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Brief Title: AZD9291 US Expanded Access Program
Official Title: A Multi-center, AZD9291 Expanded Access Program for the Treatment of Patients With Advanced/Metastatic EGFR T790M Mutation-positive Non-small Cell Lung Cancer (NSCLC) Who Have Received Prior EGFR TKI Therapy
Study ID: NCT02451852
Brief Summary: To provide access to AZD9291 for adult patients with advanced/metastatic, epidermal growth factor receptor T790M mutation-positive non-small cell lung cancer.
Detailed Description: - This is a multi-center, AZD9291 expanded access protocol for the treatment of adult patients with advanced/metastatic EGFR T790M mutation-positive non-small cell lung cancer (NSCLC) who have received prior EGFR TKI therapy and at least one additional line of therapy (≥ 3rd line). Local testing is accepted for confirmation of T790 mutation status. Eligible patients will be enrolled to receive AZD9291 (80mg orally, once daily) for as long as the access program remains open and they are continuing to show clinical benefit, as judged by the treating physician
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Anaheim, California, United States
Research Site, Beverly Hills, California, United States
Research Site, Burbank, California, United States
Research Site, Santa Barbara, California, United States
Research Site, Santa Rosa, California, United States
Research Site, Manchester, Connecticut, United States
Research Site, Boca Raton, Florida, United States
Research Site, Fleming Island, Florida, United States
Research Site, Athens, Georgia, United States
Research Site, Honolulu, Hawaii, United States
Research Site, Chicago, Illinois, United States
Research Site, Chevy Chase, Maryland, United States
Research Site, Boston, Massachusetts, United States
Research Site, Detroit, Michigan, United States
Research Site, Lansing, Michigan, United States
Research Site, Rochester, Minnesota, United States
Research Site, Lincoln, Nebraska, United States
Research Site, Paramus, New Jersey, United States
Research Site, Buffalo, New York, United States
Research Site, Fresh Meadows, New York, United States
Research Site, Mineola, New York, United States
Research Site, New York, New York, United States
Research Site, Charlotte, North Carolina, United States
Research Site, Winston Salem, North Carolina, United States
Research Site, Columbus, Ohio, United States
Research Site, Sioux Falls, South Dakota, United States
Research Site, Austin, Texas, United States
Research Site, Dallas, Texas, United States
Research Site, Fairfax, Virginia, United States
Research Site, Warrenton, Virginia, United States
Research Site, Lacey, Washington, United States
Research Site, Seattle, Washington, United States