Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Musculoskeletal Diseases

Symptoms and General Pathology

Breast Neoplasms

Joint Diseases

Arthralgia

Breast Diseases

Skin Diseases

Menopause

Antineoplastic Agents

All Drugs and Chemicals

Anastrozole

Antineoplastic Agents, Hormonal

Aromatase Inhibitors

Enzyme Inhibitors

Estrogens

Estrogen Antagonists

Estrogen Receptor Antagonists

Hormones

Hormone Antagonists

AstraZeneca France Medical Director, MD

The purpose of this study is to describe the joint symptoms and structural joint changes under anastrozole as adjuvant treatment in postmenopausal women with early breast cancer.

Arthralgia During Anastrozole Therapy for Breast Cancer

A Multicentre, Open Study Assessing Joint Disorders Under ARIMIDEX® (1mg/Day) as Adjuvant Treatment in Post Menopausal Women With Early Breast Cancer

Functional index of cochin score (from 0 to 90) : sum up of 18 questions on activities involving hands (each question scored from 0 = yes without difficulties (best) to 5 = impossible (worst)) based on 99 patients due to missing values.

Results are based on 97 patients due to missing values

X ray evaluation of arthritis in 30 articulations ; each articulation scored from (0 = no arthritis to 4 = severe arthritis) based on 92 patients due to missing values

X ray assessment on hands and wrists based on 99 patients due to missing values

Treatment compliance. results based on 109 patients due to missing values

AstraZeneca

110 participants were included in the safety population, those who had taken at least one dose of treatment

Anastrozole 1 mg

Age Continuous

Sex: Female, Male

Gerard Lynch

Number of Participants With New Events of Arthralgia

Functional Index of Cochin at 12 Months in Patients Under Anastrozole.

Serum Collagen Degradation Type I - CTX-I at 12 Months in Patients Under Anastrozole

Kellgren and Lawrence Score at 12 Months in Patients Under Anastrozole

Synovial Membrane Thickness at 12 Months in Patients Under Anastrozole

Percentage of Participant With Therapeutic Maintenance Under Anastrozole

Overall Study

Spots Global Cancer Trial Database for Arthralgia During Anastrozole Therapy for Breast Cancer

Trial Identification

Conditions

Interventions

Study Description

Keywords

Eligibility

Locations

Contact Details

Useful links and downloads for this trial