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Spots Global Cancer Trial Database for A Study of Navitoclax in Addition to Bendamustine and Rituximab in Patients With Relapsed Diffuse Large B-Cell Lymphoma (NAVIGATE)

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Trial Identification

Brief Title: A Study of Navitoclax in Addition to Bendamustine and Rituximab in Patients With Relapsed Diffuse Large B-Cell Lymphoma (NAVIGATE)

Official Title: A Phase II, Multicenter, Randomized, Controlled, Open-Label Study of Bendamustine + Rituximab With or Without Navitoclax in Patients With Relapsed Diffuse Large B-Cell Lymphoma

Study ID: NCT01423539

Study Description

Brief Summary: This randomized, open-label, multicenter study will evaluate the efficacy and safety of navitoclax in addition to bendamustine and rituximab in patients with relapsed diffuse large B-cell lymphoma. Patients will be randomized to receive navitoclax in addition to bendamustine and rituximab or bendamustine and rituximab alone for 6 cycles.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

, Fountain Valley, California, United States

, Hudson, Florida, United States

, Lawrenceville, Georgia, United States

, Centralia, Illinois, United States

, Harvey, Illinois, United States

, Terre Haute, Indiana, United States

, Hazard, Kentucky, United States

, Paducah, Kentucky, United States

, Rockville, Maryland, United States

, Jefferson City, Missouri, United States

, Great Falls, Montana, United States

, Newark, Ohio, United States

, Nashville, Tennessee, United States

Contact Details

Name: Clinical Trials

Affiliation: Genentech, Inc.

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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