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Brief Title: A Study of Giredestrant in Participants With Grade 1 Endometrial Cancer
Official Title: A Phase II, Single-Arm Study of Giredestrant in Patients With Grade 1 Endometrial Cancer
Study ID: NCT05634499
Brief Summary: This Phase II, global, single-arm study is designed to evaluate the efficacy, safety, and pharmacokinetics of giredestrant monotherapy in participants with Grade 1 endometrioid endometrial cancer.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Arizona Oncology - HOPE Wilmot, Tucson, Arizona, United States
University of Arkansas for Medical Sciences; Winthrop Rockefeller Cancer Institute, Little Rock, Arkansas, United States
Mount Sinai Medical Center, Miami Beach, Florida, United States
Minnesota Oncology Minneapolis, Minneapolis, Minnesota, United States
Nebraska Methodist Hospital, Omaha, Nebraska, United States
Englewood Health/Hematology Oncology Practice of Englewood (HOPE), Englewood, New Jersey, United States
Providence Portland Medical Center, Portland, Oregon, United States
Western Pennsylvania Hospital, Pittsburgh, Pennsylvania, United States
Texas Oncology Cancer Center, Austin, Texas, United States
Texas Oncology, P.A. - Fort Worth, Fort Worth, Texas, United States
Virginia Oncology Associates, Norfolk, Virginia, United States
Jewish General Hospital, Montreal, Quebec, Canada
McGill University Health Centre - Glen Site, Montreal, Quebec, Canada
Istituto Tumori Napoli;Unità Operativa Oncologia Medica Uro-Ginecologica, Napoli, Campania, Italy
Istituto Scientifico Romagnolo Per Lo Studio E La Cura Dei Tumori IRST - PPDS, Meldola, Emilia-Romagna, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Lazio, Italy
Narodowy Inst.Onkol.im.Sklodowskiej-Curie Panstw.Inst.Bad Gliwice; III Klin. Radioter. i Chemioter., Gliwice, , Poland
Swietokrzyskie Centrum Onkologii; Klinika Ginekologii, Kielce, , Poland
Narodowy Instytut Onkologii im. M.Sklodowskiej-Curie;Klinika Ginekologii Onkologicznej, Warszawa, , Poland
Name: Clinical Trials
Affiliation: Hoffmann-La Roche
Role: STUDY_DIRECTOR