Spots Global Cancer Trial Database for A Pilot Study of Chemo-prevention of Green Tea in Women With Ductal Carcinoma in Situ
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Trial Identification
Brief Title: A Pilot Study of Chemo-prevention of Green Tea in Women With Ductal Carcinoma in Situ
Official Title: A Pilot Study of Chemo-prevention of Green Tea in Women With Ductal Carcinoma in Situ (DCIS)
Study ID: NCT01060345
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study is to find molecular signs (biomarkers) to better understand the role of green tea as an anti-cancer and anti-inflammation agent in women with newly-diagnosed ductal carcinoma in situ (DCIS).
Detailed Description: Many studies have shown that green tea may have anti-cancer and anti-inflammatory effects in cancer cells and animal models of breast cancer. Some studies have found that Asian women who drink many cups of green tea have lower rates of breast cancer. Green tea may have an effect on proliferative and inflammatory pathways. Women with ductal carcinoma in situ (DCIS) have been found to have inflammation in the breast tissue surrounding DCIS lesions. Inflammatory pathways are being studied for a possible link to cancer. This study is designed to evaluate changes in biomarkers of proliferation, inflammation, and angiogenesis in response to green tea intake.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
The University of Chicago, Chicago, Illinois, United States
Contact Details
Name: Nora Jaskowiak, MD
Affiliation: University of Chicago
Role: PRINCIPAL_INVESTIGATOR
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