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Brief Title: Coxib-inhibition of Duodenal Polyp Growth in FAP
Official Title: Coxib-inhibition of Duodenal Polyp Growth in Familial Adenomatous Polyposis
Study ID: NCT00844727
Brief Summary: Preliminary data indicate a protective effect on the development of duodenal polyps by coxib treatment. The hypothesis of the present study is that normal therapy doses of rofecoxib for 1 year would stop or reverse the development of premalignant adenomatous lesions in the duodenal mucosa of FAP patients.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Dept of Medicine, Rikshospitalet, Oslo, , Norway