Chemotherapy (HDC) and Autologous Stem-Cell Transplantation (ASCT)
Study ID: NCT02763319
Conditions
Study Description
Brief Summary: The purpose of the study is to compare the safety and efficacy of Tafasitamab with BEN versus RTX with BEN in adult patients with relapsed of refractory DLBCL.
Detailed Description: This is a randomised, two-arm, multicentre, open-label phase II/III efficacy and safety study of Tafasitamab in combination with BEN versus RTX in combination with BEN given to adult patients who have relapsed after or are refractory to at least one but no more than three prior systemic therapies and have failed, or are not candidates for HDC and ASCT, and have thus exhausted their therapeutic options of demonstrated clinical benefit. At least one prior therapy line must have included a CD20-targeted therapy.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
MorphoSys Research Site, Anaheim, California, United States
MorphoSys Research Site, Bakersfield, California, United States
Morphosys Research Site, Burbank, California, United States
Morphosys Research Site, Fresno, California, United States
MorphoSys Research Site, Los Angeles, California, United States
MorphoSys Research Site, Whittier, California, United States
MorphoSys Research Site, Plainville, Connecticut, United States
MorphoSys Research Site, Skokie, Illinois, United States
MorphoSys Research Site, Detroit, Michigan, United States
MorphoSys Research Site, Rochester, Minnesota, United States
MorphoSys Research Site, Hattiesburg, Mississippi, United States
Morphosys Research site, Jackson, Mississippi, United States
Morphosys Research Site, Morristown, New Jersey, United States
MorphoSys Research Site, New York, New York, United States
MorphoSys Research Site, Stony Brook, New York, United States
MorphoSys Research Site, Oklahoma City, Oklahoma, United States
MorphoSys Research Site, Knoxville, Tennessee, United States
Morphosys Research Site, Lubbock, Texas, United States
MorphoSys Research Site, Adelaide, , Australia
MorphoSys Research Site, Albury, , Australia
MorphoSys Research Site, Bedford Park, , Australia
MorphoSys Research Site, Box Hill, , Australia
MorphoSys Research Site, Concord, , Australia
MorphoSys Research Site, Frankston, , Australia
MorphoSys Research SIte, Garran, , Australia
MorphoSys Research Site, Geelong, , Australia
MorphoSys Research Site, Gosford, , Australia
MorphoSys Research Site, Nedlands, , Australia
MorphoSys Research Site, South Brisbane, , Australia
MorphoSys Research Site, St. Albans, , Australia
MorphoSys Research Site, Innsbruck, , Austria
Morphosys Research Site, Edmonton, Alberta, Canada
MorphoSys Research Site, Winnipeg, Manitoba, Canada
MorphoSys Research Site, Saint John, New Brunswick, Canada
Morphosys Research Site, Saint John's, Newfoundland and Labrador, Canada
MorphoSys Research Site, Kingston, Ontario, Canada
MorphoSys Research Site, Greenfield Park, Quebec, Canada
Morphosys Research Site, Montréal, Quebec, Canada
MorphoSys Research Site, Saskatoon, , Canada
MorphoSys Research Site, Zagreb, , Croatia
MorphoSys Research Site, Hradec Kralove, , Czechia
Morphosys Research site, Olomouc, , Czechia
Morphosys Research Site, Prague, , Czechia
MorphoSys Research Site, Prague, , Czechia
MorphoSys Research Site, Oulu, , Finland
MorphoSys Research Site, Tampere, , Finland
MorphoSys Research Site, Grenoble, , France
MorphoSys Research Site, Le Mans, , France
MorphoSys Research Site, Aachen, , Germany
MorphoSys Research Site, Berlin, , Germany
MorphoSys Research Site, Berlin, , Germany
MorphoSys Research Site, Düsseldorf, , Germany
MorphoSys Research Site, Giessen, , Germany
Morphosys Research Site, Homburg, , Germany
MorphoSys Research Site, Leipzig, , Germany
MorphoSys Research Site, Mainz, , Germany
MorphoSys Research Site, Munich, , Germany
MorphoSys Research Site, Munich, , Germany
MorphoSys Research Site, Mutlangen, , Germany
Morphosys Research Site, Münster, , Germany
MorphoSys Research Site, Rostock, , Germany
MorphoSys Research Site, Stuttgart, , Germany
MorphoSys Research Site, Stuttgart, , Germany
MorphoSys, Traunstein, , Germany
MorphoSys, Budapest, , Hungary
MorphoSys Research Site, Debrecen, , Hungary
MorphoSys Research Site, Győr, , Hungary
MorphoSys, Szeged, , Hungary
MorphoSys Research Site, Haifa, , Israel
MorphoSys Research Site, Jerusalem, , Israel
MorphoSys Research Site, Jerusalem, , Israel
MorphoSys Research Site, Kfar Saba, , Israel
MorphoSys Research Site, Tel Aviv, , Israel
MorphoSys Research Site, Alessandria, , Italy
MorphoSys Research Site, Bologna, , Italy
MorphoSys Research Site, Campobasso, , Italy
MorphoSys Research Site, Cona, , Italy
MorphoSys Research Site, Genova, , Italy
MorphoSys Research Site, Lecce, , Italy
MorphoSys Research Site, Meldola, , Italy
MorphoSys Research Site, Monza, , Italy
MorphoSys Research Site, Napoli, , Italy
Morphosys Research Site, Novara, , Italy
MorphoSys Research Site, Orbassano, , Italy
MorphoSys Research Site, Parma, , Italy
MorphoSys Research Site, Pavia, , Italy
MorphoSys Research Site, Pisa, , Italy
MorphoSys Research Site, Ravenna, , Italy
MorphoSys Research Site, Reggio Emilia, , Italy
MorphoSys Research Site, Rimini, , Italy
MorphoSys Research Site, Rome, , Italy
MorphoSys Research Site, Rome, , Italy
Morphosys Research Site, Terni, , Italy
MorphoSys Research Site, Turin, , Italy
Morphosys Research Site, Turin, , Italy
MorphoSys Research Site, Busan, , Korea, Republic of
MorphoSys Research Site, Goyang-si, , Korea, Republic of
MorphoSys Research Site, Incheon, , Korea, Republic of
MorphoSys Research Site, Jeonju, , Korea, Republic of
MorphoSys Research Site, Seongnam, , Korea, Republic of
MorphoSys Research Site, Seoul, , Korea, Republic of
MorphoSys Research Site, Seoul, , Korea, Republic of
MorphoSys Research Site, Seoul, , Korea, Republic of
MorphoSys Research Site, Seoul, , Korea, Republic of
MorphoSys Research Site, Ulsan, , Korea, Republic of
MorphoSys Research Site, Addington, , New Zealand
MorphoSys Research Site, Auckland, , New Zealand
MorphoSys Research Site, Grafton, , New Zealand
Morphosys Research Site, Bydgoszcz, , Poland
MorphoSys Research Site, Gdynia, , Poland
MorphoSys Research Site, Kraków, , Poland
MorphoSys Research Site, Legnica, , Poland
MorphoSys Research Site, Lodz, , Poland
MorphoSys Research Site, Lublin, , Poland
Morphosys Research Site, Warszawa, , Poland
MorphoSys Research Site, Wrocław, , Poland
MorphoSys Research Site, Braga, , Portugal
MorphoSys Research Site, Coimbra, , Portugal
MorphoSys Research Site, Coimbra, , Portugal
MorphoSys Research Site, Matosinhos, , Portugal
MorphoSys Research Site, Porto, , Portugal
MorphoSys Research Site, Porto, , Portugal
MorphoSys Research Site, Pragal, , Portugal
MorphoSys Research Site, Bucharest, , Romania
MorphoSys Research Site, Bucharest, , Romania
MorphoSys Research Site, Iaşi, , Romania
MorphoSys Research Site, Belgrade, , Serbia
MorphoSys Research Site, Kragujevac, , Serbia
MorphoSys Research Site, Singapore, , Singapore
MorphoSys Research Site, Singapore, , Singapore
MorphoSys Research Site, Singapore, , Singapore
MorphoSys Research Site, Singapore, , Singapore
MorphoSys Research Site, Cadiz, , Spain
MorphoSys Research Site, Girona, , Spain
MorphoSys Research Site, L'Hospitalet De Llobregat, , Spain
MorphoSys Research Site, Madrid, , Spain
MorphoSys Research Site, Madrid, , Spain
MorphoSys Research Site, Madrid, , Spain
MorphoSys Research Site, Palma de Mallorca, , Spain
MorphoSys Research Site, Pamplona, , Spain
MorphoSys Research Site, Pozuelo De Alarcón, , Spain
MorphoSys, Sabadell, , Spain
MorphoSys Research Site, Salamanca, , Spain
MorphoSys Research Site, Valencia, , Spain
Morphosys Research Site, Chang Hua, , Taiwan
Morphosys Research Site, Hualien City, , Taiwan
Morphosys Research Site, Taichung City, , Taiwan
MorphoSys Research Site, Adana, , Turkey
MorphoSys Research Site, Ankara, , Turkey
MorphoSys Research Site, Ankara, , Turkey
MorphoSys Research Site, Bornova, , Turkey
MorphoSys Research Site, Gaziantep, , Turkey
MorphoSys Research Site, İzmir, , Turkey
MorphoSys Research Site, Manisa, , Turkey
MorphoSys Research Site, Samsun, , Turkey
Morphosys Research Site, Birmingham, , United Kingdom
MorphoSys Research Site, Leeds, , United Kingdom
MorphoSys Research Site, Southend on Sea, , United Kingdom
Contact Details
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